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How is single-cell RNA sequencing contributing to the advancement of cancer therapeutics?: 《World Journal of Gastrointestinal Oncology》2025年第4期549-552,共4页Keun-Yeong Jeong; The study of Tang et al investigated the distribution and dynamic changes of cell populations in the tumor microenvironment of gastric cancer(GC)patients using single-cell RNA sequencing(scRNA-seq).This comprehensive ...; 关键词：Gastric cancer Single-cell RNA sequencing Tumor microenvironment Clinical trial Anticancer drug candidate

Anticancer properties of beta-caryophyllene and d-limonene terpenes:A review: 《Asian Pacific Journal of Tropical Biomedicine》2025年第4期129-140,共12页Ololade S.Gbadebo Elizabeth D.Oke Felix A.Ajibuwa; Terpenes are a structurally diverse family of secondary metabolites found mostly in plants and microorganisms.Beta-caryophyllene and d-limonene are abundant in aromatic medicinal plants.Beta-caryophyllene can be sourc...; 关键词：ANTICANCER Beta-caryophyllene D-LIMONENE TERPENES Drug discovery APOPTOSIS

Targeted and pH-sensitive polyzwitterionic liposomes for oral anticancer drug delivery: 《Particuology》2025年第3期13-20,共8页Mingyang Hu Rui Zheng Qi Pan Chen Peng Xinyue Zhang Wei He Wenlong Yao Yan Li; financially supported by the Fundamental Research Funds for the Central Universities(grant No.06500230,FRF-BR-23-02B);the National Natural Science Foundation of China(grant No.32071391);the Interdisciplinary Research Project for Young Teachers of USTB(Fundamental Research Funds for the Central Universities,FRF-IDRY-23-019);the Beijing Nova Program(grant No.20230484423).; Compared to intravenous injection,oral administration is attractive due to its many advantages for cancer therapy.Taken physiological barriers and other profiles of oral anticancer drug carriers into consideration,tar...; 关键词：Polyzwitterionic liposomes Poly(carboxybetaine) Doxorubicin hydrochloride Oral administration Cancer therapy

Irreversible electroporation combined with anti-programmed cell death protein 1 therapy promotes tumor antigen-specific CD8+T cell response: 《World Journal of Gastrointestinal Oncology》2025年第3期237-245,共9页Yang-Yang Ma Xiao-Hua Wang Jian-Ying Zeng Ji-Bing Chen Li-Zhi Niu; Science and Technology Program of Guangzhou,No.202102010077;International Science Foundation of Guangzhou Fuda Cancer Hospital,No.Y2020-ZD-03.; BACKGROUND Irreversible electroporation(IRE)is a novel local tumor ablation approach with the potential to activate the host’s immune system.However,this approach is insufficient to prevent cancer progression,and com...; 关键词：Irreversible electroporation Pancreatic cancer Programmed cell death protein 1 blockade CD8+T cell Anticancer immunity

A Multifunctional Nanocatalytic Metal-Organic Framework as a Ferroptosis Amplifier for Mild Hyperthermia Photothermal Therapy: 《Research》2025年第1期517-529,共13页Ying Deng Duo Wang Wenhua Zhao Guanhua Qiu Xiaoqi Zhu Qin Wang Tian Qin Jiali Tang Jinghang Jiang Ningjing Lin Lili Wei Yichen Liu Yuan Xie Jie Chen Liu Deng Junjie Liu; supported by the Postdoctoral Fellowship Program of CPSF[grant number BX20230068];the National Natural Science Foundation of China[grant numbers 82160341 and 82260345];the Natural Science Foundation of Guangxi[grant number 2022GXNSFDA035060];the China Postdoctoral Science Foundation[grant number 2023MD744192];the Key Research and Development Plan of Guangxi[grant number GUIKEAB22080066].; Hyperthermia therapy is considered an effective anticancer strategy.However,high temperature can trigger an excessive inflammatory response,leading to tumor self-protection,immunosuppression,metastasis,and recurrence....; 关键词：hyperthermia therapy anticancer strategyhoweverhigh ferroptosis amplifier mild hyperthermia photothermal therapy multifunctional photothermal nanoplatform ferrocene metal organic framework

Leonurus japonicus:A promising anticancer Chinese medicine modulating regulated cell death: 《Chinese Medical Journal》2025年第3期373-375,共3页Xue Li Mingyu Han Huali Fan Sui Li Fu Peng; To the Editor:According to the latest statistics published by National Cancer Center of China,approximately 4,824,700 cancer cases were newly diagnosed and 2,574,200 patients died from cancer in China in 2022.[1]Uncon...; 关键词：Leonurus japonicus physiological death resistancewhich drug discovery pharmacological activities reprogram cancerous suicide cell proliferation cancer cell death

A novel Au(III)agent designed to inhibit tumor growth and metastasis through inducing immunogenic cell death: 《Rare Metals》2025年第1期430-443,共14页Wen-Juan Li Shan-He Li Xue-Yu Man Gang Xu Zhen-Lei Zhang Yao Zhang Hong Liang Feng Yang; supported by the Natural Science Foundation of Guangxi(No.2022GXNSFGA035003);the National Natural Science Foundation of China(No.22077021).; To treat cancer and inhibit its metastasis to the greatest extent,we proposed to develop an Au(III)agent to induce immunogenic cell death(ICD)and establish long-term immunity.To this end,we optimized a series of Au(II...; 关键词：Gold complex ANTICANCER THIOSEMICARBAZONE Endoplasmic reticulum stress Immunogenic cell death

Recent advances in the bench-to-bedside translation of cancer nanomedicines: 《Acta Pharmaceutica Sinica B》2025年第1期97-122,共26页Yang Liu Yinchao Zhang Huikai Li Tony Y.Hu; supported by the National Natural Science Foundation of China(No.82202603);the Scientific Research Plan Project initiated by the Tianjin Municipal Education Commission(No.2022ZD066,China);the Science and Technology Project of Tianjin Municipal Health Commission(No.TJWJ2021QN008,China).; Cancer remains a complex and challenging medical problem,driving extensive research efforts.Despite significant progress in understanding its genetic and molecular aspects,the quest for effective treatments continues....; 关键词：Cancer nanomedicines Clinical translation Clinical trial landscape ANTICANCER Tumor microenvironment Combination therapies Clinical nanotechnology Drug delivery systems

An In-Depth Examination of Phytochemicals and Medicinal Useson Morus alba: 《Chinese Medicine and Natural Products》2024年第4期137-144,共8页Roshan Kumar Dubey Satyam Shukla Prashant Shukla; Morus alba,commonly known as white mulberry,is a plant renowned for its diverse range of bioactive compounds that confer numerous health benefits.This review explores the plant’s antioxidant,anti-inflammatory,antican...; 关键词：Morus alba white mulberry antioxidant properties anti-inflammatory effects anticancer potential cardiovascular health

Calotropis procera:a review of molecular mechanisms,bioavailability,and potential anticancer property: 《Biomedical Engineering Communications》2024年第4期39-49,共11页Saqib Nawaz Abdul Wajid Asif Nawaz Hanif Ullah Safia Arbab Sawar Khan Aamir Khan Muhammad Sohail Abdul Qadeer; this manuscript sincerely acknowledge Central South University for their support through the postdoctoral research initiation grant(164990011).; Calotropisprocera(Cp)is a traditional medicinal plant that has attracted significant attention for its potential anticancer properties.This review consolidates current research on the Cp bioactive compounds found in C...; 关键词：Calotropisprocera ANTICANCER PI3K/AKT NF-ΚB

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