DEXAMETHASONE

作品数：367被引量：884H指数：13
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相关作者：沈耿杨任辉唐晶晶崔健超许志祥更多>>
相关机构：台湾大学南京医科大学北京大学中国医学科学院中国协和医科大学更多>>
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相关基金：国家自然科学基金中国博士后科学基金国家重点基础研究发展计划天津市自然科学基金更多>>
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High-dose dexamethasone regulates microglial polarization via the GR/JAK1/STAT3 signaling pathway after traumatic brain injury
《Neural Regeneration Research》2025年第9期2611-2623,共13页Mengshi Yang Miao Bai Yuan Zhuang Shenghua Lu Qianqian Ge Hao Li Yu Deng Hongbin Wu Xiaojian Xu Fei Niu Xinlong Dong Bin Zhang Baiyun Liu 
supported by research grants from the Ningbo Science and Technology Plan Project,No.2022Z143hezuo(to BL);the National Natural Science Foundation of China,No.82201520(to XD)。
Although microglial polarization and neuroinflammation are crucial cellular responses after traumatic brain injury,the fundamental regulatory and functional mechanisms remain insufficiently understood.As potent anti-i...
关键词：apoptosis BV2 microglia DEXAMETHASONE glucocorticoid receptor GLUCOCORTICOIDS innate immune system microglial polarization neuroinflammation primary microglia traumatic brain injury 
Effect of simultaneous intravitreal ranibizumab and extended-release dexamethasone injection on patients with naïve versus refractory retinal vein occlusion macular edema:a prospective,multicenter,and interventional open-label study
《International Journal of Ophthalmology(English edition)》2025年第5期860-867,共8页Yao-Yao Sun Jie Meng Shan-Shan Li Qin Xiao Tian-Zi Zhang Heng Miao Ming-Wei Zhao Hui-Jun Qi 
Supported by the National Nature Science Foundation of China(No.82301211);Beijing Natural Science Foundation(No.J230028).
AIM:To evaluate the efficacy and safety of concurrent intravitreal ranibizumab(IVR)and extended-release dexamethasone injections(Dex-I)in naïve and refractory patients with retinal vein occlusion macular edema(RVO-ME)...
关键词：retinal vein occlusion macular edema prospective clinical trial anti-vascular endothelial growth factor dexamethasone implant 
Dexamethasone intravitreal implant monotherapy in naive patients with macular edema secondary to retinal vein occlusion:long term follow-up retrospective cohort study
《International Journal of Ophthalmology(English edition)》2025年第5期876-882,共7页Gamze Karataş AkınÇakır Tahsin Uzundede Öznur Aday Ahmet MelihÖzoğuz Mehmet Egemen Karataş AslıKırmacıKabakcı 
AIM:To investigate the efficacy and safety of repeated dexamethasone implants with real-life data in eyes with naive retinal vein occlusion(RVO)with macular edema(ME)at a minimum of 60mo follow-up.METHODS:In this retr...
关键词：DEXAMETHASONE intravitreal naïve retinal vein occlusion macular edema 
Revisiting dexamethasone dosage in COVID-19 management
《World Journal of Virology》2025年第1期124-126,共3页Abhishet Varama 
The ongoing coronavirus disease 2019(COVID-19)pandemic has necessitated rapid advancements in therapeutic strategies,with dexamethasone emerging as a key treatment for severe cases.This editorial discusses the systema...
关键词：COVID-19 treatment Dexamethasone dosage Personalized medicine EDITORIAL Clinical adaptability 
Dexamethasone in coronavirus disease 2019 care:Dosage and utilization insights
《World Journal of Virology》2025年第1期1-4,共4页Laiba Shamim Imshaal Musharaf Abdulqadir J Nashwan 
Coronavirus disease 2019(COVID-19)is a contagious disease caused by severe acute respiratory syndrome coronavirus 2.It was declared a global pandemic on March 11,2020,by the World Health Organization.An excessive infl...
关键词：COVID-19 Severe acute respiratory syndrome CORTICOSTEROID DEXAMETHASONE ANTI-INFLAMMATORY 
Intraperitoneal Instillation of Dexmedetomidine vs Dexamethasone as Adjuvant to Bupivacaine for Postoperative Pain in Laparoscopic Cholecystectomy, a Randomized Clinical Trial
《Open Journal of Anesthesiology》2025年第1期1-12,共12页Ayman Mohamady Eldemrdash Zaher Z. Zaher Tarek S. Hemaida Taha T. Dardeer Hani M. Raslan Shawky M. Abdelgalil Mohmed R. Saad Mohammed S. Aly 
Background: Intraperitoneal instillation (IPI) of local anesthesia was reported to reduce postoperative pain after laparoscopic surgeries. We aim to evaluate the effectiveness of IPI of bupivacaine + dexmedetomidine v...
关键词：BUPIVACAINE DEXMEDETOMIDINE DEXAMETHASONE Laparoscopic Cholecystectomy 
Improving dexamethasone drug loading and efficacy in treating rheumatoid arthritis via liposome:Focusing on inflammation and molecular mechanisms
《Animal Models and Experimental Medicine》2025年第1期5-19,共15页Mohammad Yasin Zamanian Hamidreza Zafari Maria K.Osminina Alla A.Skakodub Raed Fanoukh Aboqader Al-Aouadi Maryam Golmohammadi Nikta Nikbakht Iman Fatemi 
Rheumatoid arthritis(RA)is a chronic autoimmune disease that affects approxi-mately 0.46%of the global population.Conventional therapeutics for RA,including disease-modifying antirheumatic drugs(DMARDs),nonsteroidal a...
关键词：DEXAMETHASONE INFLAMMATION LIPOSOME rheumatoid arthritis TNF-α 
Enhancing global hepatocellular carcinoma management:Bridging Eastern and Western perspectives on dexamethasone and Nacetylcysteine before transarterial chemoembolization
《World Journal of Gastroenterology》2024年第47期4983-4990,共8页Thang Viet Luong Nam Van Duc Nguyen Linh Duy Le Hieu Nguyen Hoang Minh Hai Nguyen Ngoc Dang 
This article explores the integration of Eastern and Western perspectives on the use of dexamethasone and N-acetylcysteine as premedications in transarterial chemoembolization for hepatocellular carcinoma(HCC).By exam...
关键词：Hepatocellular carcinoma Transarterial chemoembolization DEXAMETHASONE N-ACETYLCYSTEINE East-West perspectives Post-embolization syndrome 
Optical Coherence Tomography (OCT) Feature Identifying Niche for Dexamethasone (FIND) Intravitreal Implant in the Treatment of Anti-VEGF Slow Responders with Diabetic Macular Edema
《Open Journal of Ophthalmology》2024年第4期398-404,共7页Ram Peddada Joshua C. Hollingsworth David Redden Eric Marin 
This paper raises the question if intravitreal dexamethasone implant deserves to be utilized more effectively in a select subset of eyes with diabetic macular edema (DME). If so, what is the OCT morphology of such eye...
关键词：Diabetic Macular Edema Dexamethasone Intravitreal Implant ANTI-VEGF FIND OCT Morphology 
Dengue hemorhagic fever associated hemophagocytc lymphohistiocytosis in primigravida:A case report
《Asian Pacific Journal of Tropical Medicine》2024年第12期563-567,共5页Pyrus Bhellum Rishabh Bora Bharat Kumar Rakesh Kumar 
Rationale:Hemophagocytic lymphohistiocytosis(HLH)is a rare but severe complication of dengue virus infection,associated with high mortality.We report a case of a 9-week primigravida presenting with high grade fever sp...
关键词：Dengue haemorrhagic fever Hemophagocytic lymphohistiocytosis HLH Pregnant female DEXAMETHASONE 
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