GLABRIDIN

作品数：8被引量：18H指数：2
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Glabridin and gymnemic acid alleviates choroid structural change and choriocapillaris impairment in diabetic rat’s eyes
《World Journal of Diabetes》2025年第3期187-202,共16页Udomlak Matsathit Manaras Komolkriengkrai Wipapan Khimmaktong 
Supported by the Prince of Songkla University Research Fund,No.SCI6302040S。
BACKGROUND Small blood vessels in the eyes are more susceptible to injury,which can lead to complications.However,since diabetic retinopathy is often a serious clinical condition,most of this study focuses on the vasc...
关键词：Diabetes CHOROID Gymnemic acid GLABRIDIN Vascular endothelial growth factor Cluster of differentiation 31 CHORIOCAPILLARIS 
The mechanisms of melanogenesis inhibition by glabridin:molecular docking,PKA/MITF and MAPK/MITF pathways被引量：8
《Food Science and Human Wellness》2023年第1期212-222,共11页Chunxing Pan Xiaoying Liu Yating Zheng Zejun Zhang Yongliang Li Biao Che Guangrong Liu Lanyue Zhang Changzhi Dong Haji Akber Aisa Zhiyun Du Zhengqiang Yuan 
supported by the Inner Mongolia Autonomous Region Science and Technology Revitalization Foundation (2021CG0029);the National Natural Science Foundation of China (22178070)
Glabridin is the main ingredient of hydrophobic fraction in licorice extract and has been shown to have anti-melanogenesis activity in skins.However,the underlying mechanism(s)remain not completely understood.The aim ...
关键词：GLABRIDIN MELANOGENESIS Molecular docking PKA/MITF pathway MAPK/MITF pathway 
Chemical basis of pregnane X receptor activators in the herbal supplement Gancao (licorice)被引量：1
《Liver Research》2022年第4期251-257,共7页Anqi Cheng Saifei Lei Junjie Zhu Jie Lu Mary F.Paine Wen Xie Xiaochao Ma 
This work was supported by the USA National Center for Com-plementary and Integrative Health Grant R21AT011088(to X.Ma);in part by Grant U54AT008909(to M.F.Paine);in part by the USA National Institute of Allergy and Infectious Diseases Grant R01AI131983(to X.Ma);National Institute of Diabetes and Digestive and Kidney Diseases Grant R01DK126875(to X.Ma).
Background and aims:The herbal supplement Gancao,also known as licorice,belongs to the genus Glycyrrhiza and has been used worldwide for its hepatoprotective effect.Recent studies have raised concerns about potential ...
关键词：GANCAO LICORICE GLABRIDIN Pregnane X receptor(PXR) Cytochrome P4503A4(CYP3A4) Herb-drug interactions 
Glabridin and Anti-Non-Muscle Myosin IIA Therapy Disrupts Non-Small Cell Lung Carcinoma Motility被引量：1
《Advances in Lung Cancer》2021年第2期11-19,共9页Marie Kelly-Worden Amy Troesch Sarah Pruitt Ryan Rhodes Deavin Eviston 
Lung cancer is the leading cause of cancer related death in the United States killing over 130,000 people each year. While a combination of chemo and radiation therapy may be effective, surgery is still required for m...
关键词：Anti-Non-Muscle Myosin IIA Antibody Cell Migration GLABRIDIN Non-Small Cell Lung Carcinoma Wound Healing Assay 
Glabridin Relaxes Vascular Smooth Muscles by Activating BK_(Ca) Channels and Inhibiting Phosphodiesterase in Human Saphenous Vein被引量：2
《Current Medical Science》2021年第2期381-389,共9页Cengiz Giüven Ali Parlar 
The aim of the current study was to investigate the pharmacological activity of glabridinon the isolated human saphenous vein (SV) and explore the underlying mechanisms. Samples of patients' SVs were removed during by...
关键词：GLABRIDIN BKCa channels human saphenous vein(SV)grafts cyclic guanosine monophosphate(cGMP) protein kinase G(PKG) 
Molecular Dynamics Simulations and Steered Molecular Dynamics Simulations of Glabridin Bound to Wild Type and V30A Mutant Transthyretin： Ligand-linked Perturbation of Tertiary Conformation
《Chemical Research in Chinese Universities》2018年第6期995-1003,共9页YU Zhengfei HAN Jiarui LIU Ye ZHU Jingxuan TIAN Xiaopian HAN Weiwei 
Supported by the Major Scientific Research Projects of Jilin Province, China（No.20140203025NY） and the Natural Science Foundation of Jilin Province, China（No. 3B812C201465）.
Transthyretin（TTR）, as a tetrameric protein, functions as a neuroprotector. The native TTR homotetramer dissociates into dimers and monomers. Dimers and monomers self-assemble into amyloid fibrils, and this process ...
关键词：TRANSTHYRETIN GLABRIDIN Conformational change Molecular mechanics-poisson Boltzmann surface area（MM-PBSA） 
The effects of glycyrrhizic acid and glabridin in the regulation of CXCL5 inflammation gene on acceleration of wound healing被引量：1
《Asian Pacific Journal of Tropical Biomedicine》2016年第2期108-113,共6页Hong Yung Yip Melissa Su Wei Poh Yoke Yin Chia 
Support by the Exploratory Research Grants Scheme(ERGS/1/2012/STG08/TAYLOR/03/2),Ministry of Higher Education,Malaysia
Objective: To evaluate the anti-inflammatory property of both glycyrrhizic acid(GA)and glabridin in reducing inflammation to accelerate wound regeneration on 3T3-L1 and NIH-3T3 fibroblast cell lines.Methods: Cell prol...
关键词：WOUND HEALING Glycyrrhizic acid GLABRIDIN CXCL5 INFLAMMATION CELL proliferation CELL migration 
Isolation, Identification and Tyrosinase Inhibitory Activities of the Extractives from Allamanda cathartica被引量：5
《Natural Resources》2011年第3期167-172,共6页Kosei Yamauchi Tohru Mitsunaga Irmanida Batubara 
Tyrosinase inhibitory activity of the extractives from A. cathartica was examined and their new bioactivity and potent active compounds were identified. Five compounds, glabridin, new lignan, kaempferol, naringenin, a...
关键词：Allamanda c athartica TYROSINASE GLABRIDIN KAEMPFEROL NARINGENIN Allamandicin 
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