supported in part by the National Institutes of Health under award number K08CA255933.
SP100 is an antiviral protein that restricts the productive stage of human papillomavirus(HPV)and multiple other viruses,and viruses in turn block sUMO-1-mediated stabilization of SP100 and promotes its degradation(Ta...
Primary biliary cholangitis(PBC)is a chronic cholestatic liver disease characterized by immune-driven destruction of small intrahepatic bile ducts leading a proportion of patients to hepatic failure over the years.Dia...
supported by grants from the Fundamental Research Funds for the Central Universities[grant number 16ykjc25];National Key R&D Program of China[grant number 2017YFC1308800];the Sun Yat-sen University Clinical Research 5010 Program[grant number 2016005].
Introduction With advances in technology,natural orifice transluminal endoscopic surgery(NOTES)has long been an ultimate clinical pursuit in minimally invasive surgery.The transanal total mesorectal excision(taTME)in ...
supported by the National Natural Science Foundation of China (81672028 and 81371788)。
Human cytomegalovirus(HCMV)is a double-strand DNA virus widely infected in human.Circular RNAs(circ RNAs)are non-coding RNAs with most functions of which keep unknown,and the effects of HCMV productive infection on ho...