OBESITY

作品数：1895被引量：5513H指数：28
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相关作者：郭锡熔李雪飞刘倩琦张思仲刘合焜更多>>
相关机构：北京大学四川大学华西医院中山大学华中科技大学更多>>
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相关基金：国家自然科学基金国家重点基础研究发展计划中国博士后科学基金湖北省自然科学基金更多>>
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Fat mass and obesity-mediated N^(6)-methyladenosine modification modulates neuroinflammatory responses after traumatic brain injury
《Neural Regeneration Research》2026年第2期730-741,共12页Xiangrong Chen Jinqing Lai Zhe Wu Jianlong Chen Baoya Yang Chunnuan Chen Chenyu Ding 
supported by grants from the Major Projects of Health Science Research Foundation for Middle-Aged and Young Scientist of Fujian Province,China,No.2022ZQNZD01010010;the National Natural Science Foundation of China,No.82371390;Fujian Province Scientific Foundation,No.2023J01725(all to XC).
The neuroinflammatory response mediated by microglial activation plays an important role in the secondary nerve injury of traumatic brain injury.The post-transcriptional modification of N^(6)-methyladenosine is ubiqui...
关键词：ADAM17 epigenetic modification fat mass and obesity N6-methyladenosine MICROGLIA mRNA nerve injury NEUROINFLAMMATION traumatic brain injury tumor necrosis factorα 
Microbial fermentation of blue honeysuckle(Lonicera caerulea L.)polyphenol promotes insulin secretion and intervenes in obesity by promoting short-chain fatty acids production
《Food Science and Human Wellness》2025年第4期1449-1468,共20页Fangyi Pei Xinbo Cao Yanxin Ren Liangyang Mao Yueyi Liu Jingping Ge Wenxiang Ping 
supported by the Key Program of Heilongjiang Provincial Natural Science Foundation of China(ZD2020C008);the National Natural Science Foundation of China(32071519);the Heilongjiang University Graduate Innovation Research Project(YJSCX2022-031HLJU);the Qiqihar Science and Technology Plan Joint Guidance Project(LSFGG-2022037);Scientific Research Project of Ecological Environment Protection of Heilongjiang Provincial Department of Ecological Environment(HST2022TR004)。
During obesity treatment,clinicians have been burdened by the ever-increasing number of patients and the side effects of drug treatment.Finding new plant-derived active ingredients as an intervention for obesity has b...
关键词：OBESITY Blue honeysuckle POLYPHENOL Short-chain fatty acids In vitro fecal fermentation 
Elucidating the anti-obesity phytochemicals in Chenpi and their molecular mechanisms
《Food Science and Human Wellness》2025年第4期1224-1238,共15页Jinhai Luo Weiqi Yan Zhi Chen Baojun Xu 
supported by the Guangdong Provincial Key Laboratory IRADS(2022B1212010006,R0400001-22)。
Obesity has become a significant global public health issue.Previous studies have found that the Chenpi has the anti-obesity activity.However,the anti-obesity phytochemicals and their mechanisms are still unclear.This...
关键词：Chenpi PHYTOCHEMICALS OBESITY Network pharmacology Molecular mechanism Signaling pathway 
Lard reduces obesity in mice compared with corn oil and canola oil via modulating gut microbiota and bile acid metabolism
《Food Science and Human Wellness》2025年第3期1080-1091,共12页Wusun Li Weida Wu Yuhui Zhang Xiaoyan Tang Xin Zheng Xinyuan Huang 
funded by Basic Research Fund of Chinese Academy of Agricultural Sciences(CAAS)(1610072021001);the China Agriculture Research System(CARS-35);the Agricultural Science and Technology Innovation Program of CAAS。
The association between dietary fat types and obesity is controversial,and the underlying mechanism remains unclear.This study aimed to evaluate the effect of different dietary fat sources(lard,corn oil or canola oil)...
关键词：Dietary fats OBESITY LARD Gut microbiota Bile acid Farnesoid X receptor 
Obesogenic effects of six classes of emerging contaminants
《Journal of Environmental Sciences》2025年第5期252-272,共21页Siying Wu Chaoyu Tong Jing Liu 
supported by the National Key Research&Development Programof China,Ministry of Science and Technology(Nos.2022YFE0134900 and 2022YFC3703200);the Key Research and Development Programof Zhejiang Province,China(No.2024C03228);the National Nature Science Foundation of China(Nos.22376184 and 22076166).
There is growing concern about the concept that exposure to environmental chemicals may be contributing to the obesity epidemic.However,there is no consensus on the obesogenic effects of emerging contaminants from a t...
关键词：Emerging contaminants OBESITY Human exposure PRESERVATIVES Flame retardants Plasticizers ANTIBIOTICS 
Effect of beinaglutide,a thrice-daily GLP-1 receptor agonist,on body weight and metabolic parameters:A systematic review and metaanalysis
《World Journal of Diabetes》2025年第5期374-387,共14页Abul Bashar Mohammad Kamrul-Hasan Vanishri Ganakumar Lakshmi Nagendra Deep Dutta M Rafiqul Islam Joseph M Pappachan 
BACKGROUND Beinaglutide,a short-acting glucagon-like polypeptide-1 receptor agonist,has shown variable efficacy in weight reduction and metabolic control in randomized controlled trials(RCTs).AIM To summarize the ther...
关键词：Beinaglutide Glucagon-like polypeptide-1 receptor agonist OBESITY Type 2 diabetes Weight reduction Metaanalysis 
Investigating the controversial link between pediatric obesity and graft survival in kidney transplantation
《World Journal of Nephrology》2025年第2期53-64,共12页Brooke Stanicki Dante A Puntiel Benjamin Peticca Nicolas Egan Tomas M Prudencio Samuel G Robinson Sunil S Karhadkar 
BACKGROUND Childhood obesity is a significant public health concern,particularly amongst children with chronic kidney disease requiring kidney transplant(KT).Obesity,defined as a body mass index(BMI)of 30 kg/m²or grea...
关键词：KIDNEY TRANSPLANTATION Graft failure PEDIATRIC OBESITY UNDERWEIGHT 
Helicobacter pylori infection is linked to metabolic dysfunction and associated steatotic liver disease:A large cross-sectional study
《World Journal of Gastroenterology》2025年第13期79-88,共10页Lin Ye Kai Yan Ze Tian Zhi-Hua Xiao Ru-Yi Xie Zheng-Yuan Xie Li Tao 
Supported by Science and Technology Research Program of Jiangxi Provincial Department of Education,No.GJJ210225;2022 Provincial Health and Wellness Committee Science and Technology Program Projects,No.20221096;Jiangxi Provincial Natural Science Foundation's Young Scientists Fund,No.20242BAB20358.
BACKGROUND Helicobacter pylori(H.pylori),a globally widespread pathogen affecting half of the global population,has been increasingly implicated in metabolic disorders,including obesity,dyslipidemia,and metabolic dysf...
关键词：Helicobacter pylori OBESITY Blood glucose Lipid profile Blood pressure Metabolic dysfunction-associated steatotic liver disease 
Curcumol ameliorates diabetic retinopathy via modulating fat mass and obesity-associated protein-demethylated MAF transcription factor G antisense RNA 1
《World Journal of Diabetes》2025年第4期220-235,共16页Han Rong Yu Hu Wei Wei 
BACKGROUND Diabetic retinopathy(DR)is a major microvascular complication of diabetes mellitus,leading to significant visual impairment and blindness among adults.Current treatment options are limited,making it essenti...
关键词：Diabetic retinopathy CURCUMOL MAF transcription factor G antisense RNA 1 Fat mass and obesity-associated protein Diabetes mellitus 
BBOX1,LACC1,MMP7 and SSTR1 as common predictors in obesity and non-alcoholic fatty liver disease
《Genes & Diseases》2025年第2期57-59,共3页Chaoyuan Huang Guoming Chen Dongqiang Luo Jiyuan Zheng Nan Zhong Danyun Li Yang Luo Peizhen Huang Ning Wang Yibin Feng Yiyuan Zheng 
funded by the National Natural Science Foundation of China (No.82104549);the China Postdoctoral Science Foundation (No.2022M722158);Shanghai Medical Innovation&Development Foundation (No.WL-YXBS-2022001K).
Obesity is one of the major risk factors of non-alcoholic fatty liver disease(NAFLD),however,the reliable diagnostic markers are not fully known.The purpose of this study is to clarify the shared pathophysiological di...
关键词：co-first authors: 
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