grants from the National Key Research and Development Program of China(2021YFC2100800);the National Natural Science Foundation of China(No.22108154,No.22138006,No.32171430,No.22278240);the Natural Science Foundation of Beijing Municipality(M21010,China);the Shuimu Tsinghua Scholar Program(2020SM097,China).
Yeast has been an indispensable host for synthesizing complex plant-derived naturalcompounds, yet the yields remained largely constrained. This limitation mainly arises from overlookingthe importance of cell and pathw...
Background:This study explores the relationship between endoplasmic reticulum(ER)stress and diabetes,particularly focusing on the impact of physical exercise on ER stress mechanisms and identifying potential therapeut...
funded by the National Natural Science Foundation of China(82204878).
Licorice,a perennial herb of Leguminosa,is one of the oldest and most widely used herbal medicines worldwide.Its distinct sweet flavor and rich medicinal value make it an integral component of traditional Chinese medi...
supported by National Natural Science Foundation of China(Grant Nos.:81891010/81891011,81725023,82003614,82173950,31770192,32070187,32161133003 and 82003681);China Postdoctoral Science Foundation(Grant No:2022T150029).
Currently,human health due to corona virus disease 2019(COVID-19)pandemic has been seriously threatened.The coronavirus severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)spike(S)protein plays a crucial role i...
Uncontrolled hyperglycemia or poorly managed disease increases the propensityfor a number of diabetes-related complications targeting major organs includingthe heart, eyes, and kidney. Although the mechanisms by which...
Supported by Inner Mongolia Mongolian Medicine Standardization Project(MB2019);Study on the Concoction Method of Licorice and Its Process(myxylxkky2019-04)。
[Objectives]To determine the improvement effect of vinegar soaked licorice on liver fibrosis induced by carbon tetrachloride(CCl_(4))combined with high-fat diet in rats.[Methods]Subcutaneous injection of 40%-60%CCl_(4...
supported by the Sichuan Famous Chinese Medicine Studio Construction Project.
Diabetes is a chronic disease characterized by hyperglycemia,of which type 2 diabetes mellitus(T2DM)accounts for about 95%[1].In addition,the prevalence of T2DM is still rising,seriously threatening human health.As th...
This work was supported by the USA National Center for Com-plementary and Integrative Health Grant R21AT011088(to X.Ma);in part by Grant U54AT008909(to M.F.Paine);in part by the USA National Institute of Allergy and Infectious Diseases Grant R01AI131983(to X.Ma);National Institute of Diabetes and Digestive and Kidney Diseases Grant R01DK126875(to X.Ma).
Background and aims:The herbal supplement Gancao,also known as licorice,belongs to the genus Glycyrrhiza and has been used worldwide for its hepatoprotective effect.Recent studies have raised concerns about potential ...
supported by National Natural Science Foundation of China(Nos.81891010/81891011,81725023,82003614,82173950,31770192,32070187 and 82003681);China Postdoctoral Science Foundation(2022T150029,China);the National Key Research and Development Program of China(No.2017-YFC1700405);the Science&Technology Department of Xinjiang Uygur Autonomous Region(2018AB012,China)。
It is an urgent demand worldwide to control the coronavirus disease 2019(COVID-19)pandemic caused by the severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)virus.The 3-chymotrypsin-like protease(3CL^(pro))and ...
financially supported by the National Key R and D Program of China(2018YFC1706500 and 2018YFC1707000)。
Objective:The aim of this study was to develop a reliable approach to simultaneously quantify 11 markers and explore the quality variation in honey-processed licorice.Materials and Methods:A high-performance liquid ch...