GLUCOCORTICOIDS

作品数：190被引量：656H指数：12
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High-dose dexamethasone regulates microglial polarization via the GR/JAK1/STAT3 signaling pathway after traumatic brain injury
《Neural Regeneration Research》2025年第9期2611-2623,共13页Mengshi Yang Miao Bai Yuan Zhuang Shenghua Lu Qianqian Ge Hao Li Yu Deng Hongbin Wu Xiaojian Xu Fei Niu Xinlong Dong Bin Zhang Baiyun Liu 
supported by research grants from the Ningbo Science and Technology Plan Project,No.2022Z143hezuo(to BL);the National Natural Science Foundation of China,No.82201520(to XD)。
Although microglial polarization and neuroinflammation are crucial cellular responses after traumatic brain injury,the fundamental regulatory and functional mechanisms remain insufficiently understood.As potent anti-i...
关键词：apoptosis BV2 microglia DEXAMETHASONE glucocorticoid receptor GLUCOCORTICOIDS innate immune system microglial polarization neuroinflammation primary microglia traumatic brain injury 
Correction to:Pollution characteristics and ecological risk assessment of glucocorticoids in the Jiangsu section of the Yangtze River Basin
《Frontiers of Environmental Science & Engineering》2025年第4期213-213,共1页
Tau is a receptor with low affinity for glucocorticoids and is required for glucocorticoid-induced bone loss
《Cell Research》2025年第1期23-44,共22页Wenyu Fu Meng Chen Kaidi Wang Yujianan Chen Yazhou Cui Yangli Xie Zi-Ning Lei Wenhuo Hu Guodong Sun Guiwu Huang Chaopeng He Jackie Fretz Aubryanna Hettinghouse Ronghan Liu Xianyi Cai Mingshuang Zhang Yuehong Chen Nan Jiang Minchun He Daniel HWiznia Huiyun Xu Zhe-Sheng Chen Lin Chen Kanglai Tang Hong Zhou Chuan-Ju Liu 
supported partly by NIH research grants R01AR062207,R01AR061484,R01AR076900,R01AR078035 and R01NS070328.
Glucocorticoids(GCs)are the most prescribed anti-inflammatory and immunosuppressive drugs.However,their use is often limited by substantial side effects,such as GC-induced osteoporosis(GIO)with the underlying mechanis...
关键词：drugs PRESCRIBED AFFINITY 
Glucocorticoid therapy for acute respiratory distress syndrome:Currentconcepts被引量：2
《Journal of Intensive Medicine》2024年第4期417-432,共16页Yuanrui Zhao Zhun Yao Song Xu Lan Yao Zhui Yu 
Acute respiratory distress syndrome(ARDS),a fatal critical disease,is induced by various insults.ARDS represents a major global public health burden,and the management of ARDS continues to challenge healthcaresystems ...
关键词：Acute respiratory distress syndrome GLUCOCORTICOIDS STEROIDS COVID-19 Clinical trials HETEROGENEITY 
Blind date:female fossorial amphisbaenians prefer scent marks of large and healthy males
《Integrative Zoology》2024年第6期1018-1033,共16页JoséMARTÍN Gonzalo RODRIGUEZ-RUIZ Álvaro NAVARRO-CASTILLA Isabel BARJA Pilar LOPEZ 
supported by the Spanish Ministerio de Ciencia,Innovación y Universidades grant PGC2018-093592-B-I00(MCIU/AEI/FEDER,UE);by the Ministerio de Ciencia e Innovación grant PID2021-122358NB-I00(MCIN/AEI/10.13039/501100011033 and ERDF A way of making Europe).
Selecting a good mate is a decision with importantfitness consequences.For this reason,mate choice has promotedthe evolution of sexual ornaments signaling the quality of an individual.In fossorial animals,inhabiting vi...
关键词：amphisbaenian Blanus cinereus chemical signals GLUCOCORTICOIDS health state mate choice 
Characteristics and Risk Factors of Infections among Patients with Autoimmune Bullous Diseases: A Retrospective Single-Center Study in China
《Infectious Diseases & Immunity》2024年第4期170-177,共8页Feiran Zhou Xiaoping Zheng Yixuan Yang Qingluan Yang Jingyu Zhou Haoxin Xu Xiaoqun Luo Lingyun Shao Wenhong Zhang Zhonghua Li Qiaoling Ruan 
supported by National Natural Science Foundation of China(82271794 and 82302533);Shanghai Science and Technology Commission sailing project(22YF1404900).
Background: Since infections can lead to adverse outcomes in autoimmune bullous diseases (AIBD), this study aimed to analyze infection characteristics in AIBD, predict infection risk factors and provide probable sugge...
关键词：PEMPHIGUS Bullous pemphigoid GLUCOCORTICOIDS INFECTIONS Retrospective studies 
激素不同给药途径治疗突发性聋疗效观察
《中国耳鼻咽喉头颈外科》2024年第11期742-744,共3页张晓红 鄢胜刚 高宇阳 
2024年浙江省中医药科技计划项目(2024ZF163)。
目的观察激素不同给药途径治疗突发性聋的疗效。方法回顾性分析海宁市中医院2021年4月~2024年4月间90例(90耳)突发性聋患者的病历资料,根据糖皮质激素用药方案分为静脉注射组26例(26耳)、鼓室注射组31例(31耳)、耳后注射组33例(33耳),...
关键词：耳聋(Deafness) 糖皮质激素类(Glucocorticoids) 投药途径(Drug Administration Routes) 注射 静脉内(Injections Intravenous) 鼓室注射(injection of tympanic cavity) 耳后注射(postauricular injection) 
Pollution characteristics and ecological risk assessment of glucocorticoids in the Jiangsu section of the Yangtze River Basin
《Frontiers of Environmental Science & Engineering》2024年第11期159-168,共10页Lichao Tan Keke Xu Shengxin Zhang Fukai Tang Mingzhu Zhang Feng Ge Kegui Zhang 
supported by the Natural Science Fund for Young Scholars of Jiangsu Province,China(No.BK20230118);the Special Fund of Chinese Central Government for Basic Scientific Research Operations in Commonweal Research Institute(No.GYZX220302);the Fund by the Institute of Carbon Peaking&Carbon Neutrality of Nanjing Institute of Environmental Sciences(Nos.ZX2023SZY058 and ZX2024SZY054).
Glucocorticoids,which are one of the most extensively used steroid hormones,are typical endocrine disruptors.In recent years,glucocorticoids have been widely detected in surface waters such as rivers and lakes,but the...
关键词：Yangtze River Basin GLUCOCORTICOIDS Pollution characteristics Ecological risk assessment 
Analysis of Tacrolimus Combined with Glucocorticoids for Refractory Nephrotic Syndrome
《Journal of Clinical and Nursing Research》2024年第11期147-153,共7页Guoxing An Xueyan Han 
Wuwei City Science and Technology Plan Project“Efficacy Analysis of Tacrolimus Combined with Glucocorticoids in the Treatment of Refractory Nephrotic Syndrome”(Project No.WW2101161)。
Objective:To analyze changes in liver and kidney function and lipid metabolism in patients with refractory nephrotic syndrome(RNS)after receiving different treatments.Methods:A total of 64 patients treated in the Wuwe...
关键词：Nephrotic syndrome REFRACTORY TACROLIMUS GLUCOCORTICOIDS Kidney function 
Combination treatment with telitacicept,mycophenolate mofetil and glucocorticoids for immunoglobulin A nephropathy:A case report
《World Journal of Clinical Cases》2024年第29期6307-6313,共7页Yan Shen Jin Yuan Shuang Chen Yong-Feng Zhang Ling Yin Qin Hong Yan Zha 
BACKGROUND Telitacicept reduces B cell activation and abnormal immunoglobulin A(IgA)antibody production by inhibiting the activity of B lymphocyte stimulator(BLyS)and a proliferation-inducing ligand(APRIL),thereby dec...
关键词：IgA nephropathy Telitacicept Mycophenolate mofetil GLUCOCORTICOIDS Case report 
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