EVEROLIMUS

作品数:69被引量:167H指数:6
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相关领域:医药卫生更多>>
相关作者:程卯生王博孙铁民张梦莎张艳华更多>>
相关机构:沈阳药科大学北京大学肿瘤医院上海交通大学北京大学更多>>
相关期刊:《Cellular & Molecular Immunology》《Science China(Life Sciences)》《Acta Pharmacologica Sinica》《World Journal of Gastroenterology》更多>>
相关基金:国家自然科学基金国家高技术研究发展计划北京市自然科学基金更多>>
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Massive simultaneous hepatic and renal perivascular epithelioid cell tumor benefitted from surgery and everolimus treatment:A case report
《World Journal of Gastrointestinal Surgery》2024年第10期3334-3342,共9页Han-Teng Yang Fu-Rong Wang Na He Yuan-Hua She Yong-Yue Du Wen-Gui Shi Jing Yang Gang Chen Shu-Ze Zhang Feng Cui Bo Long Ze-Yuan Yu Jun-Min Zhu Geng-Yuan Zhang 
Supported by Cuiying Scientific and Technological Innovation Program of Lanzhou University Second Hospital,No.CY2022-QN-A13 and No.CY2023-QN-A02;Lanzhou Science and Technology Plan Project,No.2023-4-26;Gansu Provincial Natural Science Foundation Project,No.23JRRA1630 and No.24JRRA331;Gansu Provincial Health Research Program Project,No.GSWSKY-2019-32.
BACKGROUND Perivascular epithelioid cell tumor(PEComa)is a rare mesenchymal neoplasm that predominantly affects the kidney and uterus.The occurrence of this tumor in the liver,particularly with simultaneous involvemen...
关键词:Perivascular epithelioid cell tumor HEPATIC RENAL SURGERY Case report 
Correlations between serum kidney injury molecule-1,cystatin C and immunosuppressants:A cross-sectional study of renal transplant patients in Bahrain
《Journal of Biomedical Research》2024年第3期269-277,共9页Kannan Sridharan Shamik Shah Mona Al Hammad Fatima Ali Mohammed Sindhan Veeramuthu Mona Abdulla Taher Mustafa Mohamed Hammad Lamees Jawad Eman Farid 
Part of the consumables used in the present study was obtained as a part of funding of a research study from College of Medicine and Medical Sciences,Arabian Gulf University(Grant No.G05/AGU-11/19).
Renal transplant patients receive several immunosuppressive drug regimens that are potentially nephrotoxic for treatment.Serum creatinine is the standard for monitoring kidney function;however,cystatin C(Cys C)and kid...
关键词:KIM-1 cystatin C mycophenolate mofetil TACROLIMUS EVEROLIMUS SIROLIMUS CYCLOSPORINE 
Advancements in medical treatment for pancreatic neuroendocrine tumors:A beacon of hope被引量:1
《World Journal of Gastroenterology》2024年第12期1670-1675,共6页Somdatta Giri Jayaprakash Sahoo 
This editorial highlights the remarkable advancements in medical treatment strategies for pancreatic neuroendocrine tumors(pan-NETs),emphasizing tailored approaches for specific subtypes.Cytoreductive surgery and soma...
关键词:Pancreatic neuroendocrine tumor Medical management Somatostatin analog IMMUNOTHERAPY EVEROLIMUS 
Influence of immunosuppressive drugs on natural killer cells in therapeutic drug exposure in liver transplantation
《Hepatobiliary Surgery and Nutrition》2023年第6期835-853,I0002-I0005,共23页Rongrong Qin Jiwei Qin Xuefeng Li Zhijun Xu Peiqi He Xiaodong Yuan Cheng Sun Björn Nashan 
funded by Björn Nashan Research Start-up Fund (2018KYQ003RC2017001);National Natural Science Foundation of China (#8202290021,#92169118,#91942310);National Key Research and Development Program of China (#2021YFC2300600);Anhui Provincial Natural Science Foundation (#2008085J35);the Fundamental Research Funds for the Central Universities (WK9110000055).
Background:Natural killer(NK)cells are enriched in the liver and are the main regulators in liver transplantation regarding rejection or tolerance,viral infection,or tumor recurrence.Immunosuppression consists of a tr...
关键词:Liver transplantation NK cells IMMUNOSUPPRESSANTS calcineurin inhibitor(CNI) EVEROLIMUS 
Pneumocystis jirovecii diagnosed by next-generation sequencing of bronchoscopic alveolar lavage fluid: A case report and review of literature
《World Journal of Clinical Cases》2023年第4期866-873,共8页Qing-Wei Cheng Hong-Li Shen Zhi-Hui Dong Qian-Qian Zhang Ya-Fen Wang Jin Yan Yu-Sheng Wang Ning-Gang Zhang 
BACKGROUND The advent of molecular targeted agents and immune checkpoint inhibitors has greatly improved the treatment of advanced renal cell carcinoma(RCC), thus significantly improving patient survival. The incidenc...
关键词:Renal cell carcinoma EVEROLIMUS Pneumocystis jirovecii pneumonia Next-generation sequencing Bronchoscopic alveolar lavage fluid Case report 
Piceatannol enhances Beclin-1 activity to suppress tumor progression and its combination therapy strategy with everolimus in gastric cancer被引量:2
《Science China(Life Sciences)》2023年第2期298-312,共15页Longtao Huangfu Xiaoyang Wang Shanshan Tian Junbing Chen Xueying Wang Biao Fan Qian Yao Gangjian Wang Cong Chen Jing Han Xiaofang Xing Jiafu Ji 
supported by the Natural Science Foundation of Beijing,China(7214215);the Beijing Municipal Administration of Hospitals Incubating Program(PZ2021025);the Science Foundation of Peking University Six Hospital(YJJ0008);the National Natural Science Foundation of China(82203579,81872502,81402308);the Science Foundation of Peking University Cancer Hospital(2020-23,2021-24,202126);the Clinical Medicine Plus X-Young Scholars Project(PKU2020LCXQ001);the“Double First Class”Disciplinary Development Foundation of Peking University(BMU2019LCKXJ011);The first author,Longtao Huangfu,would like to give special thanks to the Beijing Natural Science Foundation Committee for granting the first research grant。
The effects and regulation of Beclin-1-an autophagy-related protein-have not been fully defined, however, a negative correlation has been reported between Beclin-1 expression and carcinogenesis. Meanwhile, no compound...
关键词:PICEATANNOL BECLIN-1 autophagy EVEROLIMUS gastric cancer drug synergy 
Bone marrow metastatic neuroendocrine carcinoma with unknown primary site:A case report and review of the literature
《World Journal of Clinical Cases》2022年第30期11074-11081,共8页Xue-Bing Shi Wen-Xia Deng Feng-Xiang Jin 
BACKGROUND Metastatic neuroendocrine carcinoma(NEC) of bone marrow is uncommon.Here,we report a case of bone marrow metastatic NEC with an unknown primary site.CASE SUMMARY A 73-year-old Chinese woman was admitted to ...
关键词:Neuroendocrine neoplasm Bone marrow metastasis Bone marrow necrosis MYELOFIBROSIS EVEROLIMUS Case report 
Current role of surgery for tuberous sclerosis complex-associated epilepsy被引量:3
《Pediatric Investigation》2022年第1期16-22,共7页Nicola Specchio Giusy Carfi Pavia Luca de Palma Alessandro De Benedictis Chiara Pepi Marta Conti Carlo Efisio Marras Federico Vigevano Paolo Curatolo 
Tuberous sclerosis complex(TSC)is a rare multisystem,autosomal dominant neurocutaneous syndrome in which epilepsy is the most common of several neurological and psychiatric manifestations.Around two thirds of patients...
关键词:EPILEPSY EVEROLIMUS Imaging PROGNOSTICS SURGERY Tuberous sclerosis complex(TSC) 
c-MYC-mediated TRIB3/P62^(+) aggresomes accumulation triggers paraptosis upon the combination of everolimus and ginsenoside Rh2被引量:3
《Acta Pharmaceutica Sinica B》2022年第3期1240-1253,共14页Min-Xia Su Yu-Lian Xu Xiao-Ming Jiang Mu-Yang Huang Le-Le Zhang Luo-Wei Yuan Xiao-Huang Xu Qi Zhu Jian-Li Gao Jia-Hong Lu Xiuping Chen Ming-Qing Huang Yitao Wang Jin-Jian Lu 
supported by the National Natural Science Foundation of China(No.81973516);partially supported by the Science and Technology Development Fund,Macao S.A.R,China(Nos.024/2016/A1 and 0129/2019/A3);University of Macao(No.CPG2021-00022-ICMS)。
The mammalian target of rapamycin(m TOR) pathway is abnormally activated in lung cancer.However, the anti-lung cancer effect of m TOR inhibitors as monotherapy is modest. Here, we identified that ginsenoside Rh2, an a...
关键词:EVEROLIMUS Ginsenoside Rh2 Paraptosis AGGRESOMES P62 TRIB3 C-MYC Lung cancer 
Diagnosis and guidance of treatment of breast cancer cutaneous metastases by multiple needle biopsy: A case report
《World Journal of Clinical Cases》2022年第1期345-352,共8页Zhong-Hui Li Fang Wang Ping Zhang Peng Xue Shi-Jie Zhu 
BACKGROUND Breast cancer patients have a high skin metastasis rate.However,reports on treatment of cutaneous metastases of breast cancer are scarce.CASE SUMMARY We report the treatment process for one breast cancer ca...
关键词:Breast cancer Cutaneous metastases Needle biopsy Exemestane and everolimus Case report 
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