GENIPOSIDE

作品数:45被引量:224H指数:10
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相关领域:医药卫生更多>>
相关作者:杨阳陈万生孙连娜李芳张海燕更多>>
相关机构:南方医科大学第二军医大学成都中医药大学江西中医药大学更多>>
相关期刊:《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》《Journal of Geriatric Cardiology》《Journal of Traditional Chinese Medicine》《Synthetic and Systems Biotechnology》更多>>
相关基金:国家自然科学基金国家重点基础研究发展计划广东省自然科学基金湖北省自然科学基金更多>>
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Effect of L-theanine combined with geniposide on depression-like behavior induced by the chronic unpredictable mild stress(CUMS)in mice
《Food Science and Human Wellness》2025年第4期1424-1440,共17页Qiming Yu Yan Zhu Tao Jiang Ying Gao Nan Ling Na Wang John Shi Weichun Pan Qizhen Du Junfeng Yin 
funded by Innovation Project for Chinese Academy of Agricultural Sciences(CAAS-ASTIP-TRI);China Agriculture Research System of MOF and MARA(CARS-19)。
Depression is a prevalent mental disorder with limited effective treatments,posing a significant global issue.This study explored L-theanine and geniposide,key components in“food-medicine homology”materials,to deter...
关键词:CUMS DEPRESSION L-THEANINE GENIPOSIDE TRANSTHYRETIN 
Geniposide alleviates heart failure with preserved ejection fraction in mice by regulating cardiac oxidative stress via MMP2/SIRT1/GSK3βpathway
《Acta Pharmacologica Sinica》2024年第12期2567-2578,共12页Yan-lu Han Teng-teng Yan Hua-xin Li Sha-sha Chen Zhen-zhen Zhang Meng-yao Wang Mei-jie Chen Yuan-li Chen Xiao-xiao Yang Ling-ling Wei Ya-jun Duan Shuang Zhang 
supported by the National Natural Science Foundation of China(NSFC)Grant 82304503 to Shuang Zhang;Anhui Provincial Natural Science Foundation Grant 2308085QH305 to Shuang Zhang;the Fundamental Research Funds for the Central Universities(Hefei University of Technology)grant JZ2023HGTB0288 to Shuang Zhang。
Heart failure with preserved ejection fraction(HFpEF)is a complex clinical syndrome with cardiac dysfunction,fluid retention and reduced exercise tolerance as the main manifestations.Current treatment of HFpEF is usin...
关键词:HFpEF GENIPOSIDE SIRT1 MMP2 GSK3Β oxidative stress 
Mechanism of Geniposide on non-alcoholic steatohepatitis rats based on protein ubiquitination
《China Medical Abstracts(Internal Medicine)》2024年第3期141-141,共1页LIANG Huiqing 
Objective To observe the effect of Geniposide on non-alcoholic steatohepatitis (NASH) rats,and to explore its mechanism based on protein ubiquitination.Methods NASH rat model was established by high-fat diet for 16 we...
关键词:RATS UBIQUITIN HEPATITIS 
Determination of Chlorogenic Acid,Geniposide,Total Flavonoids and Total Triterpenes in Wulan-13
《Medicinal Plant》2024年第2期6-9,共4页Xiaohua WU Burenbatu 
Supported by National Natural Science Foundation of China(82274210).
[Objectives]This study was conducted to establish a method for the determination of chlorogenic acid,geniposide,total flavonoids and total triterpenes in Wulan-13.[Methods]The contents of chlorogenic acid and geniposi...
关键词:Wulan-13 HPLC Ultraviolet spectrophotometer Content determination 
Investigation of paeonol-geniposide on acute alcoholic liver injury based on uniform design method
《Journal of Hainan Medical University》2022年第24期25-31,共7页LIU Ke LIU Yu-long SUN Min LIU Ling-ling ZHANG Lu-ning YAN Gui-ming 
Anhui Natural Science Foundation(No.2008085MH300)。
Objective:To explore the optimal ratio and compatibility effect of paeonol-geniposide combination on acute alcoholic liver injury by uniform design.Methods:Lieber-DeCarli alcoholic liquid feed was used to induce acute...
关键词:PAEONOL GENIPOSIDE Alcoholic liver injury Uniform design Chinese medicine effective ingredient ratio 
Genipin and geniposide from Gardenia jasminoides:An overview of their anti-cancer and other pharmacological properties
《Journal of Chinese Pharmaceutical Sciences》2022年第1期1-12,共12页Eric Wei Chiang Chan Siu Kuin Wong Hung Tuck Chan 
Genipin and geniposide are iridoids from the fruits of Gardenia jasminoides.Both compounds have a methyl acetate(-COOCH_(3))group at C4 and a hydroxyl(-OH)group at C10.As an iridoid glucoside with a glucose moiety at ...
关键词:IRIDOID Iridoid glucoside ANTI-CANCER CYTOTOXICITY 
Expression of heat-resistant β-glucosidase in Escherichia coli and its application in the production of gardenia blue被引量:2
《Synthetic and Systems Biotechnology》2021年第3期216-223,共8页Wenxi Li Jielin Li Ying Xu Yan Huang Shuqi Xu Zirui Ou Xiaoli Long Xinyu Li Xinyu Liu Zening Xiao Jiaqi Huang Weizhao Chen 
funded by Guangdong Provincial Undergraduate Training Program for Innovation and Entrepreneurship(grant No.202110590065);the Undergraduate Academic Competition Project of Shenzhen University(grant No.803-0000290846).
Gardenia blue is a natural blue pigment that is environmentally friendly,non-toxic,and stable.The hydrolysis of geniposide,catalyzed byβ-glucosidase,is a critical step in the production process of gardenia blue.Howev...
关键词:Β-GLUCOSIDASE Gardenia blue GENIPOSIDE Orthogonal experiment 
Combination of Geniposide and Eleutheroside B Exerts Antidepressant-like Effect on Lipopolysaccharide-Induced Depression Mice Model被引量:6
《Chinese Journal of Integrative Medicine》2021年第7期534-541,共8页ZHANG Bo CHANG Hong-sheng HU Kai-li YU Xue LI Li-na XU Xiang-qing 
Supported by the Shandong Key Research and Development Plan(No.2017GSF19112)。
Objective To study the antidepressant-like effect and action mechanism of geniposide and eleutheroside B combination treatment on the lipopolysaccharide(LPS)-induced depression mice model.Methods Depression mice model...
关键词:GENIPOSIDE eleutheroside B antidepressant effect mechanism 5-HYDROXYTRYPTAMINE GLUTAMATE 
Idiopathic mesenteric phlebosclerosis associated with long-term oral intake of geniposide被引量:5
《World Journal of Gastroenterology》2021年第22期3097-3108,共12页Yang Wen You-Wei Chen Ai-Hong Meng Ming Zhao Song-Hua Fang Yan-Qing Ma 
Supported by the Fund of Medical and Health Research Projects of Health Commission of Zhejiang Province,No.2018KY247 and No.2019KY035.
BACKGROUND Idiopathic mesenteric phlebosclerosis(IMP)is a rare disease,and its etiology and risk factors remain uncertain.AIM To investigate the possible influence of Chinese herbal liquid containing geniposide on IMP...
关键词:Idiopathic mesenteric phlebosclerosis Phlebosclerotic colitis Chinese herbal liquid GENIPOSIDE COLONOSCOPY Computed tomography 
Geniposide improves insulin resistance through AMPK-mediated Txnip protein degradation in 3T3-L1 adipocytes被引量:8
《Acta Biochimica et Biophysica Sinica》2021年第2期160-169,共10页Wanjun Zhao Mengru Pu Shenli Shen Fei Yin 
This work was supported by the grants from Chongqing Science and Technology Committee(No.2017jcyjBX0077);the Innovative Research Team Development Program at the University of Chongqing(No.CXTDX201601031).
Thioredoxin-interacting protein(Txnip)has emerged as a key regulator of insulin resistance.In this study,we investigated the roles of geniposide and Txnip in insulin resistance in differentiated 3T3-L1 adipocytes.Our ...
关键词:adenosine monophosphate-activated protein kinase(AMPK) GENIPOSIDE insulin resistance protein degradation thioredoxin-interacting protein(Txnip) 
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