PICEATANNOL

作品数:6被引量:8H指数:2
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相关作者:刘丹更多>>
相关机构:沈阳药科大学更多>>
相关期刊:《Science China(Life Sciences)》《中华糖尿病杂志》《中国医药导报》《Acta Biochimica et Biophysica Sinica》更多>>
相关基金:国家自然科学基金北京市自然科学基金国家教育部博士点基金更多>>
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Piceatannol enhances Beclin-1 activity to suppress tumor progression and its combination therapy strategy with everolimus in gastric cancer被引量:2
《Science China(Life Sciences)》2023年第2期298-312,共15页Longtao Huangfu Xiaoyang Wang Shanshan Tian Junbing Chen Xueying Wang Biao Fan Qian Yao Gangjian Wang Cong Chen Jing Han Xiaofang Xing Jiafu Ji 
supported by the Natural Science Foundation of Beijing,China(7214215);the Beijing Municipal Administration of Hospitals Incubating Program(PZ2021025);the Science Foundation of Peking University Six Hospital(YJJ0008);the National Natural Science Foundation of China(82203579,81872502,81402308);the Science Foundation of Peking University Cancer Hospital(2020-23,2021-24,202126);the Clinical Medicine Plus X-Young Scholars Project(PKU2020LCXQ001);the“Double First Class”Disciplinary Development Foundation of Peking University(BMU2019LCKXJ011);The first author,Longtao Huangfu,would like to give special thanks to the Beijing Natural Science Foundation Committee for granting the first research grant。
The effects and regulation of Beclin-1-an autophagy-related protein-have not been fully defined, however, a negative correlation has been reported between Beclin-1 expression and carcinogenesis. Meanwhile, no compound...
关键词:PICEATANNOL BECLIN-1 autophagy EVEROLIMUS gastric cancer drug synergy 
Piceatannol attenuates streptozotocin-induced type 1 diabetes inmice
《BIOCELL》2020年第3期353-361,共9页MENGSHU ZHAO PINGSHI GAO LIANG TAO JINGJING WEN LEI WANG YUGUO YI YUXIN CHEN JUNSONG WANG XI XU JIANFA ZHANG DAN WENG 
the National Natural Science Foundation of China under Grant 21677076 and 31970897 to DW;Outstanding Youth Foundation of Jiangsu Province(BK20190093)to DW;Qing Lan Project of Jiangsu Province to DW,the Fundamental Research Funds for the Central Universities No.30919011102 to DW,the Innovative and Entrepreneurial Talent Cultivation(Shuangchuang)Program of Jiangsu Province to DW.
As a natural analog of resveratrol,piceatannol(Pic)exhibits good antioxidant and anti-inflammatory activities in different disease models.However,the role of Pic in type 1 diabetes mousemodel has not been reported yet...
关键词:PICEATANNOL Type 1 DIABETES STREPTOZOTOCIN OXIDATIVE STRESS Inflammation ER STRESS 
PP2 and piceatannol inhibit PrP106-126-induced iNOS activation mediated by CD36 in BV2 microglia被引量:2
《Acta Biochimica et Biophysica Sinica》2013年第9期763-772,共10页Siming Zhang Lifeng Yang Mohammed Kouadir Rongrong Tan Yun Lu Jiaxin Chang Binrui Xu Xiaomin Yin Xiangmei Zhou Deming Zhao 
This work was supported by grants from the National Natural Science Foundation of China (No. 31001048, No. 31172293, and No. 31272532), the Specialized Research Fund for the Doctoral Program of Higher Education (No. 20100008120002), the Foundation of Chinese Ministry of Science and Technology (Proj ect No. 2011BAI 15B01), and the Program for Cheung Kong Scholars and Innovative Research Team in University of China (No. IRT0866).
Prion diseases are a group of transmissible fatal neurodegen- erative disorders of humans and animals, including bovine spongiform encephalopathy, scrapie, and Creutzfeldt- Jakob disease. Microglia, the resident macro...
关键词:CD36 pp2 piceatannol (Pic) PrP106-126 bv2microglia INOS 
piceatannol在分化早期通过调节分裂增殖及胰岛素受体依赖性信号通路抑制脂肪生成
《中华糖尿病杂志》2012年第5期320-320,共1页贾黎静(译校) 
piceatannol是一种天然的均二苯乙烯,与白藜芦醇结构类似。虽然曾有人利用白藜芦醇治疗肥胖,但是piceatannol在脂肪组织形成及相关疾病中的作用机制仍不清楚。
关键词:脂肪生成 受体依赖性 信号通路 胰岛素 增殖 分裂 调节 早期 
藏边大黄中茋类化合物Piceatannol的含量测定
《中国医药导报》2009年第4期40-41,共2页刘兵 谢韵琪 
目的:建立藏边大黄中茋类化合物Piceatannol的含量测定方法。方法:采用HPLC法,色谱柱为Kromasil ODS色谱柱(150mm×4.6mm,5μm);流动相为乙腈-水(25∶75,V/V);流速为1.0ml/min;检测波长为325nm;柱温为30℃。结果:Piceatannol在0.0591~0...
关键词:藏边大黄 HPLC 茋类化合物 PICEATANNOL 
Studies on the Synthesis of a Natural Product-Piceatannol and its Analogs被引量:4
《Chinese Chemical Letters》2002年第6期521-524,共4页Zhi Song PIAO Lin WANG Ya Bin FENG Zhi Zhong ZHAO 
Piceatannol, (E)-3, 3, 4, 5-tetrahydroxy stilbene, a natural polyhydroxy stilbene, possesses many biological activities, its synthesis has been reported. We designed another route of its synthesis, which can be contr...
关键词:Total synthesis PICEATANNOL analogs. 
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