Supported by Cuiying Scientific and Technological Innovation Program of Lanzhou University Second Hospital,No.CY2022-QN-A13 and No.CY2023-QN-A02;Lanzhou Science and Technology Plan Project,No.2023-4-26;Gansu Provincial Natural Science Foundation Project,No.23JRRA1630 and No.24JRRA331;Gansu Provincial Health Research Program Project,No.GSWSKY-2019-32.
BACKGROUND Perivascular epithelioid cell tumor(PEComa)is a rare mesenchymal neoplasm that predominantly affects the kidney and uterus.The occurrence of this tumor in the liver,particularly with simultaneous involvemen...
Part of the consumables used in the present study was obtained as a part of funding of a research study from College of Medicine and Medical Sciences,Arabian Gulf University(Grant No.G05/AGU-11/19).
Renal transplant patients receive several immunosuppressive drug regimens that are potentially nephrotoxic for treatment.Serum creatinine is the standard for monitoring kidney function;however,cystatin C(Cys C)and kid...
This editorial highlights the remarkable advancements in medical treatment strategies for pancreatic neuroendocrine tumors(pan-NETs),emphasizing tailored approaches for specific subtypes.Cytoreductive surgery and soma...
funded by Björn Nashan Research Start-up Fund (2018KYQ003RC2017001);National Natural Science Foundation of China (#8202290021,#92169118,#91942310);National Key Research and Development Program of China (#2021YFC2300600);Anhui Provincial Natural Science Foundation (#2008085J35);the Fundamental Research Funds for the Central Universities (WK9110000055).
Background:Natural killer(NK)cells are enriched in the liver and are the main regulators in liver transplantation regarding rejection or tolerance,viral infection,or tumor recurrence.Immunosuppression consists of a tr...
BACKGROUND The advent of molecular targeted agents and immune checkpoint inhibitors has greatly improved the treatment of advanced renal cell carcinoma(RCC), thus significantly improving patient survival. The incidenc...
supported by the Natural Science Foundation of Beijing,China(7214215);the Beijing Municipal Administration of Hospitals Incubating Program(PZ2021025);the Science Foundation of Peking University Six Hospital(YJJ0008);the National Natural Science Foundation of China(82203579,81872502,81402308);the Science Foundation of Peking University Cancer Hospital(2020-23,2021-24,202126);the Clinical Medicine Plus X-Young Scholars Project(PKU2020LCXQ001);the“Double First Class”Disciplinary Development Foundation of Peking University(BMU2019LCKXJ011);The first author,Longtao Huangfu,would like to give special thanks to the Beijing Natural Science Foundation Committee for granting the first research grant。
The effects and regulation of Beclin-1-an autophagy-related protein-have not been fully defined, however, a negative correlation has been reported between Beclin-1 expression and carcinogenesis. Meanwhile, no compound...
BACKGROUND Metastatic neuroendocrine carcinoma(NEC) of bone marrow is uncommon.Here,we report a case of bone marrow metastatic NEC with an unknown primary site.CASE SUMMARY A 73-year-old Chinese woman was admitted to ...
Tuberous sclerosis complex(TSC)is a rare multisystem,autosomal dominant neurocutaneous syndrome in which epilepsy is the most common of several neurological and psychiatric manifestations.Around two thirds of patients...
supported by the National Natural Science Foundation of China(No.81973516);partially supported by the Science and Technology Development Fund,Macao S.A.R,China(Nos.024/2016/A1 and 0129/2019/A3);University of Macao(No.CPG2021-00022-ICMS)。
The mammalian target of rapamycin(m TOR) pathway is abnormally activated in lung cancer.However, the anti-lung cancer effect of m TOR inhibitors as monotherapy is modest. Here, we identified that ginsenoside Rh2, an a...
BACKGROUND Breast cancer patients have a high skin metastasis rate.However,reports on treatment of cutaneous metastases of breast cancer are scarce.CASE SUMMARY We report the treatment process for one breast cancer ca...