ATHEROSCLEROSIS

作品数:947被引量:3489H指数:24
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相关领域:医药卫生更多>>
相关作者:雷著斌李文郭春张利宁张一炎更多>>
相关机构:第二军医大学首都医科大学南华大学华中科技大学更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划中国博士后科学基金广东省自然科学基金更多>>
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Calycosin improves atherosclerosis by reshaping the interaction between the gut microbiome and bile acid metabolism
《Food Science and Human Wellness》2025年第4期1369-1386,共18页Jiaqi Fu Donghua Yu Yuqin Liang Xin Gao Yunhe Shi Yu Wang Pingping Chen Fang Lu Shumin Liu 
supported by Heilongjiang Postdoctoral Program(ZHY2022-114);General program of Heilongjiang Province(LBHZ22251);Young Elite Scientists Sponsorship Program(2022-QNRC1-27)。
Calycosin,Astragali Radix most prominent ingredient,has drawn more attention as a result of its ability to treat atherosclerosis(AS).However,the mechanism of action has not been fully elucidated.We investigated the ef...
关键词:CALYCOSIN Atherosderosis Bile acid metabolism Gut microbiota 
Moderate red wine alleviates high-fat diet-induced atherosclerosis in ApoE^(-/-)mice via modulations of liver metabolism through gut microbiota remodeling
《Food Science and Human Wellness》2025年第4期1411-1423,共13页Xuanxuan Chen Hong Yang Kaikai Li Jianhong Cao Xiaoyun Xu Siyi Pan Erhu Li 
the research funds from the National Natural Science Foundation of China(32272294)。
Red wine has a good potential for alleviating atherosclerosis,but the mechanisms related to hepatointestinal circulation remain to be elucidated.This study showed that administration of a high-polyphenol red wine(16 m...
关键词:WINE ATHEROSCLEROSIS Gut microbiota Untargeted metabolomics Short chain fatty acids 
Erratum to:Selenopeptide nanomedicine ameliorates atherosclerosis by reducing monocyte adhesions and inflammations
《Nano Research》2025年第4期659-660,共2页Zhen Luo Yuxing Jiang Zimo Liu Lamei Guo Li Zhang Hongtao Rong Zhongyu Duan Hongwen Liang Aili Zhang Lei Wang Yu Yi Hao Wang 
Erratum to:Nano Research,2024,17(7):6332-6341.https://doi.org/10.1007/s12274-024-6547-z.One of the authors’affiliations,Sino-Danish College,Sino-Danish Center for Education and Research,University of Chinese Academy ...
关键词:inflammations selenopeptide nanomedicine ATHEROSCLEROSIS monocyte adhesions 
Tanyu Tongzhi formula attenuates atherosclerotic plaque vulnerability by inhibiting CD40^(+) monocyte differentiation
《Traditional Medicine Research》2025年第4期61-71,共11页Zheng-Tian Lv Yan-Yun Pan Chen-Xia Wu Yuan-Gang Qiu Shen-Jie Chen Wei Mao Jin Dai 
Natural Science Foundation of Zhejiang Province(grant number LY20H290005);Key Research and Development Program of Zhejiang Province(grant number 2020C03119);National Natural Science Foundation of China(grant numbers 81673706,81973579,82174150);Science and Technology Program of Zhejiang Traditional Chinese Medicine(grant number 2018ZY005);TCM science and Technology Foundation Project of Zhejiang Province(grant number 2023ZL411).
Background:Atherosclerosis(AS)is a chronic progressive inflammatory disease,and plaque stability plays a critical role in preventing acute events.Tanyu Tongzhi formula(TTF),a traditional Chinese medicine,has potential...
关键词:ATHEROSCLEROSIS Tanyu Tongzhi formula CD40^(+)monocyte differentiation inflammation 
ApoL1 risk allele accelerates high-fat diet-induced atherosclerosis in LDLR-/-hamsters
《Genes & Diseases》2025年第2期136-139,共4页Yitong Xu Wenxi Zhang Jiabao Guo Jinxuan Chen Guolin Miao Lianxin Zhang Yufei Han Jingxuan Chen Ying Zhao Xunde Xian 
supported by the National Natural Science Foundation of China (No.82070460,82270479,HY2021-1 to X.Xian);the Fundamental Research Funds for the Central Universities (China) (to X.Xian);the Beijing Natural Science Foundation (No.7242084 to X.Xian).
Apolipoprotein L1(ApoL1),coded by ApoL1 gene that is only expressed in humans,gorillas,and green monkeys,is largely synthesized by the liver and incorporated into highdensity lipoprotein(HDL),playing beneficial,roles ...
关键词:ALLELE INFLAMMATION ATHEROSCLEROSIS 
The Impact of PCSK9 on Risk Factors for Ischemic Stroke and Potential Mechanisms
《American Journal of Molecular Biology》2025年第1期110-122,共13页Zehua He Mingtian Lu Zhejing Ding Zhengwei Chen Tianyang Guan Zhongliang Li Cheng Zhou Haiquan Tao Guangsen Cheng Yu Liu 
Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a member of the proprotein convertase (PCs) family, which facilitates the degradation of low-density lipoprotein receptors (LDL-R) via intracellular and cell su...
关键词:Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Ischemic Stroke ATHEROSCLEROSIS INFLAMMATION 
Development of an atherosclerosis rabbit model to evaluate the hemodynamic impact of extracorporeal circulation
《Animal Models and Experimental Medicine》2025年第3期523-533,共11页Anna Kathrin Assmann Jan Buschmann Sinje Reimers Aleyna Karakas Elvira Weber Hug Aubin Artur Lichtenberg Alexander Assmann 
German Heart Foundation/German Foundation of Heart Research。
Background:Aortic atherosclerosis increases the risk of embolic events under extracorporeal circulation(ECC).To evaluate the hemodynamic impact of ECC on atheromatous plaques,an atherosclerosis animal model,which is a...
关键词:animal model ATHEROSCLEROSIS CALCIFICATION extracorporeal circulation INFLAMMATION PLAQUES 
Association between serum retinol-binding protein and lower limb atherosclerosis risk in type 2 diabetes mellitus
《World Journal of Diabetes》2025年第3期76-88,共13页Yu-Ling Zhang Gui-Liang Peng Wei-Ling Leng Yu Lian Li-Qing Cheng Xing Li Yu-Lin Wang Ling Zhou Min Long 
The study was approved by the ethics committee of Southwest Hospital,the First Affiliated Hospital of Army Medical University of Chinese People's Liberation Army(No.KY2024007).
BACKGROUND Serum retinol-binding protein(RBP)is the primary transport protein of circulating vitamin A.RBP has a crucial role in maintaining nutrient metabolism and physiologic homeostasis.Several studies have indicat...
关键词:Retinol-binding protein Type 2 diabetes mellitus Lower limb atherosclerosis Peripheral arterial disease BIOMARKER 
Circulating metabolites of Borneolum syntheticum(Bingpian)ameliorate atherosclerosis in ApoE−/−mice via inhibiting macrophage foam-cell formation
《Acta Pharmacologica Sinica》2025年第3期759-776,共18页Rong-rong He Chuan-rui Ma Xin He Yan-xi Dong Hui Li Zi-xuan Chu Xi-he Yang Jia-qi Wang Ting Wang Feng-qing Wang Fei-fei Du Ying Rao Wen-xuan Yu Xiu-mei Gao Guan-wei Fan Chen Cheng Chuan Li 
funded by grants from the National Natural Science Foundation of China(82192912);National Engineering Research Center of TCM Standardization Technology(2023-ZYBZH-10);National Key R&D Program“Strategic Scientific and Technological Innovation Cooperation”Key Project(2022YFE0203600).
Translational pharmacological research on traditional medicines lays the foundation for precisely understanding how the medicines function in the body to deliver therapeutic benefits.Borneolum syntheticum(Bingpian)is ...
关键词:Borneolum syntheticum Bingpian BORNEOL ISOBORNEOL metabolism ATHEROSCLEROSIS 
Effect of herb cake-insulated moxibustion on serum exosomal miR-223 expression in rabbits with atherosclerosis
《Journal of Acupuncture and Tuina Science》2025年第1期12-21,共10页LI Qian PENG Han CHEN Xinyu YI Hongfen GE Junyun OUYANG Lizhi LIU Honghua LIU Mailan 
国家自然科学基金项目,No.81704182,No.82074559;长沙市杰出创新青年培养计划项目,No.kq1905036;湖南省青年科技创新人才项目,No.2022RC1222;2022年湖南中医药大学研究生创新课题,No.2022CX111。
Objective:To investigate whether herb cake-insulated moxibustion affects the expression of cholesterol metabolismrelated protein 3-hydroxy-3-methylglutaryl coenzyme A reductase(HMGR)and inhibits the development of ath...
关键词:Moxibustion Therapy Herb Cake-insulated Moxibustion ATHEROSCLEROSIS 3-hydroxy-3-methylglutaryl Coenzyme A Reductase Embolism Cholesterol Exosomes RABBITS 
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