TRANSTHYRETIN

作品数:40被引量:70H指数:4
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相关领域:医药卫生更多>>
相关作者:朴颖孙晴晴张国辉吴小丹王赞更多>>
相关机构:天津医科大学吉林大学第一医院癌症研究所上海市肿瘤研究所更多>>
相关期刊:《World Journal of Clinical Cases》《Translational Neurodegeneration》《Chinese Journal of Integrative Medicine》《Science China Chemistry》更多>>
相关基金:国家自然科学基金天津市应用基础与前沿技术研究计划更多>>
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Effect of L-theanine combined with geniposide on depression-like behavior induced by the chronic unpredictable mild stress(CUMS)in mice
《Food Science and Human Wellness》2025年第4期1424-1440,共17页Qiming Yu Yan Zhu Tao Jiang Ying Gao Nan Ling Na Wang John Shi Weichun Pan Qizhen Du Junfeng Yin 
funded by Innovation Project for Chinese Academy of Agricultural Sciences(CAAS-ASTIP-TRI);China Agriculture Research System of MOF and MARA(CARS-19)。
Depression is a prevalent mental disorder with limited effective treatments,posing a significant global issue.This study explored L-theanine and geniposide,key components in“food-medicine homology”materials,to deter...
关键词:CUMS DEPRESSION L-THEANINE GENIPOSIDE TRANSTHYRETIN 
Design and redesign journey of a drug for transthyretin amyloidosis
《Neural Regeneration Research》2025年第4期1096-1097,共2页Francisca Pinheiro Salvador Ventura 
funded by the Spanish Ministry of Science and Innovation(PDC2021-120914-I00);the Universitat Autònoma de Barcelona(PROOF OF CONCEPT 2020);ICREA,ICREA-Academia 2015 and 2020(to SV).
The misfolding and subsequent aggregation of proteins into amyloid fibrils underlie the onset of a variety of human disorders collectively known as amyloidosis.Transthyretin(TTR)is one of the>30 amyloidogenic proteins...
关键词:AMYLOID aggregation SENILE 
Binding interaction of typical emerging contaminants on Gobiocypris rarus transthyretin:an in vitro and in silico study
《Frontiers of Environmental Science & Engineering》2024年第11期53-64,共12页Xiangqiao Li Huihui Liu Songshan Zhao Peter Watson Xianhai Yang 
supported by the National Natural Science Foundation of China(No.22176097);the Fundamental Research Funds for the Central Universities(China)(No.30923011032).
Emerging contaminants(ECs)have drawn global concern,and the endocrine disrupting chemicals is one of the highly interested ECs categories.However,numerous ECs lacks the basic information about whether they can disturb...
关键词:Endocrine disrupting effects Hormone transporter Endocrine disrupting chemicals Disinfection byproducts Classification model 
Carpal Tunnel Syndrome: A Marker for Amyloidosis
《World Journal of Neuroscience》2024年第3期92-101,共10页Luciana León Cejas Miguel Saucedo Mayra Aldecoa Gustavo Teruya Fabricio Silva Alvaro Muratore Gonzalo Viollaz Cintia Marchesoni Ana Pardal Pablo Dezanzo Alejandro Iotti Ricardo Reisin 
Introduction: Amyloidosis are systemic conditions and carpal tunnel syndrome (CTS) precedes the principal systemic complications and can be used as an early marker. Our objective was to determine the frequency of amyl...
关键词:Carpal Tunnel AMYLOID TRANSTHYRETIN Amyloid Cardiac Transthyretin Variants Light Chains 
Recent advances in the diagnostic methods and therapeutic strategies of transthyretin cardiac amyloidosis
《World Journal of Cardiology》2024年第7期370-379,共10页Christos Kourek Alexandros Briasoulis Dimitrios E Magouliotis Panagiotis Georgoulias Grigorios Giamouzis Filippos Triposkiadis John Skoularigis Andrew Xanthopoulos 
Cardiac amyloidosis is a progressive disease characterized by the buildup of amyloid fibrils in the extracellular space of the heart.It is divided in 2 main types,immunoglobulin light chain amyloidosis and transthyret...
关键词:Transthyretin cardiac amyloidosis Tafamidis Acoramidis Eplontersen Vutrisiran Patisiran 
Rare manifestation of familial vitreous amyloidosis caused by Gly103Arg transthyretin
《International Journal of Ophthalmology(English edition)》2023年第7期1093-1099,共7页Yan-Bing Feng Yan-Bo Shi Yan-Yan He Zhen-Yi Ma Yi-Xing Zhu Wen-Qing Weng 
Supported by Zhejiang Provincial Health Science and Technology Program of Traditional Chinese Medicine(No.2021ZB284,No.2023ZR053);Science and Technology Bureau of Jiaxing City(No.2021AY30007,No.2021AY30008);Jiaxing Key Laboratory of Diabetic Angiopathy Research(No.2019ZDSYS)。
AIM:To identify and analyze the genotype of the patients with special ocular manifestations of familial vitreous amyloidosis(FVA)in a Chinese Han family.METHODS:Pars plana vitrectomy(PPV)surgery was performed on a 52-...
关键词:familial vitreous amyloidosis transthyretin gene Gly103Arg vascular endothelial growth factor 
Screening for Transthyretin Cardiac Amyloidosis in Patients with Bilateral Carpal Tunnel Syndrome: Identifying Missed Opportunities for Early Detection and Treatment
《World Journal of Cardiovascular Diseases》2023年第7期366-376,共11页Ayman Alsaadi Renato Cerna-Viacava Liyan Obeidat Shing Chao Johnathan Stephan Charles S. Day Jennifer Cowger Celeste Williams Karthikeyan Ananthasubramaniam 
Purpose: Transthyretin cardiac amyloidosis (ATTR-CA) has been linked to many extra-cardiac manifestations including bilateral carpal tunnel syndrome (CTS). The aim of this study is to analyze patients with bilateral C...
关键词:Bilateral Carpal Tunnel Syndrome MORALITY PREVALENCE Red Flags Transthyretin Cardiac Amyloidosis 
Roles of constitutively secreted extracellular chaperones in neuronal cell repair and regeneration
《Neural Regeneration Research》2023年第4期769-772,共4页Sandeep Satapathy Mark R.Wilson 
Protein quality control involves many processes that jointly act to regulate the expression, localization, turnover, and degradation of proteins, and has been highlighted in recent studies as critical to the different...
关键词:cell viability CLUSTERIN extracellular chaperones inflammation NEUROSERPIN protein misfolding TRANSTHYRETIN Α2-MACROGLOBULIN 
A misdiagnosed transthyretin in an elderly with myocardial hypertrophy and atrioventricular block:a case report
《Journal of Geriatric Cardiology》2023年第2期150-154,共5页Ming-Yue XU Wei HUANG Kan ZHANG Dai ZHANG Yun-Li XING 
Cardiac amyloidosis(CA)is an infiltrative and restrictive cardiomyopathy that leads to heart failure(HF),decreased quality of life,and death.[1–3]There are two main subtypes of the disease,transthyretin cardiac amylo...
关键词:AMYLOID CARDIOMYOPATHY CARDIAC 
Clinical features of retinal amyloid angiopathy with transthyretin Gly83Arg variant被引量:1
《International Journal of Ophthalmology(English edition)》2023年第1期128-134,共7页Gang Su Xing-Wang Chen Jun-Lin Pan Hong Li Bing Xie Shan-Jun Cai 
Supported by the National Natural Science Foundation of China(No.31871261);the Guizhou Science and Technology Cooperation Foundation[No.ZK(2021)general 423];the Research Initiation Fund for Masters in Affiliated Hospital of Zunyi Medical University(No.2016-43)。
AIM:To report on the clinical features of patients with retinal amyloid angiopathy(RAA)who were identified to be caused by the transthyretin(TTR)Gly83Arg variant.METHODS:Case series of five patients diagnosed with RAA...
关键词:retinal amyloid angiopathy hereditary transthyretin amyloidosis fundus fluorescein angiography VITRECTOMY retinal photocoagulation 
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