Research progress and quality markers prediction analysis of Dysosma versipellis  

作　　者：Yuan-Hui Guo Peng Lu Jia-Xing He Bao-Nan Ma Ebuka-Olisaemeka Nwafor Wen-Xin Wang Chuan-Xin Liu 

机构地区：[1]Endocrine and Metabolic Disease Center,First Affiliated Hospital,and College of Clinical Medicine of Henan University of Science and Technology,Medical Key Laboratory of Hereditary Rare Diseases of Henan,Luoyang Sub-center of National Clinical Research Center for Metabolic Diseases,Luoyang 471000,China [2]Department of Pharmacy,Suzhou TCM Hospital Affiliated to Nanjing University of Chinese Medicine,Suzhou 215009,China [3]College of Traditional Chinese Medicine,Beijing University of Traditional Chinese Medicine,Beijing 100029,China [4]School of Health&Biomedical Sciences,RMIT University–Bundoora Campus,Melbourne 3083,Australia [5]School of Biological and Medical Engineering,Beihang Univesity,Beijing 100083,China

出　　处：《Traditional Medicine Research》2023年第3期36-50,共15页TMR传统医学研究

基　　金：the National Natural Science foundation of China(No.82204938).

摘　　要：Dysosma versipellis is the rhizome of Bajiaolian in Berberaceae.It is a unique medicinal plant in China and it was the first to be recorded in Shennong’s Classic of Materia Medica(unknown author,25–220 C.E.).It has complex chemical components as well as complex,pharmacological and toxicological effects are extensive.Based on the recent research progress,the chemical constituents,pharmacological activities and toxicological effects of Dysosma versipellis were summarized.Combined with the core concept of quality markers of traditional Chinese medicine,the prediction and analysis were carried out from the aspects of phytogenetics and the source pathway of specific chemical constituents,traditional medicinal properties,traditional efficacy,chemical composition measurability,blood components,and pharmacokinetics,in order to provide reference for further study of Dysosma versipellis.

关 键 词：Dysosma versipellis lignans FLAVONOIDS chemical composition pharmacological activity toxicological effect quality marker podophyllotoxin KAEMPFEROL QUERCETIN 

分 类 号：R284.1[医药卫生—中药学]