supported by the Science and Technology Council,Taiwan,China(NSTC 112-2320-B-039-057 and MOST 111-2320-B-039-067-MY3);the China Medical University,Taiwan,China(CMU112-S-18),awarded to Yuan-Soon Ho;the China Medical University,Taiwan,China(CMU112-N-02),awarded to Li-Ching Chen;the Science and Technology Council,Taiwan,China(MOST 110-2320B-039-079)。
This study presents novel findings on the potential of phloretin,an apple polyphenol,to enhance the effectiveness of anti-human epidermal growth factor receptor-2(HER2)antibody therapy in HER2-positive breast cancer p...
supported by the Key Program of Heilongjiang Provincial Natural Science Foundation of China(ZD2020C008);the National Natural Science Foundation of China(32071519);the Heilongjiang University Graduate Innovation Research Project(YJSCX2022-031HLJU);the Qiqihar Science and Technology Plan Joint Guidance Project(LSFGG-2022037);Scientific Research Project of Ecological Environment Protection of Heilongjiang Provincial Department of Ecological Environment(HST2022TR004)。
During obesity treatment,clinicians have been burdened by the ever-increasing number of patients and the side effects of drug treatment.Finding new plant-derived active ingredients as an intervention for obesity has b...
financially supported by the National Natural Science Foundation of China(No.52373271).
Electromagnetic synergy and porous characteristics are two dominant factors in realizing light-weight and high-efficient microwave absorption performance.In this paper,a formaldehydeassisted metal-ligand crosslinking ...
supported by 2024 Liaoning Province Graduate Education Teaching Reform Research Project(LNYJG2024251).
The aim of this study was to explore the mechanism of action of sea buckthorn polyphenols in the treatment of hyperlipidemia through network pharmacology and molecular docking.The TCMSP pharmacology database was used ...
Quinoa is pseudo cereal and considered as full nutritional food for its functional ingredients such as peptides,polysaccharides,saponins and polyphenols.Up to now,over 20 phenolic compounds have been reported in quino...
supported by NIH grants, NINDS R21 NS116720 and NINDS/NIA RF1 NS130681 (to RG and WJM)。
The dietary polyphenolic compounds resveratrol and quercetin prevent neurodegenerative diseases in experimental models;however, they reach the brain only in nanomolar concentrations in the glucuronidated and sulfated ...
supported by the National Natural Science Foundation of China(No.32201077);Guangdong Basic and Applied Basic Research Foundation(No.2022A1515011982);Foundation of the Department of Education of Guangdong Province(No.2022KTSCX144),Basic Research Program of Guangzhou Science and Technology Bu;reau(G24151031);Guangdong Province University Characteristic Innovation Project(06-410-1013);Chinese Post-doctoral Science Foundation(2023M740847);the Project of the State Key Laboratory of Respiratory Disease(SKLRD-Z-202105);Science and Technology Innovation Project of Foshan City(1920001000025).
Current treatments for diabetic wounds have some curative effect,but the process is complicated and lack user-friendly wound dressings.Nanozymes have gained significant attention for wound healing due to their strik-i...
supported by the National Natural Science Foundation of China(U23A20526,32072220,32270420);Shanxi Province 136 Revitalization Medical Project Construction Funds(general surgery department),Science Foundation(202103021224011).
Inflammatory bowel disease(IBD)is a chronic relapsing-remitting systemic disease of the gastrointestinal tract,characterized by an inflammatory process.Gut mycobiota community dysbiosis has been reported that is close...
Fundamental Research Funds for Central Universities(202241010);Natural Science Fund for Excellent Young Scholars of Shandong Province(ZR202110120029);Major science and technology projects(110202201020(LS-04));Open Project of the Key Laboratory for Tobacco Disease and Pest Monitoring and Comprehensive Management in the Tobacco Industry(KLTPMIMT2022-11).
Chronic bioenergetic imbalances and inflammation caused by hyperglycemia are obstacles that delay diabetic wound healing.However,it is difficult to directly deliver energy and metabolites to regulate intracellular ene...
supported by the National Natural Science Foundation of China(Nos.22305042(Tiancong Zhao),22075049(Xiaomin Li),21875043(Xiaomin Li),82201748(Xiaomin Li));the Fundamental Research Funds for the Central Universities(No.20720220010(Xiaomin Li));the Natural Science Foundation of Shanghai(No.22ZR1478900(Xiaomin Li));the Shanghai Rising-Star Program(Nos.20QA1401200(Xiaomin Li),22YF1402200(Tiancong Zhao),21YF1459200(Xiaomin Li));Shanghai Pilot Program for Basic Research-Fudan University(No.22TQ004);Young Elite Scientist Sponsorship Program by Chinese Chemical Society(Tiancong Zhao),Xiaomi Young Talents Program(Tiancong Zhao),Qatar Research Development and Innovation Council(No.ARG01-0602-230467).
The excessive reactive oxygen species (ROS) accumulation and overactivated osteoclastogenesis in subchondral bone has proved to be a major cause of osteoarthritis (OA). Scavenging of ROS microenvironment to inhibit th...