HYPERCHOLESTEROLEMIA

作品数：101被引量：227H指数：8
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相关领域：医药卫生更多>>
相关作者：秦玉刘云付卿卿陈欣杰徐向华更多>>
相关机构：中国福利会国际和平妇幼保健院第三军医大学首都医科大学中国南方航空股份有限公司更多>>
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Homozygous phytosterolemia and a literature review:A case report
《World Journal of Clinical Cases》2025年第10期46-52,共7页Chun-Xin Jiang Guang Yang Lian-Ping Shi Peng-Yu Su 
Supported by Natural Science Foundation of Heibei Province,No.H2020209160。
BACKGROUND Phytosterolemia,also known as sitosterolemia,is a rare autosomal recessive disease characterized by elevated plasma plant sterol levels and xanthomata,which is easily misdiagnosed as familial hypercholester...
关键词：HYPERCHOLESTEROLEMIA CHOLESTEROL Low-density lipoprotein Phytosterolemia Liquid chromatography ABCG5/ABCG8 Sitosterolemia 
Punicalagin alleviates hypercholesterolemia in mice through modulating farnesoid X receptor signaling and modulating gut microbiota
《Food Science and Human Wellness》2025年第1期175-189,共15页Huanhuan Liu Hongli Liu Chunhong Yan Jiaxiu Liu Yu Cao Guopeng Li Xiaodong Xia 
supported in part by the National Key Research and Development Program of China(2022YFD2100104);the Science and Technology Program of Shaanxi Province,China(2022JM-111);Graduate Innovation Fund of Dalian Polytechnic University。
Punicalagin has been demonstrated to exhibit anti-oxidant and anti-inflammatory properties,but whether and how it could impact hypercholesterolemia remains not fully explored.The aim of this study was to investigate t...
关键词：PUNICALAGIN HYPERCHOLESTEROLEMIA Farnesoid X receptor Bile acid metabolism Gut microbiota 
Prevalence of cardiometabolic co-morbidities in patients with vs persons without chronic hepatitis B: The FitLiver cohort study
《World Journal of Hepatology》2025年第1期73-85,共13页Sofie Jespersen Asmita Fritt-Rasmussen Sten Madsbad Bente K Pedersen Rikke Krogh-Madsen Nina Weis 
Supported by The Centre for Physical Activity Research(CFAS),TrygFonden,No.125132;and The Beckett Foundation,No.22-2-9924.
BACKGROUND Chronic hepatitis B(CHB)affects>300 million people worldwide.The combi-nation of CHB and cardiometabolic co-morbidities increases the risk of liver-related morbidity and mortality.However,international guid...
关键词：Viral hepatitis B Diabetes Metabolic dysfunction-associated steatotic liver disease Hypertension HYPERCHOLESTEROLEMIA Obesity Physical activity 
Food-derived peptides with inhibitory capacity for HMG-CoA reductase activity: a potential nutraceutical for hypercholesterolemia
《Food Science and Human Wellness》2024年第6期3083-3094,共12页Guillermo Santos-Sánchez Ana IsabelÁlvarez-López Eduardo Ponce-España Patricia Judith Lardone Antonio Carrillo-Vico Ivan Cruz-Chamorro 
funded by Consejería de Salud, Junta de Andalucía (PC-0111-2016-0111);PEMP-0085-2020 (cofinanciado con fondos FEDER, convocatoria Resolución de 7 de julio de 2021 de la Secretaría General de Investigación, Desarrollo e Innovación en Salud, que convoca subvenciones para financiar la investigación, el desarrollo y la innovación en Biomedicina y Ciencias de la Salud en Andalucía, para 2021);the Programa PAIDI from the Junta de Andalucía (CTS160);supported by a FPU grant from the Spanish Ministerio de Educación, Cultura y Deporte (FPU16/02339);supported by the VI Program of Inner Initiative for Research and Transfer of the University of Seville (VIPPIT2020-II.4);by a postdoctoral fellowship from the Andalusian Government Ministry of Economy, Knowledge, Business, and University (DOC_00587/2020);funded by Andalusian Government Ministry of Health (PI-0136-2019);supported by the VI Program of Inner Initiative for Research and Transfer of University of Seville
Cardiovascular diseases(CVDs)are the leading global cause of mortality and disease burden.Statins are the most prescribed lipid-lowering drugs to treat hypercholesterolemia and prevent CVDs.The biochemical mechanism o...
关键词：Functional foods Cholesterol Cardiovascular diseases STATINS 3-Hydroxy-3-methylglutaryl-coenzyme A 
Aclysiran,an RNAi therapeutic agent targeting ACLY,treats hypercholesterolemia and atherosclerosis in ApoE^(-/-)mice
《Acta Pharmaceutica Sinica B》2024年第12期5505-5508,共4页Meijie Chen Peter J.Little Sudong Kong Maciej Banach Jianping Weng Suowen Xu 
supported by grants from the National Key R&D Program of China(Grant No.2021YFC2500500);the National Natural Science Foundation of China(Grant Nos.82370444,82070464,12411530127);supported by the Program for Innovative Research Team of The First Affiliated Hospital of USTC(CXGG02,China);Anhui Provincial Natural Science Foundation(Grant No.2208085J08,China).
To the editor:ATP-citrate lyase(ACLY)is the key enzyme linking glucose catabolism to lipogenesis.Targeting hepatic ACLY for lowering low density lipoprotein-cholesterol(LDL-C)and attenuating atherosclerosis has been v...
关键词：Aclysiran ACLY ATHEROSCLEROSIS 
Overview of dyslipidemia and metabolic syndrome in myeloproliferative neoplasms
《World Journal of Clinical Oncology》2024年第6期717-729,共13页Mihnea-Alexandru Găman Bahadar Singh Srichawla Yong-Feng Chen Poulami Roy Arkadeep Dhali Ahmed Nahian Muhammad Romail Manan Vincent Kipkorir Richard Christian Suteja Lakshmi Venkata Simhachalam Kutikuppala Amelia Maria Găman Camelia Cristina Diaconu 
Supported by the Grant Funded by Competitiveness Operational Programme A1.1.4.ID:P_37_798 MYELOAL-EDIAPROT(to Găman MA),No.149/26.10.2016(MySMIS2014+:106774).
Myeloproliferative neoplasms(MPNs)occur due to the abnormal proliferation of one or more terminal myeloid cell lines in peripheral blood.Subjects suffering from MPNs display a high burden of cardiovascular risk factor...
关键词：Polycythemia vera Essential thrombocythemia MYELOFIBROSIS Cardiovascular disease HYPERCHOLESTEROLEMIA HYPERTRIGLYCERIDEMIA OBESITY Diabetes Inflammation Oxidative stress 
Ferroptosis mediators vary in metabolic syndrome,type-2 diabetes,and hypercholesterolemia:A meta-analysis report
《Genes & Diseases》2024年第3期109-112,共4页Indra Kundu Ashlesha Pande Tannishtha Das Susan Idicula-Thomas 
This work(RA/1346/11-2022)was supported by grants received from the Department of Biotechnology,Ministry of Science and Technology;Government of India(BT/PR40165/BTIS/137/12/2021);Science and Engineering Research Board(India)(STR/2020/000034);the Indian Council of Medical Research,India(BMI/11(51)/2022).
Metabolic syndrome(MetS)is a complex disorder characterized by the coexistence of phenotypes such as obesity,hypertension,hyperglycemia,high triglyceride level,and low level of high-density lipoprotein cholesterol.Inf...
关键词：OBESITY CHOLESTEROL DIABETES 
The current trend and challenges of developing red yeast rice-based food supplements for hypercholesterolemia被引量：1
《Journal of Future Foods》2023年第4期312-329,共18页Gong Chen Wanbo Chen Jinhong Xu Guodong Ma Xinge Hu Guoxun Chen 
the Diabetes Action Research and Education Foundation for the research grant(#466)to G.Chen.
Hypercholesterolemia is a risk factor of cardiovascular diseases,which have been managed using statin drugs.Red yeast rice(RYR)as a traditional food in the Eastern Asia countries has anti-hyperlipidemia activity.Recen...
关键词：Cardiovascular diseases CHOLESTEROL Human clinical trials Food supplement HYPERCHOLESTEROLEMIA Monacolins Red yeast rice 
Prognostic implication of early posttransplant hypercholesterolemia in liver transplantation for patients with hepatocellular carcinoma
《Hepatobiliary & Pancreatic Diseases International》2023年第3期228-238,共11页Rong-Li Wei Guang-Han Fan Chen-Zhi Zhang Kang-Chen Chen Wen-Hui Zhang Chang-Biao Li Si-Yi Dong Jun-Li Chen Sun-Bin Ling Shu-Sen Zheng Xiao Xu 
supported by grants from the National Natural Science Funds for Distinguished Young Scholars of China (81625003);the Key Program,National Natural Science Foundation of China (81930016);the Key Research&Development Plan of Zhejiang Province (2019C03050)。
Background: Hyperlipidemia is a common complication after liver transplantation(LT) and develops mostly in the early posttransplant period. Recently, some studies have reported a positive correlation between hyperlipi...
关键词：Liver transplantation Hepatocellular carcinoma HYPERCHOLESTEROLEMIA PROGNOSIS 
Compound Danshen Dripping Pill inhibits hypercholesterolemia/atherosclerosis-induced heart failure in ApoE and LDLR dual deficient mice via multiple mechanisms被引量：5
《Acta Pharmaceutica Sinica B》2023年第3期1036-1052,共17页Yanfang Yang Ke Feng Liying Yuan Yuxin Liu Mengying Zhang Kaimin Guo Zequn Yin Wenjia Wang Shuiping Zhou He Sun Kaijing Yan Xijun Yan Xuerui Wang Yajun Duan Yunhui Hu Jihong Han 
supported by the China NSFC grants 82173807 to Yajun Duan and 81973316 to Jihong Han;Tianjin Municipal Science and Technology Commission of China Grant 20JCZDJC00710;the Fundamental Research Funds for the Central Universities(Nankai University,China)63211045 to Jihong Han.
Heart failure is the leading cause of death worldwide.Compound Danshen Dripping Pill(CDDP)or CDDP combined with simvastatin has been widely used to treat patients with myocardial infarction and other cardiovascular di...
关键词：Compound danshen dripping pill Heart failure HYPERCHOLESTEROLEMIA Atherosclerosis Simvastatin ApoE^(-/-)LDLR^(-/-)mice Inflammation Oxidative stress 
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