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supported by the Key Research and Development Program of Hunan Province of China(No.2022NK2036);Xiangxi Prefecture Science and Technology Plan Project"School-Local Integration"Special Project(No.2022001);the scientific research project of Hunan Provincial Department of Education(No.22B0520).
Background:Ampelopsis grossedentata,vine tea,which is the tea alternative beverages in China.In vine tea processing,a large amount of broken tea is produced,which has low commercial value.Methods:This study investigat...
The authors disclosed receipt of the following financial support for the research,authorship,and/or publication of this article:This work was supported by Mechanism of Dihydromyricetin Inhibiting Multiple Myeloma Growth and Epithelial Mesenchymal Transition by Regulating STAT1/RIG-I Pathway(Grant Number 2022KY094).
Multiple myeloma(MM)is a plasma cell malignancy and remains incurable as it lacks effective curative approaches;thus,novel therapeutic strategies are desperately needed.The study aimed to explore the therapeutic role ...
International Science and Technology Cooperation Project of China,Grant/Award Number:2022YFE0133300;National Natural Science Foundation of China,Grant/Award Numbers:82172801,81972454。
Background:Programmed death ligand 1(PD-L1)has been demonstrated to facilitate tumor progression and therapeutic resistance in an immuneindependent manner.Nevertheless,the function and underlying signaling network(s)o...
Supported by Science Foundation of Education Department of Shaanxi Provincial Government (No.19JK0890);Natural Science Foundation of Xizang (Tibet) Autonomous Region (No.XZ202001ZR0089G);Major Training Project of Xizang Minzu University (Nos.18MDZ03 and 20MDT03);Funded Project of Young Scholar Cultivation Program of Xizang Minzu University (No.21MDX04)。
Objective: To investigate the effect and potential mechanism of dihydromyricetin(Dmy) on H9C2 cell proliferation, apoptosis, and autophagy. Methods: H9C2 cells were randomly divided into 7 groups, namely control, mode...
supported by the National Natural Science Foundation of China(Grant No.32160610);Incubation Project for High-Level Scientific Research Achievements of Hubei Minzu University(Grant No.4205017).
To explore the dihydromyricetin or eugenol loaded nanofiber’s potential as food active packaging,0%,0.1%,0.5%,and 1.0%dihydromyricetin or eugenol loaded nanofibers were fabricated by electro-blowing spinning,which in...
This work was financially supported by the Fellowship of China National Postdoctoral Program for Innovative Talants(BX20220240);the Improvement Project for Theranostic Ability on Difficulty Miscellaneous Disease(Tumor)from National Health Commission of China(ZLYNXM202006);the Chinese Central Special Fund for Local Science and Technology Development of Hubei Province(2018ZYYD023);the Science and Technology Department of Hubei Province Key Project(2018ACA159).
The harsh microenvironment in wound(HMW)remains a major obstacle to chronic wound healing.Although a series of bioactive materials have been developed,few of them are multi-functional and able to accelerate wound heal...
Natural Science Foundation of Hunan Province(Grant No.2018JJ2347,2021JJ30595);Hunan Provincial Postgrad uate Scientific Research Innovation Project(Grant No.CX20211061);and the Jishou University School-level Scientific Research Project(Grant No.Jdzd21028)。
It has been reported that the histone/protein deacetylase SIRT1-AMP-activated protein kinase(SIRT1-AMPK)signaling pathway may play a role in the effects of dihydromyricetin(DHM)on improving triglyceride(TG)accumulatio...
Vine tea has been used as an herbal tea by several ethnic minorities for hundreds of years in China.Flavonoids,a kind of indispensable component in a variety of nutraceutical,pharmaceutical and cosmetic applications,a...
the National Natural Science Foundation of China(NSFC,Grant No.31801459,31701520);Science and Technology General Projects of Fujian Province(2019J01393);Educational research project for young and middleaged teachers in Fujian Province(JT180116).
Dihydromyricetin(DHM),as a bioactive flavanonol compound,is mainly found in“Tengcha”(Ampelopsis grossedentata)cultivated in south of China.This study aimed to investigate the anti-hyperglycemic and antidyslipidemic ...
Supported by the National Natural Science Foundation of China (Regulation and Mechanism of Bone Marrow Mesenchymal Stem Cells on the Characteristics of Nasopharyngeal Carcinoma Stem Cells, No.81272434);the Medical Research Fund of Guangdong Province (Effect of Berberine on Growth of Transplanted Tumor of Nasopharyngeal Carcinoma in Mice Based on JAK/STAT3 Signaling Pathway, No.A2016431)。
OBJECTIVE: To investigate the efficacy of dihydromyricetin(DMY) on nasopharyngeal carcinoma(NPC) cell proliferation, apoptosis and to reveal the underlying mechanism in vitro experiments.METHODS: The CNE-2 cell line w...