NEUROREGENERATION

作品数：371被引量：1577H指数：18
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相关领域：医药卫生生物学更多>>
相关机构：大连医科大学重庆医科大学更多>>
相关期刊：《Bioactive Materials》《Military Medical Research》《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》《Neuroimmunology and Neuroinflammation》更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划广东省自然科学基金北京市自然科学基金更多>>
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Enhanced neurogenesis after ischemic stroke:The interplay between endogenous and exogenous stem cells
《Neural Regeneration Research》2026年第1期212-223,共12页Ruxu Geng Yuhe Wang Renzhi Wang Jun Wu Xinjie Bao 
supported by the National Key Research and Development Program of China,No.2018YFA0108602;the CAMS Initiative for Innovative Medicine,No.2021-1-I2M-019;National High-Level Hospital Clinical Research Funding,No.2022-PUMCH-C-042(all to XB)。
Ischemic stroke is a significant global health crisis,frequently resulting in disability or death,with limited therapeutic interventions available.Although various intrinsic reparative processes are initiated within t...
关键词：brain-derived neurotrophic factor endogenous neuroregeneration exosomes hydrogels ischemic stroke mesenchymal stem cells neural stem cells NEUROGENESIS stem cell transplantation 
Stiffness-tunable biomaterials provide a good extracellular matrix environment for axon growth and regeneration
《Neural Regeneration Research》2025年第5期1364-1376,共13页Ronglin Han Lanxin Luo Caiyan Wei Yaru Qiao Jiming Xie Xianchao Pan Juan Xing 
supported by the Natio`nal Natural Science Foundation of China,No. 81801241;a grant from Sichuan Science and Technology Program,No. 2023NSFSC1578;Scientific Research Projects of Southwest Medical University,No. 2022ZD002 (all to JX)。
Neuronal growth, extension, branching, and formation of neural networks are markedly influenced by the extracellular matrix—a complex network composed of proteins and carbohydrates secreted by cells. In addition to p...
关键词：ALGINATE axon growth BIOMATERIALS extracellular matrix neural repair neurons NEUROREGENERATION POLYACRYLAMIDE POLYDIMETHYLSILOXANE stiffness 
Krüppel-like factor 2(KLF2),a potential target for neuroregeneration
《Neural Regeneration Research》2024年第11期2327-2328,共2页Surajit Hansda Prateeksha Prateeksha Hiranmoy Das 
supported in part by National Institutes of Health grants,R01AR068279(NIAMS),STTR R42EY031196(NEI),and STTR 1R41AG057242(NIA)(to HD).
Neurological disorders and injuries lead to the impairment or depletion of neurons in terms of quantity,structure,or function,resulting in the loss of cognitive,emotional,and physical abilities in human beings.This,in...
关键词：COMPANIES INJURIES POTENTIAL 
From the dust:extracellular vesicles as regulators of development and neuroregeneration
《Neural Regeneration Research》2024年第5期933-934,共2页Leon G.Coleman Jr 
National Institute on Alcohol Abuse and Alcoholism AA024829,AA028924,AA028599 and the Bowles Center for Alcohol Studies(to LGCJ).
First impressions can have a lasting impact.In science,this can be especially problematic,because our lack of understanding often causes us to mislabel and thus ignore important biological processes.In this vein,extra...
关键词：FIGURE EXTRACELLULAR 
Multiple sclerosis drug repurposing for neuroregeneration
《Neural Regeneration Research》2024年第3期507-508,共2页Peter Göttle Michael Dietrich Patrick Küry 
financially supported by Novartis (to PK)
Multiple sclerosis(MS)is an autoimmune disorder of the central nervous system(CNS)and is primarily characterized by immune cell infiltration leading to relapses followed by remission phases and a disease course turnin...
关键词：DRUGS IMPAIRED IRREVERSIBLE 
Interplay between mesenchymal stromal cells and the immune system after transplantation: implications for advanced cell therapy in the retina被引量：1
《Neural Regeneration Research》2024年第3期542-547,共6页María Norte-Muñoz David García-Bernal Diego García-Ayuso Manuel Vidal-Sanz Marta Agudo-Barriuso 
funded by the Spanish Ministry of Economy and Competitiveness,No.PID(2019)-106498GB-100 (to MVS);by the Instituto de Salud CarlosⅢ,Fondo Europeo de Desarrollo Regional"Una manera de hacer Europa",No.PI19/00071 (to MAB);the RETICS subprograms of Spanish Networks OftoRed,Nos.RD16/0008/0026 (to DGB) and RD16/0008/0016 (to DGB);RICORS Terav,No.RD16/0011/0001 (to DGB)from Instituto de Salud CarlosⅢ;by the Fundacion Seneca,Agencia de Cienciay Tecnologia Región de Murcia,No.19881/GERM/15 (all to MVS)
Advanced mesenchymal stromal cell-based therapies for neurodegenerative diseases are widely investigated in preclinical models.Mesenchymal stromal cells are well positioned as therapeutics because they address the und...
关键词：adaptive immunity cell therapy central nervous system immune system innate immunity mesenchymal stromal cells NEUROREGENERATION preclinical studies RETINA TRANSPLANTATION 
Annexin A1 in the nervous and ocular systems
《Neural Regeneration Research》2024年第3期591-597,共7页Aijia Wang Hong Zhang Xing Li Yin Zhao 
supported by the National Natural Science Foundation of China,Nos.31800868(to YZ),32271037(to XL)and 82271090(to HZ).
The therapeutic potential of Annexin A1,an important member of the Annexin superfamily,has become evident in results of experiments with multiple human systems and animal models.The anti-inflammatory and pro-resolving...
关键词：Annexin A1(ANXA1) GLAUCOMA nervous system NEUROPROTECTION NEUROREGENERATION ocular disease RETINA 
Skin derived precursors induced Schwann cells mediated tissue engineering-aided neuroregeneration across sciatic nerve defect被引量：1
《Bioactive Materials》2024年第3期572-590,共19页Chengbin Xue Hui Zhu Hongkui Wang Yaxian Wang Xi Xu Songlin Zhou Dong Liu Yahong Zhao Tianmei Qian Qi Guo Jin He Kairong Zhang Yun Gu Leilei Gong Jian Yang Sheng Yi Bin Yu Yongjun Wang Yan Liu Yumin Yang Fei Ding Xiaosong Gu 
supported by National Natural Science Foundation of China(Grant No.31730031,82172104,81873767);National Key Research and Development Program of China(2017YFA0104703);Jiangsu Provincial Key Medical Center,Jiangsu Provincial Medical Innovation Center(CXZX202212);Jiangsu Provincial Medical Key Discipline(ZDXK202240);the Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD);Technology Project of Nantong(MS22022008).
A central question in neural tissue engineering is how the tissue-engineered nerve(TEN)translates detailed transcriptional signals associated with peripheral nerve regeneration into meaningful biological processes.Her...
关键词：SKP-SCs-TEN Transcriptomic feature Reconstruction of regenerative MICROENVIRONMENT Molecular regulation Molecular regenerative-medicine 
Bioactive superparamagnetic iron oxide-gold nanoparticles regulated by a dynamic magnetic field induce neuronal Ca^(2+)influx and differentiation被引量：5
《Bioactive Materials》2023年第8期478-489,共12页Elias Georgas Muzhaozi Yuan Jingfan Chen Ya Wang Yi-Xian Qin 
funded by the United States National Science Foundation(NSF)(CAREER Award#CMMI 1851635,Y.W.and GCR awards#ECCS 2021081(Y.W.);#ECCS 2020867(Y-X.Q).
Treating neurodegenerative diseases,e.g.,Alzheimer’s Disease,remains a significant challenge due to the limited neuroregeneration rate in the brain.The objective of this study is to evaluate the hypothesis that exter...
关键词：Calcium influx Membrane potential Dynamic magnetic fields NEUROREGENERATION SPIO-Au Core-shell nanoparticles 
Novel therapeutic strategies targeting mitochondria as a gateway in neurodegeneration被引量：6
《Neural Regeneration Research》2023年第5期991-995,共5页Diogo Trigo Jose Joao Vitoria Odete A.B.da Cruz e Silva 
supported by a grant from the Fundacao para a Ciencia e Tecnologia of the Ministerio da Educacao e Ciencia (2020.02006.CEECIND);iBiMED,University of Aveiro and the Fundacao para a Ciência e Tecnologia of the Ministerio da Educacao e Ciencia (to DT)。
In recent years, multiple disciplines have focused on mitochondrial biology and contributed to understanding its relevance towards adult-onset neurodegenerative disorders. These are complex dynamic organelles that hav...
关键词：Alzheimer’s disease AXON energy homeostasis glymphatic system MITOCHONDRIA mitostasis NEURODEGENERATION NEUROREGENERATION Parkinson’s disease therapeutical strategies 
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