BACKGROUND Kidney transplantation is one of the most effective treatments for patients with end-stage renal disease.However,many regions face low deceased donor rates and limited ABO-compatible transplant availability...
Branchio-oto-renal(BOR)syndrome is an uncommon disorder inherited in an autosomal dominant manner.Its main clinical manifestations include branchial cleft cysts,anterior auricular fistula,hearing impairment,and kidney...
BACKGROUND Childhood obesity is a significant public health concern,particularly amongst children with chronic kidney disease requiring kidney transplant(KT).Obesity,defined as a body mass index(BMI)of 30 kg/m²or grea...
BACKGROUND Proliferative lupus nephritis(PLN)is the most severe form of lupus nephritis(LN).There are limited data available on renal outcomes of PLN from developing countries.AIM To determine the clinicopathological ...
BACKGROUND Kidney is the vital organ that plays a great role in maintaining an optimal internal environment.The normal kidney function can be altered by physical injury or disease.Currently,chronic kidney disease(CKD)...
supported by the National Key R&D Program of China(2022YFC2502500 and 2022YFC2502502);the National Natural Science Foundation of China(82130021 and 82200752);the Capital’s Funds for Health Improvement and Research(CFH2022-1-4071);the Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences(2019-I2M-5-046);the Michigan Medicine-Peking University Health Science Center Joint Institute for Translational and Clinical Research(BMU2022JI002).
The kidney’s complex structure and functions are essential for homeostasis.Each human kidney contains one million nephrons surrounded by a vast network of peritubular capillaries that support oxygen and nutrients,and...
Supported by National Natural Science Foundation of China,No.82471616,No.82170418,and No.82271618;Natural Science Foundation of Hubei Province,No.2022CFA015;Central Guiding Local Science and Technology Development Project,No.2022BGE237;Key Research and Development Program of Hubei Province,No.2022BCE001,and No.2023BCB139;Hubei Provincial Health Commission Project,No.WJ2023M151。
We are deeply interested in the recent findings onβ-arrestin 2.Liu et al demonstrated thatβ-arrestin 2 knockout provides significant protection in diabetic nephropathy,underscoring its potential as a promising thera...
Khan et al’single-centre,retrospective study on the use of right or left kidneys in living-donor renal transplantation,offers the opportunity to further discuss a complex and debated topic in clinical transplantation...
BACKGROUND Kidney and liver transplantation are two sub-specialized medical disciplines,with transplant professionals spending decades in training.While artificial intelligencebased(AI-based)tools could potentially as...