supported by the Sichuan Science and Technology Program,No.2023YFS0164(to JC);the National Natural Science Foundation of China,No.82401629(to XL);the Natural Science Foundation of Sichuan Province,No.2024NSFSC1646(to XL);the China Postdoctoral Science Foundation,Nos.GZC20231811(to XL)and 2024T170601(to XL)。
Enhancing neurological recovery and improving the prognosis of spinal cord injury have gained research attention recently.Spinal cord injury is associated with a complex molecular and cellular microenvironment.This co...
supported by the Natio`nal Natural Science Foundation of China,No. 81801241;a grant from Sichuan Science and Technology Program,No. 2023NSFSC1578;Scientific Research Projects of Southwest Medical University,No. 2022ZD002 (all to JX)。
Neuronal growth, extension, branching, and formation of neural networks are markedly influenced by the extracellular matrix—a complex network composed of proteins and carbohydrates secreted by cells. In addition to p...
Tissue engineering and regenera-tive medicine have shown signifi-cant potential for repairing and regenerating damaged tissues and can be used to provide personalized treatment plans,with broad applica-tion prospects....
supported by the National Natural Science Foundation of China(81925027,82002275,and 32271421);the Priority Academic Program Development of Jiangsu Higher Education Institutions.
Bone injuries induced by accidents or bone-related disease have dramatically increased in the past decades.The application of biomaterials has become an inextricable part of treatment for new bone formation and regene...
supported by the Areas of Excellence Scheme(AoE/M402/20);the Knowledge Transfer Project Fund(KPF24GWP05);the IdeaBooster Fund(IDBF24MED12);the HKSTP Ideation Fund(Ideation 23-0698);the ITC Technology Startup Support Scheme for Universities(TSU24MED05).
Anterior cruciate ligament(ACL)injuries are frequently caused by sports injuries and trauma.In cases involving complete tears,ACL reconstruction(ACLR)surgery is the only way to restore the ligament’s integrity.When s...
Supported by Henan Province Key Research and Development Program,No.231111311000;Henan Provincial Science and Technology Research Project,No.232102310411;Henan Province Medical Science and Technology Key Project,No.LHGJ20220566 and No.LHGJ20240365;Henan Province Medical Education Research Project,No.WJLX2023079;Zhengzhou Medical and Health Technology Innovation Guidance Program,No.2024YLZDJH022.
Necrotizing fasciitis(NF)is a rapidly progressing,life-threatening soft tissue infection,with upper limb NF posing a particularly serious threat to patient survival and quality of life.Negative pressure wound therapy(...
supported by the National Natural Science Foundation of China(Grant No.52473121,52403370 and 52221006);Fundamental Research Funds for the Central Universities(buctrc202020,buctrc202312).
The intricate hierarchical structure of musculoskeletal tissues,including bone and interface tissues,necessitates the use of complex scaffold designs and material structures to serve as tissue-engineered substitutes.T...
National Natural Science Foundation of China(82230071,82172098);Integrated Project of Major Research Plan of National Natural Science Foundation of China(92249303);Shanghai Committee of Science and Technology(23141900600,Laboratory Animal Research Project);Shanghai Clinical Research Plan of SHDC2023CRT01;Young Elite Scientist Sponsorship Program by China Association for Science and Technology(YESS20230049)。
Accumulating research has shed light on the significance of skeletal interoception,in maintaining physiological and metabolic homeostasis related to bone health.This review provides a comprehensive analysis of how ske...
support of the National Natural Science Foundation of China(Grant No.52205593);Shaanxi Natural Science Foundation Project(2024JC-YBMS-711).
The incidence of large bone defects caused by traumatic injury is increasing worldwide,and the tissue regeneration process requires a long recovery time due to limited self-healing capability.Endogenous bioelectrical ...
supported by the Innovative Research Group Project of the National Natural Science Foundation of China(T2121004);Key Programme(52235007);National Outstanding Youth Foundation of China(52325504).
Hydrogel scaffolds have numerous potential applications in the tissue engineering field.However,tough hydrogel scaffolds implanted in vivo are seldom reported because it is difficult to balance biocompatibility and hi...