DEXMEDETOMIDINE

作品数:172被引量:521H指数:13
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相关领域:医药卫生更多>>
相关作者:徐永明杜冬萍江伟冯艺王晓宁更多>>
相关机构:重庆医科大学华中农业大学温州医科大学国立中兴大学更多>>
相关期刊:更多>>
相关基金:国家自然科学基金中国博士后科学基金国家重点基础研究发展计划天津市自然科学基金更多>>
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Construction of a risk prediction model for postoperative cognitive dysfunction in colorectal cancer patients
《World Journal of Gastrointestinal Surgery》2025年第4期221-232,共12页Zhen-Ping Zheng Yong-Guo Zhang Ming-Bo Long Kui-Quan Ji Jin-Yan Peng Kai He 
Supported by the Research Fund of Qiannan Medical College for Nationalities,No.Qnyz202222.
BACKGROUND Colorectal cancer(CRC)is one of the most prevalent and lethal malignant tumors worldwide.Currently,surgical intervention was the primary treatment modality for CRC.However,increasing studies have revealed t...
关键词:Colorectal cancer POSTOPERATIVE Cognitive dysfunction ANESTHESIA Risk prediction model DEXMEDETOMIDINE Preventive value 
Perioperative neurocognitive dysfunction and role of dexmedetomidine in radical colon cancer surgery in elderly patients
《World Journal of Gastrointestinal Surgery》2025年第3期6-13,共8页Chandra K Pandey Abhishek Kumar 
This article explored the application of dexmedetomidine(Dex),a highly selective alpha-2 agonist,in managing postoperative cognitive dysfunction(POCD)in elderly patients undergoing radical colon cancer surgery.Aging i...
关键词:Colon cancer DEXMEDETOMIDINE General anesthesia ELDERLY Radical colon cancer surgery Cognitive function 
Analgesic effect and safety of dexmedetomidine-assisted intravenous-inhalation combined general anesthesia in laparoscopic minimally invasive inguinal hernia surgery
《World Journal of Gastrointestinal Surgery》2025年第3期161-170,共10页Qian-Xing Lou Ke-Ping Xu 
BACKGROUND Currently,very few studies have examined the analgesic effectiveness and safety of dexmedetomidine-assisted intravenous-inhalation combined general anesthesia in laparoscopic minimally invasive surgery for ...
关键词:DEXMEDETOMIDINE Intravenous-inhalation combined general anesthesia Inguinal hernia Laparoscopic minimally invasive surgery Analgesia SAFETY 
Intraoperative targeted blood pressure management and dexmedetomidine on composite complications in moderate-to-high risk patients after major abdominal surgery
《Chinese Medical Journal》2025年第2期240-242,共3页Qiongfang Wu Haifeng Wang Meilin Li Wenjun Hu Shuting He Yanling Sun Dongliang Mu Daniel ISessler Dongxin Wang 
supported by grants from the National Key Research&Development Program of China(Nos.2023YFC2506900 and 2018YFC2001800);the National High Level Hospital Clinical Research Funding(Nos.2022CR74 and 2022CR78 of Peking University First Hos pital);Braun Anesthesia Scientific Research Fund(No.BBDF-2019-004).
To the Editor:Postoperative organ injuries and complications are the leading causes of perioperative morbidity and mortality.Although many retrospective studies have revealed the association between intraoperative hyp...
关键词:major abdominal surgery composite complications tight blood pressure management DEXMEDETOMIDINE prospective randomized trials intraoperative blood pressure management moderate high risk patients retrospective studies 
Intraperitoneal Instillation of Dexmedetomidine vs Dexamethasone as Adjuvant to Bupivacaine for Postoperative Pain in Laparoscopic Cholecystectomy, a Randomized Clinical Trial
《Open Journal of Anesthesiology》2025年第1期1-12,共12页Ayman Mohamady Eldemrdash Zaher Z. Zaher Tarek S. Hemaida Taha T. Dardeer Hani M. Raslan Shawky M. Abdelgalil Mohmed R. Saad Mohammed S. Aly 
Background: Intraperitoneal instillation (IPI) of local anesthesia was reported to reduce postoperative pain after laparoscopic surgeries. We aim to evaluate the effectiveness of IPI of bupivacaine + dexmedetomidine v...
关键词:BUPIVACAINE DEXMEDETOMIDINE DEXAMETHASONE Laparoscopic Cholecystectomy 
Study on the Effect of Mindfulness-Based Stress Reduction Combined with Preemptive Sedation on Postoperative Sleep Improvement in Patients Undergoing Gynecological Laparoscopic Surgery
《Journal of Clinical and Nursing Research》2024年第12期357-362,共6页Liyan Chen Liming Zhao Honghua Lei Qingyou Liang Zhiyu Xin 
Researcher Funding from Shaoguan City“Clinical Study on the Impact of Mindfulness-Based Stress Reduction Combined with Preemptive Sedation on Stress in Gynecological Laparoscopic Surgery”(Project No.220514194530401)。
Objective:To explore the effects of mindfulness-based stress reduction(MBSR)training combined with dexmedetomidine hydrochloride preemptive sedation on postoperative sleep quality in patients undergoing laparoscopic o...
关键词:Mindfulness-based stress reduction Dexmedetomidine hydrochloride Laparoscopic surgery Sleep quality Stress response 
Dexmedetomidine in colon cancer surgery:Evaluating its impact and efficacy
《World Journal of Gastrointestinal Surgery》2024年第12期3663-3665,共3页Sohan Lal Solanki Jyoti Sharma 
We present an editorial on an article that highlights the benefits of dexmedeto-midine(Dex)in colon cancer surgeries,which have been thoroughly investigated in the referenced publication involving 117 subjects.Of thes...
关键词:Colon cancer DEXMEDETOMIDINE IMPACT Human studies Animal models In vitro studies 
Cognitive clarity in colon surgery: The dexmedetomidine advantage
《World Journal of Gastrointestinal Surgery》2024年第11期3629-3631,共3页Asad G Rao Abdulqadir J Nashwan 
Colon cancer is one of the most prevalent cancers globally,especially in the older age group.A large number of older patients undergoing surgery for colon cancer suffer from postoperative cognitive dysfunction(POCD).T...
关键词:DEXMEDETOMIDINE Colon cancer Old age group Postoperative cognitive dysfunction Cerebral injury 
Dexmedetomidine ameliorates diabetic intestinal injury by promoting the polarization of M2 macrophages through the MMP23B pathway
《World Journal of Diabetes》2024年第9期1962-1978,共17页Man Lu Xiao-Wen Guo Fang-Fang Zhang Dan-Hong Wu Di Xie Feng-Qin Luo 
BACKGROUND Diabetes is often associated with gastrointestinal dysfunctions,which can lead to hypoglycemia.Dexmedetomidine(DEX)is a commonly used sedative in perioperative diabetic patients and may affect gastrointesti...
关键词:DIABETES DEXMEDETOMIDINE Intestinal barrier Piezo1 Tight junctions 
Impact of dexmedetomidine-assisted anesthesia in elderly patients undergoing radical resection of colon cancer
《World Journal of Gastrointestinal Surgery》2024年第9期2925-2933,共9页Xiao-Peng Tian Hui-Min Bu Hong-Yan Ma Min Zhao 
BACKGROUND Radical resection of colon cancer under general anesthesia is one of the main treatment methods for this malignancy.However,due to the physiological charac-teristics of elderly patients,the safety of periop...
关键词:DEXMEDETOMIDINE General anesthesia ELDERLY Colon cancer radical surgery Anesthesia effectiveness DELIRIUM Cellular immunity 
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