Reverse thinking:Tumor nutritional therapy  

作　　者：Binbin Ding Ping'an Ma Abdulaziz A.Al Kheraif Jun Lin 

机构地区：[1]State Key Laboratory of Rare Earth Resource Utilization,Changchun Institute of Applied Chemistry,Chinese Academy of Sciences,Changchun,China [2]School of Applied Chemistry and Engineering,University of Science and Technology of China,Hefei,China [3]Dental Health Department,College of Applied Medical Sciences,King Saud University,Riyadh,Saudi Arabia

出　　处：《BMEMat(BioMedical Engineering Materials)》2024年第3期1-3,共3页生物医学工程材料（英文）

基　　金：The Science and Technology Development Planning Project of jilin Province,Grant/Award Number:20220101070JC;The National Natural Science Foundation of China,Grant/Award Numbers:NSFC52102354,52102180,52372273;Researchers Supporting Project King Saud University(Saudi Arabia),Grant/Award Number:RSP2024R31。

摘　　要：Tumor cells often exhibit metabolic abnormalities to meet the needs of rapid proliferation,and targeting tumor metabolism has become one of the effective strategies for cancer treatment.However,most of the current methods targeting metabolism focus on inhibiting hyperactivated metabolic pathways,hindering their further application.A recent innovative work,proposed a nutrient-based strategy to reactivate metabolism for tumor therapy by targeting suppressed metabolic pathways.This approach through delivering nutrients to tumor cells directly using nanotechnology indicates that specific nutrients can serve as potent activators of metabolic pathways.As a new direction along the reverse thinking,this study suggests that this nutrient-based metabolism reactivation strategy will inspire broad applications in the treatment of other diseases associated with metabolic disorders,besides tumor.

关 键 词：MELANOGENESIS metabolism reactivation nanomicelle nutrient delivery tumor nutritional therapy 

分 类 号：R73[医药卫生—肿瘤]