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The Clinical Medicine Special Project of Nantong University for financial support(Grant No.2022JQ011)。
Two total synthetic routes for the preparation of myricetin were designed and explored.It was validated that route B presented an efficient approach to synthesizing myricetin,starting from commercially available and i...
Colorectal cancer is among the well-known forms of cancer and a prominent cause of cancer demises worldwide.In vitro experiments reinforced by animal studies,as well as epidemiological studies of human colorectal canc...
Supported by National Natural Science Foundation of China,No.82205025,No.82374355 and No.82174293;Subject of Jiangsu Province Hospital of Chinese Medicine,No.Y21023;Forth Batch of Construction Program for Inheritance Office of Jiangsu Province Famous TCM Experts,No.[2021]7.
BACKGROUND Development of end-stage renal disease is predominantly attributed to diabetic nephropathy(DN).Previous studies have indicated that myricetin possesses the potential to mitigate the pathological alterations...
Good nutrition plays a crucial role in maintaining a balanced lifestyle. The beneficial effects of nutrition have been found to counteract nutritional disturbances with the expanded use of nutraceuticals to treat and ...
Objective:To evaluate the effect of myricetin on ovalbumin(OVA)-induced allergic rhinitis in mice.Methods:Mice were sensitized and challenged using OVA(5%,500 mL)intraperitoneally and intranasally,respectively,on an a...
supported by Research Project Supported by Shanxi Scholarship Council of China(2020-101);Shandong Natural Science Foundation of Shandong,China(ZR2022MC118).
Type 2 diabetes mellitus(T2DM)and Alzheimer disease(AD)are two independent non-infectious diseases,however,evidences demonstrate that insulin resistance(IR)directly affects the glucose metabolism of the central nervou...
Science and Technology Development Fund,Macao SAR(0129/2019/A3;176/2017/A3);and University of Macao(MYRG2018-00165-ICMS)。
OBJECTIVE Programmed death ligand-1(PD-L1)and indoleamine 2,3-dioxygenase 1(IDO1)are immune checkpoints which can be induced by interferon-γ(IFN-γ)in the tumor microenvironment,leading to immune escape of tumors.Myr...
Vine tea has been used as an herbal tea by several ethnic minorities for hundreds of years in China.Flavonoids,a kind of indispensable component in a variety of nutraceutical,pharmaceutical and cosmetic applications,a...
supported by the National Natural Science Foundation of China,No.81671249;the Natural Science Foundation of Shandong Province of China,No.ZR2016CM04(both to ZGM).
Multiple studies implicate iron accumulation in the substantia nigra in the degeneration of dopaminergic neurons in Parkinson’s disease.Indeed,slowing of iron accumulation in cells has been identified as the key poin...
The aim of this study was to determine the levels of myricetin, quercetin, and kaempferol in green and black Kenyan types in relation to geographic location of production. Tea samples were extracted before chromatogra...