funded by Innovation Project for Chinese Academy of Agricultural Sciences(CAAS-ASTIP-TRI);China Agriculture Research System of MOF and MARA(CARS-19)。
Depression is a prevalent mental disorder with limited effective treatments,posing a significant global issue.This study explored L-theanine and geniposide,key components in“food-medicine homology”materials,to deter...
funded by the Spanish Ministry of Science and Innovation(PDC2021-120914-I00);the Universitat Autònoma de Barcelona(PROOF OF CONCEPT 2020);ICREA,ICREA-Academia 2015 and 2020(to SV).
The misfolding and subsequent aggregation of proteins into amyloid fibrils underlie the onset of a variety of human disorders collectively known as amyloidosis.Transthyretin(TTR)is one of the>30 amyloidogenic proteins...
supported by the National Natural Science Foundation of China(No.22176097);the Fundamental Research Funds for the Central Universities(China)(No.30923011032).
Emerging contaminants(ECs)have drawn global concern,and the endocrine disrupting chemicals is one of the highly interested ECs categories.However,numerous ECs lacks the basic information about whether they can disturb...
Introduction: Amyloidosis are systemic conditions and carpal tunnel syndrome (CTS) precedes the principal systemic complications and can be used as an early marker. Our objective was to determine the frequency of amyl...
Cardiac amyloidosis is a progressive disease characterized by the buildup of amyloid fibrils in the extracellular space of the heart.It is divided in 2 main types,immunoglobulin light chain amyloidosis and transthyret...
Supported by Zhejiang Provincial Health Science and Technology Program of Traditional Chinese Medicine(No.2021ZB284,No.2023ZR053);Science and Technology Bureau of Jiaxing City(No.2021AY30007,No.2021AY30008);Jiaxing Key Laboratory of Diabetic Angiopathy Research(No.2019ZDSYS)。
AIM:To identify and analyze the genotype of the patients with special ocular manifestations of familial vitreous amyloidosis(FVA)in a Chinese Han family.METHODS:Pars plana vitrectomy(PPV)surgery was performed on a 52-...
Purpose: Transthyretin cardiac amyloidosis (ATTR-CA) has been linked to many extra-cardiac manifestations including bilateral carpal tunnel syndrome (CTS). The aim of this study is to analyze patients with bilateral C...
Protein quality control involves many processes that jointly act to regulate the expression, localization, turnover, and degradation of proteins, and has been highlighted in recent studies as critical to the different...
Cardiac amyloidosis(CA)is an infiltrative and restrictive cardiomyopathy that leads to heart failure(HF),decreased quality of life,and death.[1–3]There are two main subtypes of the disease,transthyretin cardiac amylo...
Supported by the National Natural Science Foundation of China(No.31871261);the Guizhou Science and Technology Cooperation Foundation[No.ZK(2021)general 423];the Research Initiation Fund for Masters in Affiliated Hospital of Zunyi Medical University(No.2016-43)。
AIM:To report on the clinical features of patients with retinal amyloid angiopathy(RAA)who were identified to be caused by the transthyretin(TTR)Gly83Arg variant.METHODS:Case series of five patients diagnosed with RAA...