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Preparation, characterization and evaluation of kaempferol phospholipid complex: Improvement of its solubility and biological effect: 《Journal of Polyphenols》2024年第2期56-64,共9页Dezhi Gao Honghui Zhao Fengmao Zou Ming Yang Jing Wang Lina Fang Xu Zhao; funded by Young and Middle Aged Teachers’Career Development Support Project of Shenyang Pharmaceutical University(ZQN2019005).; Kaempferol(KA),as one of the flavonoids,has extensive pharmacological properties.However,the poor solubility of KA severely limits its clinical application.In our study,the kaempferol phospholipid complex(KA-PC)has be...; 关键词：KAEMPFEROL phospholipid complex SOLUBILITY uric acid-lowering effect

Effects of ginkgo flavone aglycone on atherosclerosis based on network pharmacology,molecular docking,and in vitro experiments被引量：1: 《TMR Modern Herbal Medicine》2024年第2期1-10,共10页Miao Zhou Rui Li Qin Li Yan-Li Huang Shi-Jing Liu Ji-Yu Chen Yan He; supported by the Science and Technology Foundation of Basic Research Program of Guizhou Province([2023]General 371,[2020]1Y381);the Administration of Traditional Chinese Medicine of Guizhou Province(QZYY-2018-130);the project of Key Laboratory of Basic Pharmacology of Ministry of Education,Zunyi Medicial University(No.qianjiaoheKYzi[2022]395);the Cultivation Plan of the NSFC(National Natural Science Foundation of China)of the affiliated hospital of Guizhou Medical University(GYFYNSFC-2021-55,GYFYNSFC-2021-56);the Cultivation Plan of the NSFC(National Natural Science Foundation of China)of Guizhou Medical University(21NSFCP13);the Science and Technology Foundation of Health Commission of Guizhou Province(gzwkj 2022-221).; Background:Ginkgo flavone aglycones(GA),a Ginkgo(Ginkgo biloba)extract,has been proven to have good biological activity in atherosclerosis(AS)treatment.Moreover,its active compounds and the corresponding mechanism for...; 关键词：network pharmacology ginkgo flavone aglycones ATHEROSCLEROSIS molecular docking KAEMPFEROL QUERCETIN ISORHAMNETIN

Kaempferol ameliorated levodopa-induced dyskinesia in experimental rats: A role of brain monoamines, cFOS, FosB, Parkin, Pdyn, TH, and p-JNK: 《BIOCELL》2024年第3期513-523,共11页PEI QIN MIAO LIU XIN WANG JIANHUA MA; Background:L-dopa(Levodopa)is well known for managing PD(Parkinson’s disease);however,its prolonged use caused dyskinesia(LID).Due to the varied presentation of LID,effective treatment options are scarce.Flavonoids r...; 关键词：AIMS CFOS KAEMPFEROL Levodopa-induced dyskinesia Pdyn

Targeting colorectal cancer using dietary flavonols: 《Cancer Innovation》2024年第1期124-132,共9页Nitin Dubey Nidhi Dubey Upendra Bhadoria Kamal Shah Nagendra Singh Chauhan; Colorectal cancer is among the well-known forms of cancer and a prominent cause of cancer demises worldwide.In vitro experiments reinforced by animal studies,as well as epidemiological studies of human colorectal canc...; 关键词：ISORHAMNETIN KAEMPFEROL MYRICETIN QUERCETIN

Kaempferol improves glucose uptake in skeletal muscle via an AMPK-dependent mechanism: 《Food Science and Human Wellness》2023年第6期2087-2094,共8页William T.Moore Jing Luo Dongmin Liu; partially supported by grants from Diabetes Action Research and Education Foundation。; Insulin resistance is a hallmark of type-2 diabetes(T2D)pathogenesis.Because skeletal muscle(SkM)is the major tissue for insulin-mediated glucose disposal,insulin resistance in SkM is considered a major risk factor fo...; 关键词：KAEMPFEROL Skeletal muscle AMPK AKT Insulin resistance

Kaempferol and its derivatives:Biological activities and therapeutic potential: 《Asian Pacific Journal of Tropical Biomedicine》2023年第10期411-420,共10页Shazia Parveen Irshad Ul Haq Bhat Rajeev Bhat; Kaempferol,a natural plant-origin flavonoid,exhibits therapeutic anti-inflammatory,antioxidant,anticancer,antidiabetic,and neuroprotective properties.Kaempferol acts within several distinct mechanisms like apoptotic i...; 关键词：KAEMPFEROL Therapeutic effects BIOACTIVITIES Fruits and vegetable wastes Sustainable alternative sources

Comparison of Apigenin,Quercetin and Kaempferol Accumulation and Total Flavonoid Content in Leaves,Embryogenic Cultures and Cell Suspension Cultures of Parsley(Petroselinum crispum): 《Phyton-International Journal of Experimental Botany》2023年第10期2807-2823,共17页Laura Isabel Arias-Rodríguez Martha Alicia Rodríguez-Mendiola Carlos Arias-Castro Federico Antonio Gutiérrez Miceli Diana Reséndez Pérez María Celina Luján Hidalgo Juan JoséVillalobos Maldonado Norma Alejandra Mancilla Margalli; supported by financial assistance from Smart Biotechnology S.A.de C.V.We gratefully acknowledge their contribution and support in the form of funding for this research project.; In recent years,there has been a growing interest in exploring alternative treatments for bone defects.Bone tissue engineering has turned its attention to plant extracts containing osteogenic flavonoids as potential p...; 关键词：Parsley(Petroselinum crispum)cultures osteogenic flavonoids bone regeneration aqueous extracts

Discovery of Kaempferol,a Novel ADAM10 Inhibitor,as a Potential Treatment for Staphylococcus aureus Infection: 《Engineering》2023年第9期206-221,共16页Tingting Wang Jianfeng Wang Xiangzhu Xu Fan Jiang Hongfa Lv Qinghui Qi Can Zhang Qianghua Lv Xuming Deng; supported by the National Natural Science Foundation of China(U22A20523,32172912,and 32102722);the Interdisciplinary Integration and Innovation Project of Jilin University(JLUXKJC2021QZ04)。; Host-directed therapy(HDT)is an emerging novel approach for treating multidrug-resistant Staphylococcus aureus(S.aureus)infection.Functioning as the indispensable specific cellular receptor for a-toxin(Hla),a-disinteg...; 关键词：Host-directed therapy KAEMPFEROL ADAM10 inhibitor Staphylococcus aureus infection Barrier disruption NECROPTOSIS

Research progress and quality markers prediction analysis of Dysosma versipellis被引量：1: 《Traditional Medicine Research》2023年第3期36-50,共15页Yuan-Hui Guo Peng Lu Jia-Xing He Bao-Nan Ma Ebuka-Olisaemeka Nwafor Wen-Xin Wang Chuan-Xin Liu; the National Natural Science foundation of China(No.82204938).; Dysosma versipellis is the rhizome of Bajiaolian in Berberaceae.It is a unique medicinal plant in China and it was the first to be recorded in Shennong’s Classic of Materia Medica(unknown author,25–220 C.E.).It has ...; 关键词：Dysosma versipellis lignans FLAVONOIDS chemical composition pharmacological activity toxicological effect quality marker podophyllotoxin KAEMPFEROL QUERCETIN

Junctional adhesion molecule-like protein as a novel target for kaempferol to ameliorate lung adenocarcinoma被引量：2: 《Journal of Integrative Medicine》2023年第3期268-276,共9页Qian Wu Yong-bin Wang Xiao-wen Che Hui Wang Wei Wang; supported by the National Natural Science Foundation of China(Grant No.81973630);National Clinical Key Specialty Project Foundation(Grant No.Z155080000004).; Objective:Although there have been improvements in targeted therapy and immunotherapy,the majority of lung adenocarcinoma(LUAD)patients still lack effective therapies.Consequently,it is urgent to screen for new diagno...; 关键词：Junctional adhesion molecule-like protein KAEMPFEROL Lung adenocarcinoma PROLIFERATION INVASION MIGRATION

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