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BIOMARKER: 作品数：1378被引量：6483H指数：29; 导出分析报告; 相关领域：医药卫生生物学更多>>; 相关作者：段秀枝李从荣王书奎李艳顾剑更多>>; 相关机构：第二军医大学南方医科大学南方医院复旦大学天津市肿瘤医院更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划国家教育部博士点基金北京市自然科学基金更多>>

P2X7 receptors and multiple sclerosis: A potential biomarker and therapeutic target?: 《Neural Regeneration Research》2026年第1期318-319,共2页Cristina Agliardi Franca Rosa Guerini Mario Clerici; supported by Italian Ministry of Health Ricerca Corrente [RC 2023] and RF-2016-02361294;supported by#NEXTGENERATIONEU (NGEU);funded by the Ministry of University and Research (MUR);National Recovery and Resilience Plan (NRRP);project MNESYS (PE0000006)–A Multiscale integrated approach to the study of the nervous system in health and disease (DN. 1553 11.10.2022)(to FRG);partially supported by a grant from Fondazione Romeo ed Enrica Invernizzi (to FRG)。; Multiple sclerosis(MS) is a chronic, autoimmune and neuroinflammatory disease of the central nervous system(CNS) with a neurodegenerative component, characterized by demyelination and degeneration of nerve fibers. It ...; 关键词：SCLEROSIS DEGENERATION THERAPEUTIC

Autism spectrum disorder:difficulties in diagnosis and microRNA biomarkers: 《Neural Regeneration Research》2025年第10期2776-2786,共11页Bridget Martinez Philip V.Peplow; We performed a PubMed search for microRNAs in autism spectrum disorder that could serve as diagnostic biomarkers in patients and selected 17 articles published from January 2008 to December 2023,of which 4 studies wer...; 关键词：autism spectrum disorder BIOMARKER blood cells blood plasma blood serum DIAGNOSIS MICRORNA peripheral blood mononuclear cells serum neural cell adhesion molecule L1-captured extracellular vesicles whole blood

Blood diagnostic and prognostic biomarkers in amyotrophic lateral sclerosis被引量：1: 《Neural Regeneration Research》2025年第9期2556-2570,共15页Yongting Lv Hongfu Li; Amyotrophic lateral sclerosis is a devastating neurodegenerative disease for which the current treatment approaches remain severely limited.The principal pathological alterations of the disease include the selective d...; 关键词：amyotrophic lateral sclerosis BIOMARKER blood biomarkers diagnosis glial fibrillary acidic protein neurofilament light chain PROGNOSIS TAR DNA-binding protein 43

Decreased levels of phosphorylated synuclein in plasma are correlated with poststroke cognitive impairment: 《Neural Regeneration Research》2025年第9期2598-2610,共13页Yi Wang Yuning Li Yakun Gu Wei Ma Yuying Guan Mengyuan Guo Qianqian Shao Xunming Ji Jia Liu; supported by the Scientific Research Project of China Rehabilitation Research Center,No.2021zx-23;the National Natural Science Foundation of China,No.32100925;the Beijing Nova Program,No.Z211100002121038。; Poststro ke cognitive impairment is a major secondary effect of ischemic stroke in many patients;however,few options are available for the early diagnosis and treatment of this condition.The aims of this study were to...; 关键词：BIOMARKER high-density lipoprotein ischemic stroke phosphorylatedα-synuclein poststroke cognitive impairment

Total adenosine deaminase cases as an inflammatory biomarker of pleural effusion syndrome: 《World Journal of Clinical Cases》2025年第19期14-23,共10页Bernardo Henrique Ferraz Maranhão Cyro Teixeira da Silva Junior Jorge Luiz Barillo Joeber Bernardo Soares Souza Patricia Siqueira Silva Roberto Stirbulov; BACKGROUND Although inflammatory diseases commonly affect the pleura and pleural space,their mechanisms of action remain unclear.The presence of several mediators emphasizes the concept of pleural inflammation.Adenosi...; 关键词：Pleural effusion BIOMARKER Adenosine deaminase INFLAMMATION transudate EXUDATE

Tired of the confusion around pleural effusions:Adenosine deaminase detection sets the record straight!: 《World Journal of Clinical Cases》2025年第21期1-5,共5页Kai-Yan Liu Xiao-Bing Li; Pleural effusion,characterized by the accumulation of fluid in the pleural space,poses significant challenges in clinical practice,especially in determining whether it belongs to the inflammatory exudates or non-infla...; 关键词：Pleural effusion Pleural inflammation Diagnosis BIOMARKER Adenosine deaminase

MicroRNAs as potential biomarkers for diagnosis of post-traumatic stress disorder: 《Neural Regeneration Research》2025年第7期1957-1970,共14页Bridget Martinez Philip V.Peplow; Post-traumatic stress disorder is a mental disorder caused by exposure to severe traumatic life events.Currently,there are no validated biomarkers or laboratory tests that can distinguish between trauma survivors with...; 关键词：BIOMARKER DIAGNOSIS microRNA peripheral blood mononuclear cells plasma extracellular vesicles/exosomes post-traumatic stress disorder serum exosomes whole blood whole plasma

Peripheral mitochondrial DNA as a neuroinflammatory biomarker for major depressive disorder: 《Neural Regeneration Research》2025年第6期1541-1554,共14页Jinmei Ye Cong Duan Jiaxin Han Jinrong Chen Ning Sun Yuan Li Tifei Yuan Daihui Peng; supported by the National Natural Science Foundation of China,No.81971269 (to DP);the Science and Technology Commission of Shanghai,No.YDZX20213100001003 (to DP)。; In the pathogenesis of major depressive disorder, chronic stress-related neuroinflammation hinders favorable prognosis and antidepressant response. Mitochondrial DNA may be an inflammatory trigger, after its release f...; 关键词：BIOMARKER cytokine EXOSOMES INFLAMMASOME major depressive disorder MICROGLIA mitochondrial DNA mitochondrial dysfunction NEUROINFLAMMATION Toll-like receptor

MicroRNAs as potential diagnostic biomarkers for bipolar disorder: 《Neural Regeneration Research》2025年第6期1681-1695,共15页Bridget Martinez Philip V.Peplow; Abnormal expression of microRNAs is connected to brain development and disease and could provide novel biomarkers for the diagnosis and prognosis of bipolar disorder. We performed a PubMed search for microRNA biomarke...; 关键词：BIOMARKER bipolar disorder blood leukocytes blood plasma blood plasma extracellular vesicles/exosomes blood serum brain tissue brain tissue extracellular vesicles/exosomes lymphoblastoid cell lines MICRORNA neural progenitor cells whole blood

N‑terminal pro‑brain natriuretic peptide–a significant biomarker of disease development and adverse prognosis in patients with exertional heat stroke: 《Military Medical Research》2025年第3期461-463,共3页Long Feng Jian-Yuan Yin Yao-Hong Liu Pei Zhang Ya-Li Zhao Qing Song Ping Ping Shi-Hui Fu; supported by the Natural Science Foundation of Hainan Province(821QN389,821MS112,822MS198,820MS126,820QN383);the Military Medical Science and Technology Youth Incubation Program(20QNPY110,19QNP060);the Excellent Youth Incubation Program of Chinese PLA General Hospital(2020-YQPY-007);the Heatstroke Treatment and Research Center of Chinese PLA(413EGZ1D10);the Simulation Training for Treatment of Heatstroke,the Major Science and Technology Programme of Hainan Province(ZDKJ2019012);the National Key Research and Development Program of China(2018YFC2000400);the National S&T Resource Sharing Service Platform Project of China(YCZYPT[2018]07);the Specific Research Fund of Innovation Platform for Academicians of Hainan Province(YSPTZX202216);the Medical Big Data Research and Development Project of Chinese PLA General Hospital(MBD2018030).; Dear Editor,The most serious heat related injury is exertional heat stroke(EHS).EHS occurs when healthy individuals perform physical activity in a hot and humid environment[1].A disrupted balance between heat producti...; 关键词：Exertional heat stroke MORTALITY Myocardial enzymes N-terminal pro-brain natriuretic peptide(NTproBNP) Physical activity

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