funded by grants from the National Natural Science Foundation of China(82192912);National Engineering Research Center of TCM Standardization Technology(2023-ZYBZH-10);National Key R&D Program“Strategic Scientific and Technological Innovation Cooperation”Key Project(2022YFE0203600).
Translational pharmacological research on traditional medicines lays the foundation for precisely understanding how the medicines function in the body to deliver therapeutic benefits.Borneolum syntheticum(Bingpian)is ...
supported by National Key R&D Program of China(2020YFA0908000);the CACMS Innovation Fund(CI2021A04109,CI2023D002,China);Key project at central government level:the ability to establish sustainable use of valuable Chinese Medicine Resources(2060302,China).
(+)-Borneol,the main component of"Natural Borneol"in the Chinese Pharmacopoeia,is a high-end spice and precious medicine.Plant extraction cannot meet the increasing demand for(+)-borneol,while microbial biosynthesis o...
supported by National Natural Science Foundation of China(U23A20513);the Fundamental Research Funds for the Central Public Welfare Research Institutes(ZZ14-YQ-049);National Natural Science Foundation of China(82274054);Key project at central government level:the ability to establish sustainable use of valuable Chinese Medicine Resources(2060302).
Background:Ophiopogon japonicus(L.f)Ker-Gawl.growing in Zhejiang is recognized as the Dao-di medicinal herb for the production of Ophiopogonis Radix.Borneol-7-O-[β-D-apiofuranosyl-(1→6)]-β-D-glucopyranoside,a promi...
National Natural Science Foundation of China[grant number 82203906];Guangdong Basic and Applied Basic Research Foundation[grant number 2022A1515012020];Project of Guangzhou Science and Technology[grant number 202201020355].
Psoriasis,an immune-mediated inflammatory skin disorder characterized by a chronically relapsing-remitting course,continues to be primarily managed through topical therapy.While oral administration of tyrosine kinase ...
BACKGROUND Toxic epidermal necrolysis(TEN)is a life-threatening dermatological emergency mainly induced by drug hypersensitivity reactions.Standard management includes discontinuation of culprit drug and application o...
Borneol, as a traditional natural permeation enhancer, has been widely used to promote the transdermal absorption of active ingredients. In this review, the mechanism of borneol in promoting permeation by destroying t...
This work was supported by Project of Natural Science Foundation of Shandong province(No.ZR2020MH343).
Background:Compatibility is a characteristic of the clinical application of traditional Chinese medicine,often leading to enhanced therapeutic effects.In the treatment of cerebral ischemia,blood-activating and open or...
Borneol,as a traditional natural permeation enhancer,has been widely used to promote the transdermal absorption of active ingredients.The mechanism of borneol in promoting permeation by destroying the highly ordered l...
supported by the Distinguished Professor Project of Liaoning Province.
The number of people with Alzheimer’s disease(AD)is increasing annually,with the nidus mainly concentrated in the cortex and hippocampus.Despite of numerous efforts,effective treatment of AD is still facing great cha...
Objective: To explore the effect of Bismuth Subgallate/Borneol (SuileTM BSB) healing dressing combined with autologous platelet-rich gel (APG) in the treatment of diabetic foot ulcer (DFU). Methods: A total...