云南高校图书馆联盟文献共享服务平台- TACROLIMUS

TACROLIMUS: 作品数：182被引量：653H指数：10; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：吴永贵齐向明杨辉王玮张小东更多>>; 相关机构：首都医科大学附属北京朝阳医院安徽医科大学第一附属医院台湾大学复旦大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金中国博士后科学基金国家科技支撑计划国家高技术研究发展计划更多>>

Mild diarrhea leading to tacrolimus toxicity in an immunocompromised patient with suspected community-acquired pneumonia:a case report: 《World Journal of Emergency Medicine》2025年第2期174-176,共3页Xueying Chen Jianbo Ding Jiali Zhang Hongyan Jiang Haibin Dai Lingyan Yu; supported by the Clinical Research Foundation of Zhejiang Provincial Medical Association (2020ZYC-A113)。; Tacrolimus (TAC) is increasingly used for immunosuppression in organ transplantation,dermatomyositis/polymyositis,and myasthenia gravis(MG) patients.^([1]) TAC has a narrow therapeutic window with overexposure leading...; 关键词：DIARRHEA PNEUMONIA GRAVIS

Tacrolimus induces insulin receptor substrate 1 hyperphosphorylation and inhibits mTORc1/S6K1 cascade in HL7702 cells: 《World Journal of Diabetes》2025年第2期175-182,共8页Hao-Yan Li Yi Wang Min Ran Fei Gao Bo-Yu Zhu Hai-Ying Xiao Chun Xu; BACKGROUND Tacrolimus(FK506)is a key calcineurin inhibitor used to prevent organ transplant rejection and is effective in improving graft survival.However,it is linked to hyperglycemia and insulin resistance,contribut...; 关键词：TACROLIMUS Insulin resistance DYSLIPIDEMIA Ribosomal protein S6 kinase beta-1 Glucose metabolism

Predictive value of tacrolimus concentration/dose ratio in first posttransplant week for CYP3A5-polymorphism in kidney-transplant recipients: 《World Journal of Transplantation》2025年第2期197-204,共8页Pham-Thai Dung Hoang-Xuan Su Nguyen-Chi Tue Nguyen-Huu Ben Nguyen-Minh Phuong Tuan-Ngoc Tran Phan-Ba Nghia Diem-Thi Van Nguyen Thi-Thuy Dung Hoang-Trung Vinh Lionel Rostaing Pham-Quoc Toan; Supported by the Vietnam National Foundation for Science and Technology Development,No.NAFOSTED 04/2020/TN.; BACKGROUND Tacrolimus(TAC)is metabolized primarily by the CYP3A-encoded enzyme family(CYP3A4,CYP3A5,and CYP3A7).Individuals expressing the CYP3A51 allele are considered fast metabolizers and generally require higher T...; 关键词：TACROLIMUS CYP3A5 Renal transplant recipient Concentration-to-dose Kidney transplant

A functional tacrolimus-releasing nerve wrap for enhancing nerve regeneration following surgical nerve repair: 《Neural Regeneration Research》2025年第1期291-304,共14页Simeon C.Daeschler Katelyn J.W.So Konstantin Feinberg Marina Manoraj Jenny Cheung Jennifer Zhang Kaveh Mirmoeini JPaul Santerre Tessa Gordon Gregory HBorschel; supported by the German Research Foundation(DA 2255/1-1;to SCD);a SickKids Research Training Competition(RESTRACOMP)Graduate Scholarship(to KJWS);an Ontario Graduate Scholarship(to KJWS);a grant from Natural Sciences and Engineering Research Council of Canada(NSERC)(to KJWS);a Kickstarter grant from the Institute of Biomedical Engineering(BME)at the University of Toronto(to KJWS);the Abe Frank Fund from the Riley’s Children Foundation(GHB)。; Axonal regeneration following surgical nerve repair is slow and often incomplete,resulting in poor functional recovery which sometimes contributes to lifelong disability.Currently,there are no FDA-approved therapies a...; 关键词：BIODEGRADABLE local drug delivery nerve injury nerve regeneration nerve wrap TACROLIMUS

Efficacy of mycophenolate mofetil combined with topical 0.05%tacrolimus in high-risk keratoplasty:1-year cohort study: 《International Journal of Ophthalmology(English edition)》2024年第12期2229-2235,共7页Jin-Yu Zhang Kang Yu Xiu-Ying Jiang Jia-Xin Liang Shi-You Zhou; Supported by Natural Science Foundation of Guangdong Province,China(No.2022A1515011140);China Postdoctoral Science Foundation(No.2023M744071);the Postdoctoral Fellowship Program of China Postdoctoral Science Foundation(No.GZB20230901);Regional Consolidated Fund-Youth Fund Project(No.2023A1515110531);Science and Technology Program of Guangzhou,China(No.202201020502).; AIM:To investigate the efficacy of systemic mycophenolate mofetil(MMF)as an adjunct in combination with topical tacrolimus(FK506)and corticosteroid eyedrops for preventing corneal graft rejection after high-risk kerat...; 关键词：IMMUNOSUPPRESSANTS high-risk keratoplasty mycophenolate mofetil

Analysis of Tacrolimus Combined with Glucocorticoids for Refractory Nephrotic Syndrome: 《Journal of Clinical and Nursing Research》2024年第11期147-153,共7页Guoxing An Xueyan Han; Wuwei City Science and Technology Plan Project“Efficacy Analysis of Tacrolimus Combined with Glucocorticoids in the Treatment of Refractory Nephrotic Syndrome”(Project No.WW2101161)。; Objective:To analyze changes in liver and kidney function and lipid metabolism in patients with refractory nephrotic syndrome(RNS)after receiving different treatments.Methods:A total of 64 patients treated in the Wuwe...; 关键词：Nephrotic syndrome REFRACTORY TACROLIMUS GLUCOCORTICOIDS Kidney function

Restoration of HMGCS2-mediated ketogenesis alleviates tacrolimus-induced hepatic lipid metabolism disorder: 《Acta Pharmacologica Sinica》2024年第9期1898-1911,共14页Sen-lin Li Hong Zhou Jia Liu Jian Yang Li Jiang Hui-min Yuan Meng-heng Wang Ke-shan Yang Ming Xiang; National Natural Science Foundation of China(No.82071749,81703630)。; Tacrolimus,one of the macrolide calcineurin inhibitors,is the most frequently used immunosuppressant after transplantation.Long-term administration of tacrolimus leads to dyslipidemia and affects liver lipid metabolis...; 关键词：fatty acid oxidation FKBP51-FoxO1 complex HMGCS2 KETOGENESIS mitochondrial protein acetylation TACROLIMUS

Tacrolimus may play a role in dermatitis and radiation-induced skin injury through cellular senescence: 《Radiation Medicine and Protection》2024年第3期161-164,共4页Jie Chen Ling Gao; supported by the Beijing Municipal Natural Science Foundation(7202139 and 7162137),China.; Skin Exposure of skin to ionizing radiation can induce acute or chronic biological effects,resulting in radiation-induced skin injury(RSI).Premature cellular senescence,caused by oxidative stress and/or DNA damage fro...; 关键词：TACROLIMUS Premature cellular senescence Radiation-induced skin injury p38 MAPK NF-κB

Exploring the impact of tacrolimus on kidney transplant recipients:insights into immunological outcomes: 《Journal of Chinese Pharmaceutical Sciences》2024年第8期737-750,共14页Zainab A Abbood Ahmed Hamza AL-Shammari Eman M.Jasim Amjad I.Oraibi; To minimize graft rejection,it is crucial to reduce immunosuppression.In the present study,we investigated immunological markers in the blood of transplant patients who did not receive tacrolimus.We also assessed allo...; 关键词：TACROLIMUS KIDNEY TRANSPLANT Immune system REJECTION

Correlations between serum kidney injury molecule-1,cystatin C and immunosuppressants:A cross-sectional study of renal transplant patients in Bahrain: 《Journal of Biomedical Research》2024年第3期269-277,共9页Kannan Sridharan Shamik Shah Mona Al Hammad Fatima Ali Mohammed Sindhan Veeramuthu Mona Abdulla Taher Mustafa Mohamed Hammad Lamees Jawad Eman Farid; Part of the consumables used in the present study was obtained as a part of funding of a research study from College of Medicine and Medical Sciences,Arabian Gulf University(Grant No.G05/AGU-11/19).; Renal transplant patients receive several immunosuppressive drug regimens that are potentially nephrotoxic for treatment.Serum creatinine is the standard for monitoring kidney function;however,cystatin C(Cys C)and kid...; 关键词：KIM-1 cystatin C mycophenolate mofetil TACROLIMUS EVEROLIMUS SIROLIMUS CYCLOSPORINE

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