MELANOGENESIS

作品数：38被引量：71H指数：5
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Ligustroside derived from Ligustrum japonicum inhibits melanogenesis via blocking the MAPK and PKA/CREB signaling pathways
《Asian Pacific Journal of Tropical Biomedicine》2025年第2期65-74,I0004,I0005,共12页Xian-Rong Zhou Fatih Karadeniz Jung Hwan Oh Youngwan Seo Chang-Suk Kong 
supported by the BB21plus funded by Busan Metropolitan City and Busan Techno Park,and the National Research Foundation of Korea(NRF)grant funded by the Korea government(MSIT)(No.NRF-2023R1A2C1006268 and RS-2023-00212560).
Objective:To investigate the anti-melanogenic potential of ligustroside isolated from Ligustrum japonicum.Methods:The cytotoxicity of ligustroside was tested via MTT assay.Furthermore,the effects of ligustroside on th...
关键词：Ligustrum japonicum Ligustroside MAPK MELANOGENESIS CREB PKA 
Anti-melanogenic properties of FBCC-EP850 derived from Carex pumila Thunb
《Asian Pacific Journal of Tropical Biomedicine》2024年第11期477-485,共9页Mirissa Hewage Dumindu Kavinda Jinkuk Park Nayeong Kim Yung Hyun Choi Gi-Young Kim 
supported by the Korea Environmental Industry&Technology Institute through Project to Make Multi-ministerial National Biological Research Resources more Advanced funded by Korea Ministry of Environment(RS-2021-KE001783).
Objective:To elucidate the anti-melanogenic potential of Carex pumila Thunb.extract(FBCC-EP850).Methods:A collection of 180 plant extracts was tested for inhibition of mushroom tyrosinase activity using an in vitro as...
关键词：Carex pumila Thunb. MELANOGENESIS TYROSINASE cAMP-CREB-MITF signaling 
Reverse thinking:Tumor nutritional therapy
《BMEMat(BioMedical Engineering Materials)》2024年第3期1-3,共3页Binbin Ding Ping'an Ma Abdulaziz A.Al Kheraif Jun Lin 
The Science and Technology Development Planning Project of jilin Province,Grant/Award Number:20220101070JC;The National Natural Science Foundation of China,Grant/Award Numbers:NSFC52102354,52102180,52372273;Researchers Supporting Project King Saud University(Saudi Arabia),Grant/Award Number:RSP2024R31。
Tumor cells often exhibit metabolic abnormalities to meet the needs of rapid proliferation,and targeting tumor metabolism has become one of the effective strategies for cancer treatment.However,most of the current met...
关键词：MELANOGENESIS metabolism reactivation nanomicelle nutrient delivery tumor nutritional therapy 
Examination of wnt signaling mediated melanin transport and shell color formation in Pacific oyster(Crassostrea gigas)
《Marine Life Science & Technology》2024年第3期488-501,共14页Yue Min Qi Li Hong Yu Shaojun Du 
supported by grants from the National Key R&D Program of China(2022YFD2400305);the Ear-marked Fund for Agriculture Seed Improvement Project of Shandong Province(2021ZLGX03,2022LZGCQY010,and 2020LZGC016);the China Agriculture Research System Project(CARS-49).
Mollusca exhibit remarkable diversity in shell coloration,attributed to the presence of melanin,a widely distributed pigment with various essential roles,such as mechanical strengthening,antioxidation and thermoregula...
关键词：MELANOGENESIS Melanosome trafficking WIF-1 
Advances in the function of traditional medicine for vitiligo treatment
《Traditional Medicine Research》2024年第3期43-51,共9页Jun Liu Jia-Yi Li Jing-Jing Xu Ling-Jun Li Wang Cheng Sheng-Tao Yuan Wei Zhang Hong-Yang Li 
supported by the National Natural Science Foundation of China(82003808);the Open Project of Jiangsu Provincial Science and Technology Resources(Clinical Resources)Coordination Service Platform(No.TC2022B015);the Shuangchuang Doctor Project of Jiangsu Province(No.JSSCBS20220147)。
Vitiligo has a significant impact on a substantial number of individuals worldwide.Traditional Chinese medicine has a long history of serving as a therapeutic treatment for vitiligo.Nevertheless,given the increasing v...
关键词：VITILIGO traditional Chinese medicine MELANOGENESIS 
Epimedin B exhibits pigmentation by increasing tyrosinase family proteins expression,activity,and stability被引量：1
《Journal of Pharmaceutical Analysis》2024年第1期69-85,共17页Chen Hong Yifan Zhang Lili Yang Haoyang Xu Kang Cheng Zhi Lv Kaixian Chen Yiming Li Huali Wu 
supported by the Open Project of National Major Science and Technology Infrastructure of Translational Medicine,China(Grant No.:TMSK-2021−404);the SIMM-SHUTCM Joint Innovation Research Program,China(2022);the Youth Innovation Research Foundation,China(Grant No.:A1-U21-205-01010109);the National Natural Science Foundation of China(Grant No.:81972932).
Epimedin B(EB)is one of the main flavonoid ingredients present in Epimedium brevicornum Maxim.,a traditional herb widely used in China.Our previous study showed that EB was a stronger inducer of melanogenesis and an a...
关键词：Epimedin B MELANOSOME TYROSINASE MELANOGENESIS 
Inhibitory effect of Cyrtomium falcatum on melanogenesis in α-MSH-stimulated B16F10 murine melanoma cells被引量：2
《Asian Pacific Journal of Tropical Biomedicine》2023年第9期403-410,共8页Xian-Rong Zhou Jung Hwan Oh Fatih Karadeniz Hyunjung Lee Hyo Eun Kim Migeon Jo Youngwan Seo Chang-Suk Kong 
This work was supported by the National Research Foundation of Korea(NRF)grant funded by the Korea government(MSIT)(No.2023R1A2C1006268 and RS-2023-00212560).
Objective:To explore the anti-melanogenic potential of Cyrtomium falcatum.Methods:The effects of Cyrtomium falcatum crude extract and its solvent fractions on tyrosinase activity,melanin content,and the expressions of...
关键词：Cyrtomium falcatum MELANOGENESIS Α-MSH B16F10 melanoma cells 
The tRNA-derived fragment tRF-5022a positively regulates melanogenesis
《Genes & Diseases》2023年第4期1203-1205,共3页Si Li Lan Zhang Jing Chen Ling Jiang Chuhan Fu Ao Huang Xinxin Lei Siyu Yang Qinghai Zeng Ke Cao 
supported by the National Natural Science Foundation of China(No.82103704);the Natural Science Foundation of Hunan Province(China)(No.2021JJ20089,2022JJ70148);Wisdom Accumulation and Talent Cultivation Project of the Third Xiangya Hospital of Central South Uni-versity,Hunan,China(No.YX202007);the Hunan Science and Technology Innovation Project(China)(No.2021RC3035).
The tRNA-derived fragments(tRFs)are small non-coding RNAs containing fewer than 50 nucleotides that are abundant in humans and have various biological functions.However,their roles and mechanisms in melanogenesis are ...
关键词：functions melan GENESIS 
MicroRNA-370-5p inhibits pigmentation and cell proliferation by downregulating mitogen-activated protein kinase kinase kinase 8 expression in sheep melanocytes
《Journal of Integrative Agriculture》2023年第4期1131-1141,共11页JI Kai-yuan WEN Ru-jun WANG Zheng-zhou TIAN Qian-qian ZHANG Wei ZHANG Yun-hai 
funded by the Natural Science Foundation of Anhui Province,China(2008085QC158);the University Natural Science Research Project of Anhui Province(KJ2019A0165)。
In mammals,microRNAs(miRNAs)play key roles in multiple biological processes by regulating the expression of target genes.Studies have found that the levels of miR-370-5p expression differ significantly in the skins of...
关键词：MICRORNA mitogen-activated protein kinase kinase kinase 8 MELANOGENESIS sheep melanocytes cell proliferation 
The mechanisms of melanogenesis inhibition by glabridin:molecular docking,PKA/MITF and MAPK/MITF pathways被引量：8
《Food Science and Human Wellness》2023年第1期212-222,共11页Chunxing Pan Xiaoying Liu Yating Zheng Zejun Zhang Yongliang Li Biao Che Guangrong Liu Lanyue Zhang Changzhi Dong Haji Akber Aisa Zhiyun Du Zhengqiang Yuan 
supported by the Inner Mongolia Autonomous Region Science and Technology Revitalization Foundation (2021CG0029);the National Natural Science Foundation of China (22178070)
Glabridin is the main ingredient of hydrophobic fraction in licorice extract and has been shown to have anti-melanogenesis activity in skins.However,the underlying mechanism(s)remain not completely understood.The aim ...
关键词：GLABRIDIN MELANOGENESIS Molecular docking PKA/MITF pathway MAPK/MITF pathway 
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