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CHOLESTEROL: 作品数：637被引量：1503H指数：17; 导出分析报告; 相关作者：童华胡继明姚松年韩冰薛东芳更多>>; 相关机构：武汉大学中国医学科学院北京协和医学院中国科学院浙江大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划中国博士后科学基金国家教育部博士点基金更多>>

Dietary oxidized cholesterol causes mucus barrier thinner via decreasing Muc2 expression in the proximal colon and increasing the abundance of mucus-degrading bacteria: 《Food Science and Human Wellness》2025年第4期1251-1263,共13页Chi Yan Shouhe Huang Zixing Chen Huafang Ding Zhenyu Chen; supported by Hong Kong Research Grants Council General Research Fund(CUHK 14102321,14103722 and 14104923)。; Oxidized cholesterol(OXC)is a harmful dietary substance.Although the consumption of OXC has been associated with colonic inflammation,related underlying mechanisms are still limited.We evaluated the influence of dieta...; 关键词：Dietary oxidized cholesterol Gut microbiota Colonic inflammation Mucus barrier Western diets Inflammatory bowel diseases

Targeting cholesterol trafficking to mitigate axonal degeneration in hereditary spastic paraplegia: 《Neural Regeneration Research》2025年第5期1397-1398,共2页Zhenyu Chen Xue-Jun Li; supported by the NIH grant(RO1 NS118066);the Blazer Foundation(to XJL)。; Axonal degeneration underlies many debilitating diseases including hereditary spastic paraplegia(HSP),a genetically and clinically diverse group of disorders characterized by spasticity and weakness of the lower extre...; 关键词：DEGENERATION DISEASES HEREDITARY

Translocator protein and neurodegeneration: insights from Alzheimer’s disease: 《Neural Regeneration Research》2025年第4期1090-1091,共2页Arpit Kumar Pradhan Rainer Rupprecht Gerhard Rammes; supported by the German Research Foundation(Deutsche Forschungsgemeinschaft)(DFG),project number 422179811 to RR and RA 689/12-1 to GR.; The 18 kDa translocator protein(TSPO)located on the outer mitochondrial membrane regulates several key cellular processes including mitochondrial homeostasis,cholesterol transport,apoptosis,cell proliferation,and main...; 关键词：CHOLESTEROL ORGANS

Homozygous phytosterolemia and a literature review:A case report: 《World Journal of Clinical Cases》2025年第10期46-52,共7页Chun-Xin Jiang Guang Yang Lian-Ping Shi Peng-Yu Su; Supported by Natural Science Foundation of Heibei Province,No.H2020209160。; BACKGROUND Phytosterolemia,also known as sitosterolemia,is a rare autosomal recessive disease characterized by elevated plasma plant sterol levels and xanthomata,which is easily misdiagnosed as familial hypercholester...; 关键词：HYPERCHOLESTEROLEMIA CHOLESTEROL Low-density lipoprotein Phytosterolemia Liquid chromatography ABCG5/ABCG8 Sitosterolemia

Finding the balance: Modifying the cholesterol and steroidal glycoalkaloid synthesis pathway in tomato(Solanum lycopersicum L.) for human health, fruit flavor, and plant defense: 《Horticultural Plant Journal》2025年第1期42-56,共15页Vincenzo Averello IV Adrian D.Hegeman Changbin Chen; Unlike most plants, members of the genus Solanum produce cholesterol and use this as a precursor for steroidal glycoalkaloids. The production of the compounds begins as a branch from brassinosteroid biosynthesis, whic...; 关键词：CHOLESTEROL Steroidal glycoalkaloids TOMATO Biosynthesis a-tomatine STEROLS TERPENOIDS Plant defense

The Mediterranean Diet A lifestyle plan that offers delicious food and health benefits galore: 《空中英语教室(高级版.彭蒙惠英语)》2025年第1期14-15,42,43,共4页Gretchen McKay; Healthful eating is important at any age to lower the risk of obesity and keep the heart and the body functioning well.This becomes especially crucial later in life because good nutrition helps reduce the risk of chro...; 关键词：CHOLESTEROL CARDIOVASCULAR OBESITY

Optimized lipid nanoparticles enable effective CRISPR/Cas9-mediated gene editing in dendritic cells for enhanced immunotherapy: 《Acta Pharmaceutica Sinica B》2025年第1期642-656,共15页Kuirong Mao Huizhu Tan Xiuxiu Cong Ji Liu Yanbao Xin Jialiang Wang Meng Guan Jiaxuan Li Ge Zhu Xiandi Meng Guojiao Lin Haorui Wang Jing Han Ming Wang Yong-Guang Yang Tianmeng Sun; supported by grants from National Key Research and Development Program of China(2021YFA1100700);National Natural Science Foundation of China(82325029,32171379,U22A20156,China);Department of Human Resource and Social Security of Jilin Province(2022DJ02,China);the Bethune Medical Department of Jilin University(2022JBGS01,China);the Fundamental Research Funds for the Central Universities,Jilin University(China).; Immunotherapy has emerged as a revolutionary approach to treat immune-related diseases.Dendritic cells(DCs)play a pivotal role in orchestrating immune responses,making them an attractive target for immunotherapeutic i...; 关键词：Lipid nanoparticles Cholesterol density CRISPR/Cas9 Gene editing Dendritic cells PD-L1 IMMUNOTHERAPY Immune-related diseases

Correlation of Helicobacter pylori infection with high-density lipoprotein cholesterol levels and pulse wave conduction velocity: 《Clinical Research Communications》2024年第4期33-38,共6页Yue-Xi Li Xiao-Qin Liu Yu-Han Luo Qiao-Li Wang; The Sichuan Medical and Health Care Promotion Institute Research Project(KY2022SJ0100).; Background:Helicobacter pylori(HP)is associated with several gastrointestinal diseases,including peptic ulcer diseases and gastric cancer,and non-gastrointestinal diseases such as hypertension and Alzheimer's disease....; 关键词：Helicobacter pylori CHOLESTEROL high-density lipoprotein ATHEROSCLEROSIS

Helicobacter pylori infection is associated with the risk and phenotypes of cholelithiasis:A multi-center study and meta-analysis被引量：1: 《World Journal of Gastroenterology》2024年第47期4991-5006,共16页Shuo-Yi Yao Xin-Meng Li Ting Cai Ying Li Lun-Xi Liang Xiao-Ming Liu Yu-Feng Lei Yong Zhu Fen Wang; Supported by the National Natural Science Foundation of China,No.82270594;the National Natural Science Foundation for Youths of China,No.82103151;the Outstanding Youth Foundation of Hunan Province,No.2022JJ20092;the Wisdom Accumulation and Talent Cultivation Project of Third Xiangya Hospital of Central South University,No.YX202103.; BACKGROUND Helicobacter pylori(H.pylori)is a prevalent pathogen associated with various diseases.Cholelithiasis is also a common condition.H.pylori infection has been identified in the biliary system,suggesting its po...; 关键词：Helicobacter pylori CHOLELITHIASIS BILIRUBIN CHOLESTEROL MULTI-CENTER

Early intermittent cholesterol exposure accelerates atherosclerosis:an oscillating amplifier calling for preemptive control: 《Signal Transduction and Targeted Therapy》2024年第12期5343-5345,共3页Maria Kral Yvonne Döring Christian Weber; support was received for the research,authorship,and/or publication of this article;supported in part by funding to YD and CW through the Deutsche Forschungsgemeinschaft(SFB1123-A1).; A recent publication in Nature1 identified early intermittent hyperlipidemia as a new determinant of atherosclerosis driving an altered phenotype of arterial-resident macrophages with defects in autophagy-and efferocy...; 关键词：AMPLIFIER YOUNGER driving

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