supported by the Natural Science Foundation of Beijing,China(7214215);the Beijing Municipal Administration of Hospitals Incubating Program(PZ2021025);the Science Foundation of Peking University Six Hospital(YJJ0008);the National Natural Science Foundation of China(82203579,81872502,81402308);the Science Foundation of Peking University Cancer Hospital(2020-23,2021-24,202126);the Clinical Medicine Plus X-Young Scholars Project(PKU2020LCXQ001);the“Double First Class”Disciplinary Development Foundation of Peking University(BMU2019LCKXJ011);The first author,Longtao Huangfu,would like to give special thanks to the Beijing Natural Science Foundation Committee for granting the first research grant。
The effects and regulation of Beclin-1-an autophagy-related protein-have not been fully defined, however, a negative correlation has been reported between Beclin-1 expression and carcinogenesis. Meanwhile, no compound...
the National Natural Science Foundation of China under Grant 21677076 and 31970897 to DW;Outstanding Youth Foundation of Jiangsu Province(BK20190093)to DW;Qing Lan Project of Jiangsu Province to DW,the Fundamental Research Funds for the Central Universities No.30919011102 to DW,the Innovative and Entrepreneurial Talent Cultivation(Shuangchuang)Program of Jiangsu Province to DW.
As a natural analog of resveratrol,piceatannol(Pic)exhibits good antioxidant and anti-inflammatory activities in different disease models.However,the role of Pic in type 1 diabetes mousemodel has not been reported yet...
This work was supported by grants from the National Natural Science Foundation of China (No. 31001048, No. 31172293, and No. 31272532), the Specialized Research Fund for the Doctoral Program of Higher Education (No. 20100008120002), the Foundation of Chinese Ministry of Science and Technology (Proj ect No. 2011BAI 15B01), and the Program for Cheung Kong Scholars and Innovative Research Team in University of China (No. IRT0866).
Prion diseases are a group of transmissible fatal neurodegen- erative disorders of humans and animals, including bovine spongiform encephalopathy, scrapie, and Creutzfeldt- Jakob disease. Microglia, the resident macro...
Piceatannol, (E)-3, 3, 4, 5-tetrahydroxy stilbene, a natural polyhydroxy stilbene, possesses many biological activities, its synthesis has been reported. We designed another route of its synthesis, which can be contr...