NARINGENIN

作品数:47被引量:247H指数:9
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相关领域:医药卫生生物学更多>>
相关作者:沈轶张婉玉冉丽杨秀伟姚祝军更多>>
相关机构:Tufts University美国德州大学北京大学浙江海洋大学更多>>
相关期刊:《Chinese Herbal Medicines》《国际眼科杂志》《Medicinal Plant》《Science China(Life Sciences)》更多>>
相关基金:国家自然科学基金广东省自然科学基金国家重点基础研究发展计划更多>>
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Oxidative stress mediates glycidol-induced endothelial injury and its protection by 6-C-(E-2-fluorostyryl)naringenin
《Food Science and Human Wellness》2024年第5期2584-2594,共11页Yue Zhou Hui Xu Ka-Wing Cheng Feng Chen Qian Zhou Mingfu Wang 
supported by the National Key R&D Program of China(2021YFD2100103);the National Natural Science Foundation of China(32101935).
Glycidol is a common lipid-derived foodborne toxicant mainly presents in refined oils and related foodstuffs.Vascular endothelial cells may be potential targets of the deleterious effects associated with glycidol expo...
关键词:GLYCIDOL Endothelial cells 6-C-(E-2-fluorostyryl)naringenin Oxidative stress Endothelial-to-mesenchymal transition 
Naringin and Naringenin:Potential Multi-Target Agents for Alzheimer’s Disease
《Current Medical Science》2024年第5期867-882,共16页Jing LU Jie CHEN Shu-yue LI Guang-jie PAN Yi OU Li-fu YUAN Jian-ping JIANG Ling-hui ZENG Jie ZHAO 
supported by the Joint Funds of the Zhejiang Provincial Natural Science Foundation of China(No.TGD23C050001);by National Natural Science Foundation of China(No.82074186).
Alzheimer’s disease(AD)is one of the most common forms of neurodegenerative dementia.The etiology of AD is multifactorial,and its complex pathophysiology involves tau and amyloid-βdeposition,increased oxidative stre...
关键词:Alzheimer’s disease NARINGIN NARINGENIN multitarget 
葡萄柚提取物柚皮素对运动性心肌损伤中铁死亡的调节作用
《分子植物育种》2024年第17期5825-5833,共9页邵语平 
甘肃省教育科学“十四五”规划课题项目(GS[2021]GHB1829)资助。
葡萄柚(Grapefruit)中含有丰富的无糖体柚皮素(aglycone naringenin,NAR),以其抗氧化、抗炎、抗癌、心血管保护和抗糖尿病的潜在效果而被广泛研究,它可以直接参与多种生物化学途径,调节酶活性和细胞信号传递。本研究旨在探索葡萄柚提取...
关键词:葡萄柚 无糖体柚皮素(aglycone naringenin NAR) 运动性心肌损伤 铁死亡 ROS/GSH/GPX4轴 心肌保护 
Unveiling osteoprotective potential of biologically active naringenin in rats with dexamethasone-induced osteoporosis
《Digital Chinese Medicine》2024年第2期171-183,共13页Tejal R.Waykar Satish K.Mandlik Deepa S.Mandlik 
Objective To investigate the protective effects of naringenin(NRG)against dexamethasone(DEX)-induced osteoporosis(OP)in rats.Methods Molecular docking of NRG was done with AutoDock Vina 1.2.0 software.Forty-eight fema...
关键词:NARINGENIN OSTEOPOROSIS DEXAMETHASONE Bone turnover markers Inflammatory cytokines 
Protective Effect of Naringenin on Acute Myocardial Ischemia-reperfusion Injury in Rats
《Medicinal Plant》2024年第3期50-52,共3页Xia ZHANG Ping ZHOU Juan LI Zhaojun XIANG Qianqian LUO Qing DENG 
[Objectives]To investigate the protective mechanism of naringenin on acute myocardial ischemia-reperfusion injury(AMI-RI)in Sprague-Dawley(SD)rats.[Methods]A total of 32 SD rats with AMI-RI model construction were ran...
关键词:Rat NARINGENIN Acute myocardial ISCHEMIA-REPERFUSION Lipid PEROXIDATION Inducible/endothelial NITRIC oxide SYNTHASE 
The WRKY46–MYC2 module plays a critical role in E-2-hexenal-induced anti-herbivore responses by promoting flavonoid accumulation
《Plant Communications》2024年第2期228-242,共15页Xin Hao Shuyao Wang Yu Fu Yahui Liu Hongyu Shen Libo Jiang Eric SMcLamore Yingbai Shen 
supported by the National Natural Science Foundation of China (31270655).
Volatile organic compounds(VOCs)play key roles in plant–plant communication,especially in response to pest attack.E-2-hexenal is an important component of VOCs,but it is unclear whether it can induce endog-enous plan...
关键词:E-2-hexenal early signaling events WRKY46–MYC2 RBOHD NARINGENIN 
The parallel biosynthesis routes of hyperoside from naringenin in Hypericum monogynum被引量:1
《Horticulture Research》2023年第9期247-259,共13页Yingying Wang Zhirong Cui Qianqian Li Shuai Zhang Yongyi Li Xueyan Li Lingyi Kong Jun Luo 
supported by the National Natural Science Foundation of China(No.32070389);the‘Double First-Class’University project of China Pharmaceutical University(CPU2022QZ29).
Hyperoside is a bioactive flavonoid galactoside in both medicinal and edible plants.It plays an important physiological role in the growth of flower buds.However,the hyperoside biosynthesis pathway has not been system...
关键词:INTERIOR concerning HYPER 
Naringenin suppresses NLRP3 inflammasome activation via the mRNA-208a signaling pathway in isoproterenol-induced myocardial infarction
《Asian Pacific Journal of Tropical Biomedicine》2023年第10期443-450,共8页Ayman Eldourghamy Toka Hossam Mohammed Abdalla Hussein Amal Abdel-Aziz Samir A.El-masry 
Objective:To investigate the cardioprotective effect of naringenin against isoproterenol(ISO)-induced cardiotoxicity in rats.Methods:Rats were divided into five groups:the normal group,the ISO group(85 mg/kg b.w.);the...
关键词:NARINGENIN ISOPROTERENOL Myocardial infarction Antioxidants NLRP3 mRNA-208a 
Naringenin inhibits lipid accumulation by activating the AMPK pathway in vivo and in vitro被引量:1
《Food Science and Human Wellness》2023年第4期1174-1183,共10页Xiaoyu Cai Songxue Wang Huali Wang Suwen Liu Guishan Liu Huibin Chen Ji Kang Hao Wang 
The aim of this study was to explore the lipid-lowering effect of naringenin and the underlying mechanism in high-fat-diet-fed SD rats and 3T3-L1 cells.In this study,SD rats were divided into the normal chow diet grou...
关键词:NARINGENIN Lipid accumulation Molecular docking 
海洋中药厚藤中柚皮素(naringenin)衍生物合成及胆碱酯酶抑制活性研究
《Journal of Chinese Pharmaceutical Sciences》2023年第8期636-644,共9页朱玉霞 张玲建 胡懿鸣 刘卫华 关丽萍 林琳 
Zhejiang Provincial University Student Science and Technology Innovation Activity Plan and New Seedling Talent Plan(Grant No.2021R411)。
本文以柚皮素(naringenin)为先导化合物,采用新药设计的原理,设计合成一系列查尔酮衍生物并对其进行AChE和BuChE的抑制活性研究。市售的邻羟基苯甲醛与丙烯醛在K2CO3催化下生成苯并吡喃-3-甲醛中间体。苯并吡喃-3-甲醛与取代的苯乙酮经...
关键词:厚藤 柚皮素 查尔酮衍生物 合成 胆碱酶抑制剂 
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