SIROLIMUS

作品数:86被引量:229H指数:8
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相关领域:医药卫生更多>>
相关作者:周颖齐民夏永辉黄莹莹徐克更多>>
相关机构:中山大学江苏省人民医院华中科技大学中国医科大学附属第一医院更多>>
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相关基金:国家自然科学基金广东省自然科学基金国家科技支撑计划福建省自然科学基金更多>>
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Advances in gastrointestinal vascular bleeding disorders:Successful sirolimus treatment in colonic angioectasia
《World Journal of Gastroenterology》2025年第4期123-136,共14页Qi Sun Xiao-Ying Wang Dong-Hao Li Bai-Rong Li Xin-Zhuo Tu Zhi-Meng Jiang Shou-Bin Ning Tao Sun 
Air Force Medical Center Youth Talent Program Project,No.22YXQN034;Capital Health Development Research Special Project,No.2020-4-5123;Beijing Haidian District Health and Wellness Development Scientific Research Cultivation Program,No.HP2021-03-80803.
BACKGROUND Gastrointestinal(GI)vascular bleeding disorders pose significant clinical challenges due to their complex pathogenesis and varied treatment responses.Despite advancements in diagnostic and therapeutic techn...
关键词:Gastrointestinal bleeding Vascular anomalies Angioectasia PHARMACOLOGICAL SIROLIMUS 
Inetetamab combined with sirolimus and chemotherapy for the treatment of HER2‐positive metastatic breast cancer patients with abnormal activation of the PI3K/Akt/mTOR pathway after trastuzumab treatment
《Cancer Innovation》2024年第5期102-111,共10页Qiao Li Dan Lv Xiaoying Sun Mengyuan Wang Li Cai Feng Liu Chenghui Li Jiuda Zhao Jing Sun Yehui Shi Fei Ma 
CAMS Innovation Fund for Medical Sciences,Grant/Award Numbers:2021‐I2M‐1‐014,2022‐I2M‐2‐002。
Background:We explored the efficacy and safety of inetetamab combined with sirolimus and chemotherapy for the treatment of human epidermal factor receptor 2(HER2)‐positive metastatic breast cancer patients with abnor...
关键词:CHEMOTHERAPY inetetamab metastatic HER2‐positive breast cancer PAM pathway pyrotinib SIROLIMUS 
Long-term efficacy,safety and biocompatibility of a novel sirolimus eluting iron bioresorbable scaffold in a porcine model
《Bioactive Materials》2024年第9期135-146,共12页Ya-Nan Gao Hong-Tao Yang Zi-Feng Qiu Feng Qi Qian-Hong Lu Jian-Feng Zheng Zi-Wei Xi Xin Wang Li Li Gui Zhang De-Yuan Zhang Yu-Die Lu Hai-Ping Qi Hong Qiu Run-Lin Gao Yu-Feng Zheng 
supported by National Key R&D Program of China(grant number 2018YFC1106600);Shenzhen Industrial and Information Technology Bureau(20180309174916657);Science,Technology and Innovation Commission of Shenzhen Municipality(grant number GJHZ20180418190517302);Natural Science Foundation of China(grant number 52101282).
Iron is considered as an attractive alternative material for bioresorbable scaffolds(BRS).The sirolimus eluting iron bioresorbable scaffold(IBS),developed by Biotyx Medical(Shenzhen,China),is the only iron-based BRS w...
关键词:Bioresorbable scaffold Sirolimus eluting iron bioresorbable scaffold Preclinical study Completely bioresorbable Late lumen enlargement 
An E2F7/TSC1-based model for predicting the efficacy of sirolimus after liver transplantation for hepatocellular carcinoma beyond the Milan criteria被引量:1
《Chinese Medical Journal》2024年第16期1973-1975,共3页Lincheng Zhang Wei Zhou Shusen Zheng Sunbin Ling Xiao Xu 
supported by grants from the National Natural Science Foundation of China(Nos.92159202,82273270,and 32171368);National Science and Technology Major Project of China(No.2017ZX10203205).
As a radical treatment for hepatocellular carcinoma(HCC),liver transplantation(LT)has become an ideal treatment option for certain HCC patients.For patients beyond the Milan criteria,high HCC recurrence risk is a vita...
关键词:HEPATOCELLULAR BEYOND predicting 
Sirolimus can promote the disappearance of renal angiomyolipoma associated with tuberous sclerosis complex:a prospective cohort study
《World Journal of Pediatrics》2024年第6期602-610,共9页Shuo Dun Yang-Yang Wang Lin Wan Qiu-Hong Wang Qian Lu Xiao-Yan Yang Qi Zhang Hui-Min Chen Lu-Peng Qiu Li-Ping Zou 
funded by the Capital's Funds for Health Improvement and Research(No.2022-1-5081);National Key Research and Development Program of China(No.2016YFC1000707).
Background Renal angiomyolipoma(RAML)is the most common kidney lesion in patients with tuberous sclerosis complex(TSC),affecting about 80%of patients.It is a benign tumor that grows over time,usually bilaterally,and c...
关键词:ANGIOMYOLIPOMA mTOR inhibitor SIROLIMUS Tuberous sclerosis 
Correlations between serum kidney injury molecule-1,cystatin C and immunosuppressants:A cross-sectional study of renal transplant patients in Bahrain
《Journal of Biomedical Research》2024年第3期269-277,共9页Kannan Sridharan Shamik Shah Mona Al Hammad Fatima Ali Mohammed Sindhan Veeramuthu Mona Abdulla Taher Mustafa Mohamed Hammad Lamees Jawad Eman Farid 
Part of the consumables used in the present study was obtained as a part of funding of a research study from College of Medicine and Medical Sciences,Arabian Gulf University(Grant No.G05/AGU-11/19).
Renal transplant patients receive several immunosuppressive drug regimens that are potentially nephrotoxic for treatment.Serum creatinine is the standard for monitoring kidney function;however,cystatin C(Cys C)and kid...
关键词:KIM-1 cystatin C mycophenolate mofetil TACROLIMUS EVEROLIMUS SIROLIMUS CYCLOSPORINE 
Tuberous sclerosis complex combined with primary lymphedema:A case report被引量:1
《World Journal of Clinical Cases》2024年第15期2642-2648,共7页Xing-Peng Li Xiao-Li Sun Xin Liu Zhe Wen Li-Hua Jiang Yan Fu Yun-Long Yue Ren-Gui Wang 
Supported by National Natural Science Foundation of China,No.61876216.
BACKGROUND Tuberous sclerosis complex(TSC)and primary lymphedema(PLE)are both rare diseases,and it is even rarer for both to occur in the same patient.In this work,we have provided a detailed description of a patient'...
关键词:Tuberous sclerosis complex LYMPHEDEMA SIROLIMUS Multimodal imaging examination Case report 
Clinical analysis of sirolimus as an alternative GVHD prophylaxis for patients with kidney injury undergoing allo-HSCT
《China Medical Abstracts(Internal Medicine)》2024年第1期55-56,共2页孙葳 
Objective To explore the feasibility of sirolimus as an alternative graft versus host disease (GVHD)prophylaxis in patients with kidney injury after allogeneic hematopoietic stem cell transplantation (allo-HSCT).Metho...
关键词:PATIENTS KIDNEY GVHD 
Dermoscopic Assessment of Lymphangioma Circumscriptum Treated With Topical Sirolimus Ointment:A Case Report被引量:1
《International Journal of Dermatology and Venereology》2023年第4期236-238,共3页Balachandra Suryakant Ankad Sankappanavara Veeranna Smitha Sushila Nagur 
Introduction:Lymphangioma circumscriptum (LC) is characterized by malformation of superficial lymphatics.Dermoscopy reveals brownish-yellow lacunae and white septa.In scrotal LC,gray and red areas are also noted.Treat...
关键词:DERMOSCOPY lymphangioma circumscriptum SIROLIMUS 
Rapid response with good toleration of sirolimus for life-threatening neonatal lymphatic malformations
《Pediatric Investigation》2023年第3期206-211,共6页Shixiao Dong Li Li Jiaosheng Xu Zhonglong Han Xia Zheng 
Introduction:Lymphatic malformations(LMs)are rare vascular anomalies predominantly affecting infants,which can be debilitating or life-threatening when complicated with intralesional bleeding or infection.Effective an...
关键词:DOSAGE Lymphatic malformations NEONATES SIROLIMUS 
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