supported by the Project of the Key Laboratory of Nano-imaging and Drug-loaded Preparation of Shanxi Province,China(No.202104010910010);the Project funded by China Postdoctoral Science Foundation(No.2022M722001);the Natural Science Foundation for Shanxi Province,China(No.202103021224241);the Special Fund from Medicinal Basic Research Innovation Center of Chronic Kidney Disease,Ministry of Education,Shanxi Medical University,China(No.CKD/SXMU-2024-11).
In this work,melanin nanoparticle-resveratrol(MNP-RES)nanosystem was excogitated and constructed for the treatment and imaging of folate-induced renal fibrosis(RF)mice model to fulfill the combination of diagnosis and...
financially supported by the National Natural Science Foundation of China(No.52225311);the Fundamental Research Funds for Central Universities.
Hair coloring has emerged as an integral part of the cosmetic industry,particularly in response to the increasing global aging phenomenon.The natural melanin analog,polydopamine(PDA),has garnered considerable attentio...
supported by the National Natural Science Foundation of China (Nos.81973410 and 82473537);the Independent Research Fund of Yunnan Characteristic Plant Extraction Laboratory (Nos.2022YKZY002 and 2022YKZY004)。
Nigella sativa L.seeds have been traditionally utilized in Chinese folk medicine for centuries to treat vitiligo.This study revealed that the ethanolic extract of Nigella sativa L.(HZC)enhances melanogenesis and mitig...
supported by the National Natural Science Foundation of China(Grant Nos.42288201&41922011);the Strategic Priority Research Program of the Chinese Academy of Sciences(Grant No.XDB26000000);the Fundamental Research Funds for the Central Universities(Grant No.0206-14380219)。
Mammalian hair,as a key feature related to endothermy,physical protection,and camouflage,has a long geohistorical record that dates back even to the Mesozoic.However,the limited information on the taphonomy of hair hi...
financially supported by National Natural Science Foundation of China(NSFC)(22007083);Wenzhou Major Science and Technology Innovation Project(ZZN2023002);the Fundamental Research Funds of Shengzhou Innovation Research Institute of Zhejiang Sci-Tech University(SYY2023B000004);the Fundamental Research Funds of Zhejiang Sci-Tech University(24262132-Y).
Skin aging is a systematic and complex process,mainly including intrinsic aging caused by time change and extrinsic aging caused by environmental factors.Photoaging caused by ultraviolet(UV)irradiation is the principl...
supported by National Natural Science Foundation of China(52225311);Sichuan Science and Technology Program(2024NSFSC1018);China Postdoctoral Science Foundation(2024M752208);Postdoctoral Fellowship Program of CPSF(GZC20241108);the Fundamental Research Funds for Central Universities。
Agents with robust ultraviolet(UV)absorption capabilities play a vital role in safeguarding organisms and inorganic materials from UV damage.Nonetheless,the synthetic procedures towards these UV absorbers are usually ...
supported by grants from the National Key R&D Program of China(2022YFD2400305);the Ear-marked Fund for Agriculture Seed Improvement Project of Shandong Province(2021ZLGX03,2022LZGCQY010,and 2020LZGC016);the China Agriculture Research System Project(CARS-49).
Mollusca exhibit remarkable diversity in shell coloration,attributed to the presence of melanin,a widely distributed pigment with various essential roles,such as mechanical strengthening,antioxidation and thermoregula...
supported by Shandong Province Agricultural Improved Seed Engineering Project (2019LZGC013);Shandong Province Key R&D Program (2021CXGC010806).
Albinism is a genetic disorder caused by a series of genetic abnormalities that result in a decrease in melanin.Golden yellow snakehead fish(GCAS)has been discovered while the Channa argus(CAS)breeding,but the genetic...
supported in part by the National Institutes of Health under award number K08CA255933.
SP100 is an antiviral protein that restricts the productive stage of human papillomavirus(HPV)and multiple other viruses,and viruses in turn block sUMO-1-mediated stabilization of SP100 and promotes its degradation(Ta...
supported by National Natural Science Foundation of China(grant nos.52225311 and 21975167)and the Fundamental Research Funds for Central Universities.
Due to the complexity of the structure within melanin and synthetic polymers(i.e.,polydopamine,PDA),it is a challenge to regulate the ultraviolet(UV)absorption.In nature,melanocytes can biosynthesize more pheomelanins...