RESVERATROL

作品数：310被引量：1443H指数：18
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Resveratrol inhibit the proliferation and migration of HepG2 cells through SIRT1-MAPK signaling pathway
《Food and Health》2025年第1期22-28,共7页Chen-Chen Feng Yi-Jiao Xu Yu Chen Wan-Wei Yang Xiao Wei Ren-Dong Zheng 
supported by Natural Science Foundation of Nanjing University of Chinese Medicine(XZR2023010);Traditional Chinese Medicine Science and Technology Project of Jiangsu Province(QN202212);Guidance Program of Jiangsu Commission of Health(Z2020046).
Background: Resveratrol is a widely recognized anti-inflammatory and antioxidant agent,and it has been suggested to possess anti-tumor effects. But the effect of resveratrol onhepatocellular carcinoma and its molecula...
关键词：RESVERATROL Hepatocellular carcinoma HepG2 cells SIRT1 MAPK 
Computational interrogation of natural compounds identified resveratrol-3-O-D-glucopyranoside as a potential inhibitor of essential monkeypox virus proteins
《Intelligent Medicine》2025年第1期5-13,共9页Oluwafemi A.Adepoju Ammar Usman Danazumi Lamin BS Dibba Bashiru Ibrahim Salahuddin Iliyasu Gital Joseph Gideon Ibrahim Maliyogbinda L.Jibrailu Emmanuel O.Balogun 
supported by the Fogarty International Center of the National Institutes of Health(Grant No.K43TW012015).
Background Monkeypox has become a significant public health concern owing to the recent epidemics and associated morbidity.The treatment is limited by the availability of drugs,especially in endemic communities.Comput...
关键词：Monkeypox virus Drug discovery Computational methods DOCKING Molecular dynamics simulation SuperNatural compounds 
Resveratrol and pancreatic cancers:Questions and future perspectives
《World Journal of Gastrointestinal Oncology》2025年第3期9-12,共4页Olga A Sukocheva 
There is still no effective treatment for pancreatic cancer,one of the deadliest malignancies among the gastrointestinal diseases.Jiang et al demonstrated the presence of senescent cancer-associated fibroblasts(CAFs)i...
关键词：Pancreatic cancer RESVERATROL Cancer-associated fibroblasts Tumor microenvironment ANTIOXIDANT Immune senescence 
Neuroprotection by resveratrol-glucuronide and quercetin-glucuronide via binding to polyphenol-and glycosaminoglycan-binding sites in the laminin receptor
《Neural Regeneration Research》2025年第3期819-820,共2页Rayudu Gopalakrishna Jennifer Aguilar Emily Lee William J.Mack 
supported by NIH grants, NINDS R21 NS116720 and NINDS/NIA RF1 NS130681 (to RG and WJM)。
The dietary polyphenolic compounds resveratrol and quercetin prevent neurodegenerative diseases in experimental models;however, they reach the brain only in nanomolar concentrations in the glucuronidated and sulfated ...
关键词：RESVERATROL MOLAR dated 
Integration of Melanin-Resveratrol Nanosystem for the Diagnostic-therapeutic of Renal Fibrosis
《Chemical Research in Chinese Universities》2025年第1期86-94,共9页LI Tingting JIAMengni JI Huifang ZHANG Ruiping 
supported by the Project of the Key Laboratory of Nano-imaging and Drug-loaded Preparation of Shanxi Province,China(No.202104010910010);the Project funded by China Postdoctoral Science Foundation(No.2022M722001);the Natural Science Foundation for Shanxi Province,China(No.202103021224241);the Special Fund from Medicinal Basic Research Innovation Center of Chronic Kidney Disease,Ministry of Education,Shanxi Medical University,China(No.CKD/SXMU-2024-11).
In this work,melanin nanoparticle-resveratrol(MNP-RES)nanosystem was excogitated and constructed for the treatment and imaging of folate-induced renal fibrosis(RF)mice model to fulfill the combination of diagnosis and...
关键词：MELANIN RESVERATROL Diagnostic-therapeutic nanosystem Dual-modal imaging Renal fibrosis 
Resveratrol promotes mitophagy via the MALAT1/miR-143-3p/RRM2 axis and suppresses cancer progression in hepatocellular carcinoma
《Journal of Integrative Medicine》2025年第1期79-92,共14页Chun-yan Feng Cheng-song Cai Xiao-qian Shi Zhi-juan Zhang Dan Su Yun-qing Qiu 
supported by the Zhejiang Provincial Science and Technology Department Key Research and Development Plan(No.2020C03046).
Objective Resveratrol(Res)is a promising anticancer drug against hepatocellular carcinoma(HCC),but whether its anti-HCC effects implicate mitophagy remains unclear.Therefore,we aimed to explore the specific role of Re...
关键词：Hepatocellular carcinoma RESVERATROL MITOPHAGY MALAT1 miR-143-3p 
A quinolinyl analog of resveratrol improves neuronal damage after ischemic stroke by promoting Parkin-mediated mitophagy
《Chinese Journal of Natural Medicines》2025年第2期214-224,共11页Qingqi Meng Yan Mi Libin Xu Yeshu Liu Dong Liang Yongping Wang Yan Wang Yueyang Liu Guoliang Chen Yue Hou 
supported by the National Natural ScienceFoundation of China (No.82174076);the Construction Project of Liaoning Provincial Key Laboratory,China (No.2022JH13/10200026);the Fundamental Research Funds for the Central Universities (No.N2220002);the 111 Project (No.B16009);the Research Project of Educational Commission of Liaoning Province (No.LJ212410164003)。
Ischemic stroke(IS)is a prevalent neurological disorder often resulting in significant disability or mortality.Resveratrol,extracted from Polygonum cuspidatum Sieb.et Zucc.(commonly known as Japanese knotweed),has bee...
关键词：(E)-4-(3 5-dimethoxystyryl)quinoline RESVERATROL Ischemic stroke MITOPHAGY PARKIN 
Enhanced BBB penetration and microglia-targeting nanomodulator for the two-pronged modulation of chronically activated microglia-mediated neuroinflammation in Alzheimer's disease
《Acta Pharmaceutica Sinica B》2025年第2期1098-1111,共14页Ya Wei Xue Xia Xiaorong Wang Wenqin Yang Siqin He Lulu Wang Yongke Chen Yang Zhou Feng Chen Hanmei Li Fu Peng Guobo Li Zheng Xu Jintao Fu Huile Gao 
supported by the National Natural Science Foundation of China(82373801,China);Key Science and Technology Project of Hainan Province(ZDYF2024SHFZ058);the Fundamental of Research Funds for the Central Universities.
Intervention in chronically activated microglia-mediated neuroinflammation is a novel approach to treat Alzheimer's disease(AD).The low permeability of the blood-brain barrier(BBB)and non-selective distribution in the...
关键词：Blood-brain barrier penetration Microglial targeting Microglial modulation Chronic neuroinflammation Alzheimer’s disease IMMUNOTHERAPY TREM2 Resveratrol Alzheimer’s disease IMMUNOTHERAPY TREM2 RESVERATROL 
Dietary (poly)phenol intake is associated with cardiometabolic health parameters in adolescents
《Food Science and Human Wellness》2024年第6期3381-3390,共10页Emily P.Laveriano-Santos Sara Castro-Barquero Camila Arancibia-Riveros Ana María Ruiz-León Rosa Casas Ramón Estruch Patricia Bodega Mercedes de Miguel Amaya de Cos-Gandoy Jesús Martínez-Gómez Gloria Santos-Beneit Juan M.Fernández-Alvira Rodrigo Fernández-Jiménez Rosa M.Lamuela-Raventós Anna Tresserra-Rimbau 
supported by the SHE Foundation,“la Caixa”Foundation(LCF/PR/CE16/10700001);the Fundacióla Maratóde TV3(grant number 369/C/2016)and by the funding from Idilia Foods(FBG 311240);Support was also provided by the Ministerio de Ciencia,Innovación y Universidades(PID2020-114022RB-I00);CIBEROBN from the Instituto de Salud Carlos III,ISCIII from the Ministerio de Ciencia,Innovación y Universidades,(AEI/FEDER,UE);Generalitat de Catalunya.J.Martínez-Gómez is a postgraduate fellow of the Ministerio de Ciencia e Innovación of Spain at the Residencia de Estudiantes(2020–ongoing);R.F-J is a recipient of grant PI19/01704 funded by the Fondo de Investigación Sanitaria-Instituto de Salud Carlos III(ISCIII);co-funded by the European Regional Development Fund/European Social Fund“A way to make Europe”/“Investing in your future”.The CNIC is supported by the ISCIII,the Ministerio de Ciencia e Innovación(MCIN)and the Pro CNIC Foundation,and is a Severo Ochoa Center of Excellence(CEX2020-001041-S funded by MICIN/AEI/10.13039/501100011033);G.Santos-Beneit is the recipient of grant LCF/PR/MS19/12220001 funded by“la Caixa”Foundation(ID 100010434);A.Tresserra-Rimbau is a Serra Húnter Fellow.E.P.Laveriano-Santos is a FI-SDUR(EMC/503/2021)fellow from the Generalitat de Catalunya.
The protective role of(poly)phenols against metabolic disorders has been extensively studied in adults but not in adolescents.To assess associations of dietary(poly)phenols and their subclasses with cardiometabolic he...
关键词：PHYTOCHEMICAL RESVERATROL Lignan Flavan-3-ols ANTHOCYANIN Cardiovascular health TEENAGERS 
Synergistic effects of resveratrol with gemcitabine in pancreatic cancer chemotherapy by inhibiting the c-Met/PARP1 axis
《Journal of Pancreatology》2024年第4期267-278,共12页Shuai Wu Jiaqiang Ren Weikun Qian Mengyuan Gong Jie Li Tao Qin Simei Zhang Wunai Zhang Hao Sun Zheng Wu Zheng Wang Qingyong Ma Wanxing Duan 
supported by grants from the National Natural Science Foundation of China (No.82072699);the Natural Science Basic Research Program of Shaanxi Province,China (Nos.2023-JC-ZD-54 and 2017JM8165).
Objective:Pancreatic cancer is a highly malignant tumor of the digestive tract with a dismal prognosis.A key challenge of pancreatic cancer is its resistance to chemotherapy.The C-mesenchymal-epithelial transition fac...
关键词：CHEMORESISTANCE GEMCITABINE Pancreatic cancer RESVERATROL Synergistic effects 
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