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作品数:111被引量:193H指数:8
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相关领域:医药卫生更多>>
相关作者:张璐孙燕官阳戴甲培何敬更多>>
相关机构:南方医科大学华中科技大学阿姆斯特丹大学中南民族大学更多>>
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相关基金:国家自然科学基金中国博士后科学基金北京市自然科学基金高等学校学科创新引智计划更多>>
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Is it possible to maintain a plaque-free healthy brain by treadmill?
《Neural Regeneration Research》2025年第12期3525-3526,共2页Swarupa Pahan Kalipada Pahan 
supported by merit awards (1I01BX005002 and I01BX005613) from US Department of Veterans Affairs;a grant (AT10980) from NIH (to KP)。
It is believed that overproduction and deposition of amyloid-β (Aβ) plaques in the hippocampus and cortex region of the brain cause neuronal dysfunction leading to cognitive impairments in Alzheimer’s disease (AD)....
关键词:CORTEX  PLAQUES 
Effect of systolic blood pressure status on coronary inflammation and high-risk plaque characteristics
《World Journal of Diabetes》2025年第4期128-143,共16页Cui-Ping Jiang Yuan-Kang Liu Pan-Pan Cheng Yue Dong Xiang Wang Fan-Yu Wu Yu-Xuan Xia Peng-Yun Wang Xiang-Yang Xu 
Supported by Natural Science Foundation of Hubei Province,No.2023AFB848.
BACKGROUND Inadequately controlled hypertension often leads to an increased cardiovascular death rate in type 2 diabetes mellitus(T2DM).It remains unclear whether systolic blood pressure(SBP)status of hypertension is ...
关键词:Type 2 diabetes mellitus HYPERTENSION Coronary computed tomography angiography Pericoronary adipose tissue attenuation High-risk plaques 
Aggregation-Induced Emission-Active Photosensitizer-Mediated Photodynamic Therapy for Anti-Psoriasis
《Research》2025年第1期935-954,共20页Ping Zhu Zhaoji Wu Zhilu Yang Tingting Tang Yunhui Liao Wen Zhao Ying Huang Tao Chen Junjie Li Chunmei Nong Zhenzhen Wu Guodong Hu Yanshan Liu Yinghua Chen 
supported by the Natural Science Funding of Guangdong Province(2022A1515012312 and 2021A1515010023);the National Natural Science Funding of China(82070083);Dongguan Social development technology projects Science and Technology Planning Project(20231800940792).
Hyperproliferative keratinocytes and subcutaneous inflammation contribute to the characteristic symptoms of psoriasis,including erythema,scales,or scaly plaques on the skin.These symptoms significantly affect patients...
关键词:PSORIASIS PHOTOSENSITIZER hyperproliferative keratinocytes subcutaneous inflammation scaly plaques organic photosensitizer photodynamic therapy treatment strategies 
Development of an atherosclerosis rabbit model to evaluate the hemodynamic impact of extracorporeal circulation
《Animal Models and Experimental Medicine》2025年第3期523-533,共11页Anna Kathrin Assmann Jan Buschmann Sinje Reimers Aleyna Karakas Elvira Weber Hug Aubin Artur Lichtenberg Alexander Assmann 
German Heart Foundation/German Foundation of Heart Research。
Background:Aortic atherosclerosis increases the risk of embolic events under extracorporeal circulation(ECC).To evaluate the hemodynamic impact of ECC on atheromatous plaques,an atherosclerosis animal model,which is a...
关键词:animal model ATHEROSCLEROSIS CALCIFICATION extracorporeal circulation INFLAMMATION PLAQUES 
Novel mouse model of Alzheimer's disease exhibits pathology through synergistic interactions among amyloid-β,tau,and reactive astrogliosis
《Zoological Research》2025年第1期41-53,共13页Young-Eun Han Sunhwa Lim Seung Eun Lee Min-Ho Nam Soo-Jin Oh 
supported by the National Research Foundation of Korea (NRF)funded by the Ministry of Science,ICT&Future Planning (2022R1A2C2006229,2022R1A6A3A01086868);Korea Dementia Research Project through the Korea Dementia Research Center (KDRC)funded by the Ministry of Health&Welfare and Ministry of Science and ICT,Republic of Korea (RS-2024-00345328);KIST Institutional Grant (2E32851)。
Alzheimer'sdisease(AD)isaprogressive neurodegenerative disorder characterized by cognitive impairment and distinct neuropathological features,including amyloid-βplaques,neurofibrillary tangles,and reactive astroglios...
关键词:Alzheimer's disease mouse model Neurofibrillary tangles Amyloid-βplaques Reactive astrogliosis Alzheimer’s disease pathology 
OJU Peyronie’s Disease in an Elderly Ghanaian Gentleman—A Case-Report and Literature Review
《Open Journal of Urology》2024年第10期519-531,共13页Frank Obeng Aishah Fadila Adamu Samuel Edudzi Gavor Blessings Yao Setsoafia Sedem Atimpo Ebenezer Antwi Enoch Kwaku Adjaho Nana Yaa Agyenim Boateng Merveille Adjin Anum-Laryea Gwendolyn Egyefi Armah Juliet Enyonam Dzivenu Frank Fosu Joel Kwame Kwao Alexander Kofi Quansah Pearl Esi Demawu Hussein Rachel Akosua Sogbe Kafui Kossi Kekessie Mawuenyo Attawa Oyortey Ali Mamudu Ayamba 
Background: Peyronie’s disease is characterized by fibrous plaque formation in the tunica albuginea, leading to penile curvature and sexual dysfunction. Surgical correction is often required in cases of severe deform...
关键词:Peyronie’s Disease Penile Trauma Tunica Albuginea Penile Deformity Sexual Frustration Careful Diagnosis Tailored-Surgical Therapy Calcific-Plaques Autologous Fascia Lata Graft Water-Tight Repair 
Early Syphilis Presenting as Thickened Penile Plaques With an Embedded Recurrent Ulcer (Chancre Redux): A Case Report
《International Journal of Dermatology and Venereology》2024年第3期160-162,共3页Stephen C.Davies Rodney Hannaford Joseph Cotter 
Introduction:The manifestations of syphilis are varied,and serology can establish the diagnosis early,especially in rare cases.We report a case of chancre redux(a rare recurrence of primary syphilis),which was embedde...
关键词:primary syphilis secondary syphilis chancre redux immunohistochemistry IMMUNOPEROXIDASE genital rash 
Characterization of non‐calcified predominant plaque using deep learning and radiomics analyses of coronary computed tomography angiography images
《iRADIOLOGY》2024年第3期260-263,共4页Xin Jin Yuze Li Fei Yan Tao Li Xinghua Zhang Ye Liu Li Yang Huijun Chen 
Background:To use an automated system exploiting the advantages of both a neural network and radiomics for analysis of non‐calcified predominant pla-que(NCPP).Methods:This study retrospectively included 234 patients....
关键词:atherosclerosis PLAQUES radiomics CORONARY COMPUTED tomography ANGIOGRAPHY 
Human Papillomavirus Within Psoriasis Plaques in a Patient With Psoriasis:A Case Report
《International Journal of Dermatology and Venereology》2024年第1期55-57,共3页Karen P.Lema-Matehu Nathalie P.Lascano-Gallegos Santiago A.Palacios-Álvarez 
Introduction:Psoriasis may be triggered by several factors,and its pathophysiology is related to inflammatory cellular processes.We herein describe a patient with psoriasis who developed warts on multiple psoriasis pl...
关键词:human papillomavirus METHOTREXATE PSORIASIS case report 
Biomimetic nanomedicines for precise atherosclerosis theranostics被引量:2
《Acta Pharmaceutica Sinica B》2023年第11期4442-4460,共19页Ying Tao Xinmiao Lan Yang Zhang Chenxing Fu Lu Liu Feng Cao Weisheng Guo 
partially supported by grants from the National Natural Science Foundation of China (No.31971302,China);the Natural Science Foundation of Guangdong Province of China (No.2019A1515011597,China);the talent young scientist supporting program of China Association for Science and Technology;the Educational Commission of Guangdong Province of China Key Project (No.2020ZDZX2001,China);the joint grant between Guangzhou City and College (No.202102010106,China)。
Atherosclerosis(AS)is a leading cause of the life-threatening cardiovascular disease(CVD),creating an urgent need for efficient,biocompatible therapeutics for diagnosis and treatment.Biomimetic nanomedicines(b NMs)are...
关键词:Nanotheranostics ATHEROSCLEROSIS Biomimetic nanomedicines Drug delivery Passive targeting Active targeting PLAQUES Diagnosis and treatment 
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