Is it possible to maintain a plaque-free healthy brain by treadmill?  

作　　者：Swarupa Pahan Kalipada Pahan 

机构地区：[1]Division of Research and Development,Jesse Brown Veterans Affairs Medical Center,Chicago,IL,USA [2]Department of Neurological Sciences,Rush University Medical Center,Chicago,IL,USA

出　　处：《Neural Regeneration Research》2025年第12期3525-3526,共2页中国神经再生研究(英文版)

基　　金：supported by merit awards (1I01BX005002 and I01BX005613) from US Department of Veterans Affairs;a grant (AT10980) from NIH (to KP)。

摘　　要：It is believed that overproduction and deposition of amyloid-β (Aβ) plaques in the hippocampus and cortex region of the brain cause neuronal dysfunction leading to cognitive impairments in Alzheimer’s disease (AD).Until now,there has been no effective treatment to reduce plaque load from the brain.Recent studies have shown that regular treadmill exercise lowers plaques from the brain of a mouse model of AD.

关 键 词：CORTEX Aβ PLAQUES 

分 类 号：R749.16[医药卫生—神经病学与精神病学]