Advancements in medical treatment for pancreatic neuroendocrine tumors:A beacon of hope  

作　　者：Somdatta Giri Jayaprakash Sahoo 

机构地区：[1]Department of Endocrinology and Metabolism,Jawaharlal Institute of Postgraduate Medical Education and Research,Puducherry,605006,India

出　　处：《World Journal of Gastroenterology》2024年第12期1670-1675,共6页世界胃肠病学杂志（英文版）

摘　　要：This editorial highlights the remarkable advancements in medical treatment strategies for pancreatic neuroendocrine tumors(pan-NETs),emphasizing tailored approaches for specific subtypes.Cytoreductive surgery and somatostatin analogs(SSAs)play pivotal roles in managing tumors,while palliative options such as molecular targeted therapy,peptide receptor radionuclide therapy,and chemotherapy are reserved for SSA-refractory patients.Gastrinomas,insul-inomas,glucagonomas,carcinoid tumors and VIPomas necessitate distinct thera-peutic strategies.Understanding the genetic basis of pan-NETs and exploring immunotherapies could lead to promising avenues for future research.This review underscores the evolving landscape of pan-NET treatment,offering renewed hope and improved outcomes for patients facing this complex disease.

关 键 词：Pancreatic neuroendocrine tumor Medical management Somatostatin analog IMMUNOTHERAPY EVEROLIMUS 

分 类 号：R735.9[医药卫生—肿瘤]