云南高校图书馆联盟文献共享服务平台- CYTOTOXICITY

CYTOTOXICITY: 作品数：857被引量：1999H指数：16; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：黄利华黄东谷永红甘丽阎雪彬更多>>; 相关机构：北京大学中国科学院沈阳药科大学中南大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划中国博士后科学基金更多>>

ERLNs augment simultaneous delivery of GFSV into PC-3 cells:Influence of drug combination on SDH,GPX-4,5α-RD,and cytotoxicity: 《Oncology Research》2025年第4期919-935,共17页RIYAD F.ALZHRANI LAMA BINOBAID ABDULAZIZ A.ALORAINI MESHAL S.ALSAHLI AHMED H.BAKHEIT HANADI H.ASIRI SABRY M.ATTIA ALI ALHOSHANI GAMALELDIN I.HARISA; Objective:Prostate cancer(PCA)is the second most widespread cancer among men globally,with a rising mortality rate.Enzyme-responsive lipid nanoparticles(ERLNs)are promising vectors for the selective delivery of antica...; 关键词：Prostate cancer(PCA) Nanoparticle biocompatibility Molecular docking simulation(MDS) Apoptosis Drug repurposing

Critical new insights into the interactions of hexafluoropropylene oxide-dimer acid(GenX or HFPO-DA)with albumin at molecular and cellular levels: 《Journal of Environmental Sciences》2025年第3期88-98,共11页Shi-Ya Peng Ya-Di Yang Rong Tian Naihao Lu; supported by the National Natural Science Foundation of China(Nos.31960196,31760255,and 82260637);Jiangxi Provincial Natural Science Foundation(No.20212BAB205016).; A key characteristic to be elucidated,to address the harmful health risks of environmental perfluorinated alkyl substances(PFAS),is their binding modes to serum albumin,the most abundant protein in blood.Hexafluoropro...; 关键词：GenX Protein binding ALBUMIN CYTOTOXICITY Risk assessment

Cytotoxicity and Hepatic Effects in Vivo of the Phytomedicinal Antipalu Used by the Population of Abidjan: 《American Journal of Molecular Biology》2025年第1期25-38,共14页Kouakou Serge Kouassi Aka Edwige Ayebe Irié Lou Bohila Emilie Kamo Djenabou Kamagate Ouagnonan Ismael Soro Gnogbo Alexis Bahi Allico Joseph Djaman; Antipalu is a phytomedicinal medicinal beverage that is popular in the District of Abidjan, particularly for the treatment of malaria. However, Antipalu could present potential health effects on patients, and few toxi...; 关键词：Phytomedicinal Antipalu CYTOTOXICITY Vero Cells Hepatic Biomarkers

The ABC transporter SmABCG1 mediates tanshinones export from the peridermic cells of Salvia miltiorrhiza root: 《Journal of Integrative Plant Biology》2025年第1期135-149,共15页Yajing Li Junfeng Chen Jingyu Zhi Doudou Huang Yuchen Zhang Lei Zhang Xinyi Duan Pan Zhang Shi Qiu Jiaran Geng Jingxian Feng Ke Zhang Xu Yang Shouhong Gao Wenwen Xia Zheng Zhou Yuqi Qiao Bo Li Qing Li Tingzhao Li Wansheng Chen Ying Xiao; financially supported by the National Key Research and Development Program of China(2022YFC3501700);the National Natural Science Foundation of China(82304662,82374159,32070327,32170402);the National Key Research and Development Program of China(2023YFC3504800);Chenguang project of Shanghai(23CGA52);Science and Technology Development Program of Shanghai University of Traditional Chinese Medicine(23KFL051);Shanghai Municipal Science and Technology Commission(23XD1423500)。; Plants have mechanisms to transport secondary metabolites from where they are biosynthesized to the sites where they function,or to sites such as the vacuole for detoxification.However,current research has mainly focu...; 关键词：ATP-binding cassette transporter biosynthesis gene cluster CYTOTOXICITY EXPORT peridermic cells TANSHINONE

Analyzing the Cytotoxic and Genetic Impact of Datura stramonium Extract on MCF7 and HT29 Cancer Cells:A Metabolite and Gene Expression Study: 《Phyton-International Journal of Experimental Botany》2025年第1期181-198,共18页Fayez Althobaiti Hadeer Darwish Raghad Alruqayb Saqer S.Alotaibi Fahad E.Alharthi Ibrahim Jafri Sarah Awwadh Altalhi Ghadi Alsharif Hussam Awwadh E Althagafi Hesham Noureldeen Sarah Alharthi Jawaher Albaqami Najla Amin T.Al Kashgry Ahmed Noureldeen; Taif University,Saudi Arabia,Project No.(TU-DSPP-2024-74).; The interest in using the Datura stramonium plant is due to its natural products,which are used in many pharmaceutical industries.The objective of the current study was to assess the therapeutic and cytotoxic effects ...; 关键词：Datura stramonium secondary metabolites GC-MS analysis CYTOTOXICITY breast and colon cancer cell lines MTT assay

Fabrication and comprehensive evaluation of Zr-based bulk metallic glass matrix composites for biomedical applications: 《Science China Materials》2024年第12期4087-4100,共14页Mariusz Hasiak Beata Sobieszczańska Amadeusz Łaszcz Michał Biały Jacek Chęcmanowski Tomasz Zatoński; Open Access funding provided by Wrocław University of Science and Technology; The aim of this study is to fabricate Zr-based bulk metallic glass matrix composites(BMG-MCs)for biomedical usage and subject them to a comprehensive and farreaching analysis with respect to their mechanical propertie...; 关键词：metallic glasses COMPOSITES BIOMATERIALS mechanical property CYTOTOXICITY

Antibacterial and cytotoxicity activity of green synthesized silver nanoparticles using aqueous extract of naartjie(Citrus unshiu)fruit peels: 《Emerging Contaminants》2024年第4期153-163,共11页Livhuwani Mafhala Nomcebo Khumalo Nkosingiphile Excellent Zikalala Shohreh Azizi Karen Jacqueline Cloete Garland Kgosi More Ilunga Alain Kamika Touhami Mokrani Ali Akbar Zinatizadeh Malik Maaza; funding from South African Coal,Oil,and Gas Corporation-National Research Foundation(SASOL-NRF)Uni-versity Collaborative Research Grants(Grant No.138626).; The application of plant extracts in the green synthesis of silver nanoparticles(AgNPs)has attracted significant attention owing to their eco-friendliness and cost-effective features.However,nanoparticles synthesized ...; 关键词：Antimicrobial activity Citrus unshiu Cytotoxicity activity Green synthesis Silver nanoparticle

Modulating the Oxidation Degree of Linear Polyethyleneimine for Preparation of Highly Efficient and Low-cytotoxicity Degradable Gene Delivery Carriers: 《Chinese Journal of Polymer Science》2024年第11期1699-1709,I0008,共12页Xiao-Ya Guo Zhi-Yu Yang Hua-Pan Fang Dan-Hua Zhou Xuan Pang Hua-Yu Tian Xue-Si Chen; financially supported by National Key Research and Development Program of China(No.2021YFB3800900);the National Natural Science Foundation of China(Nos.51925305,51833010 and 52203183);Natural Science Foundation of Xiamen,China(No.3502Z202371004);Fundamental Research Funds for the Central Universities(No.20720230004);the talent cultivation project Funds for the Innovation Laboratory for Sciences and Technologies of Energy Materials of Fujian Province(No.HRTP-[2022]52)。; Polyethyleneimine(PEI),as a widely used polymer material in the field of gene delivery,has been extensively studied for modification and shielding to reduce its cytotoxicity.However,research aimed at preparing degrada...; 关键词：POLYETHYLENEIMINE Gene delivery Gene transfection Degradable gene carriers

Highly oxidized sesquiterpenoids from Parasenecio rubescens and assessment of their cytotoxicity: 《Chinese Journal of Natural Medicines》2024年第11期1020-1029,共10页JIN An DUAN Fangfang RUAN Hanli; supported by the National Natural Science Foundation of China(Nos.22077041,81803847 and 31770380).; A phytochemical investigation of the whole plant of Parasenecio rubescens(S.Moore)Y.L.Chen yielded 14 previ-ously undescribed,highly oxidized bisabolane-type sesquiterpenoids,named pararunines L-Y,along with one known...; 关键词：Parasenecio rubescens Asteraceae Bisabolane-type sesquiterpenoids Oplopane-type sesquiterpenoid Cytotoxic activity

Unveiling the cytotoxicity of a new gold(I)complex towards hepatocellular carcinoma by inhibiting TrxR activity: 《Acta Biochimica et Biophysica Sinica》2024年第10期1537-1548,共12页Yuan Wang Haokun Yuan Ruiqin Fang Ran Zhang Wei-jia Wang; supported by the grants from the National Natural Science Foundation of China(No.82072727);the Department of Science and Technology of Sichuan Province(Nos.2021ZYD0092 and 2022NSFSC0721).; Hepatocellular carcinoma(HCC),the predominant type of liver cancer,is an aggressive malignancy with limited therapeutic options.In this study,we assess a collection of newly designed gold(I)phosphine complexes.Remarka...; 关键词：gold complex hepatocellular carcinoma NECROPTOSIS thioredoxin reductase reactive oxygen species

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