Cognitive clarity in colon surgery: The dexmedetomidine advantage  

作　　者：Asad G Rao Abdulqadir J Nashwan 

机构地区：[1]Department of Clinical Medicine,Dow Medical College,Karachi 74200,Pakistan [2]Department of Nursing and Midwifery Research,Hamad Medical Corporation,Doha 3050,Qatar

出　　处：《World Journal of Gastrointestinal Surgery》2024年第11期3629-3631,共3页世界胃肠外科杂志（英文）

摘　　要：Colon cancer is one of the most prevalent cancers globally,especially in the older age group.A large number of older patients undergoing surgery for colon cancer suffer from postoperative cognitive dysfunction(POCD).The trial by Bu et al demonstrated that dexmedetomidine(Dex)significantly reduced the incidence of POCD compared to placebo in individuals undergoing colon cancer surgery.Additionally,better cerebral oxygenation and lower cerebral injury markers were reported with the use of Dex.The trial has some limitations,such as a single-center design and a smaller sample size,and further studies with larger patient populations and robust multi-center designs are warranted to establish these findings.

关 键 词：DEXMEDETOMIDINE Colon cancer Old age group Postoperative cognitive dysfunction Cerebral injury 

分 类 号：R656.9[医药卫生—外科学]