supported by Heilongjiang Postdoctoral Program(ZHY2022-114);General program of Heilongjiang Province(LBHZ22251);Young Elite Scientists Sponsorship Program(2022-QNRC1-27)。
Calycosin,Astragali Radix most prominent ingredient,has drawn more attention as a result of its ability to treat atherosclerosis(AS).However,the mechanism of action has not been fully elucidated.We investigated the ef...
the research funds from the National Natural Science Foundation of China(32272294)。
Red wine has a good potential for alleviating atherosclerosis,but the mechanisms related to hepatointestinal circulation remain to be elucidated.This study showed that administration of a high-polyphenol red wine(16 m...
Erratum to:Nano Research,2024,17(7):6332-6341.https://doi.org/10.1007/s12274-024-6547-z.One of the authors’affiliations,Sino-Danish College,Sino-Danish Center for Education and Research,University of Chinese Academy ...
Natural Science Foundation of Zhejiang Province(grant number LY20H290005);Key Research and Development Program of Zhejiang Province(grant number 2020C03119);National Natural Science Foundation of China(grant numbers 81673706,81973579,82174150);Science and Technology Program of Zhejiang Traditional Chinese Medicine(grant number 2018ZY005);TCM science and Technology Foundation Project of Zhejiang Province(grant number 2023ZL411).
Background:Atherosclerosis(AS)is a chronic progressive inflammatory disease,and plaque stability plays a critical role in preventing acute events.Tanyu Tongzhi formula(TTF),a traditional Chinese medicine,has potential...
supported by the National Natural Science Foundation of China (No.82070460,82270479,HY2021-1 to X.Xian);the Fundamental Research Funds for the Central Universities (China) (to X.Xian);the Beijing Natural Science Foundation (No.7242084 to X.Xian).
Apolipoprotein L1(ApoL1),coded by ApoL1 gene that is only expressed in humans,gorillas,and green monkeys,is largely synthesized by the liver and incorporated into highdensity lipoprotein(HDL),playing beneficial,roles ...
Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a member of the proprotein convertase (PCs) family, which facilitates the degradation of low-density lipoprotein receptors (LDL-R) via intracellular and cell su...
German Heart Foundation/German Foundation of Heart Research。
Background:Aortic atherosclerosis increases the risk of embolic events under extracorporeal circulation(ECC).To evaluate the hemodynamic impact of ECC on atheromatous plaques,an atherosclerosis animal model,which is a...
The study was approved by the ethics committee of Southwest Hospital,the First Affiliated Hospital of Army Medical University of Chinese People's Liberation Army(No.KY2024007).
BACKGROUND Serum retinol-binding protein(RBP)is the primary transport protein of circulating vitamin A.RBP has a crucial role in maintaining nutrient metabolism and physiologic homeostasis.Several studies have indicat...
funded by grants from the National Natural Science Foundation of China(82192912);National Engineering Research Center of TCM Standardization Technology(2023-ZYBZH-10);National Key R&D Program“Strategic Scientific and Technological Innovation Cooperation”Key Project(2022YFE0203600).
Translational pharmacological research on traditional medicines lays the foundation for precisely understanding how the medicines function in the body to deliver therapeutic benefits.Borneolum syntheticum(Bingpian)is ...
Objective:To investigate whether herb cake-insulated moxibustion affects the expression of cholesterol metabolismrelated protein 3-hydroxy-3-methylglutaryl coenzyme A reductase(HMGR)and inhibits the development of ath...