With the advances in medicine and technology,life expectancy has increased significantly in recent decades.While this is positive news,it also brings major challenges to public health systems.As people live longer,the...
supported by the National Natural Science Foundation of China,Nos.81970820(to HX),31771644(to JL),31930068(to JL),82371176(to JL),81801331(to LC);National Key Research and Development Project of China.Nos.2017YFA0104100(to JL),2017YFA0701304(to HX);Shanghai Yangzhi Rehabilitation Hospital(Shanghai Sunshine Rehabilitation Center)Talent Introduction Plan,No.KYPT202204(to LC);the Fundamental Research Funds for the Central Universities,No.22120230292(to JL)。
Inflammation plays a crucial role in the regeneration of fish and avian retinas.However,how inflammation regulates Müller glia(MG)reprogramming remains unclear.Here,we used single-cell RNA sequencing to investigate t...
Photobiomodulation has been known to have potential medicinal effects for ages.It involves the use of specific wavelengths to target specific regions in the cell.Different health conditions have been reported to be tr...
supported by National Science Center(Narodowe Centrum Nauki)grant No.UMO-2019/33/B/NZ4/00587 to TB.
The retina plays a fundamental role in the process of vision,serving as the primary interface between external visual stimuli and the central nervous system.Because the retina is exposed to a variety of environmental ...
supported by Natural Science Foundation of Zhejiang Province(LY24C100002);Wenzhou Science and Technology Foundation(Y20210266);Engineering Research Center of Clinical Functional Materials and Diagnosis&Treatment Devices of Zhejiang Province(WIUCASK20004);Zhejiang Engineering Research Center for Tissue Repair Materials(WIUCASZZXF21002);Joint Medical Research Center of Xiangshan Hospital Affiliated to Wenzhou Medical University and Wenzhou Institute of Chinese Academy of Sciences(WIUCAS)(XSZX09);startup grant from WIUCAS(WIUCASQD2023022,WIUCASQD2022035).
Currently,generalized therapy for traumatic optic neuropathy(TON)is lacking.Various strategies have been developed to protect and regenerate retinal ganglion cells(RGCs)after TON.Intravitreal injection of supplements ...
Supported by the Tianjin Health Research Project(No.ZC20069;No.TJWJ2022MS040);the Foundation of the Committee of Integrated Traditional Chinese and Western Medicine(No.2021011);the Science and Technology Foundation of Tianjin Eye Hospital(No.YKYB1901).
AIM:To explore the effect and mechanism of Lycium barbarum polysaccharide(LBP)inhibiting retinal neovascularization.METHODS:In vitro tests were performed on human retinal microvascular endothelial cells(HRECs)from thr...
AIM:To examine the subclinical alterations in the retina and choroid between patients with 2019 coronavirus disease(COVID-19)-related lung involvement and the healthy control group.METHODS:In this prospective case-con...
supported by the State Key Laboratory of Ophthalmology,Zhongshan Ophthalmic Center,Sun Yat-Sen University,Guangzhou,China;the National Key R&D Program of China(2023YFC2506100 to X.L.);the National Natural Science Foundation of China(82150710555 and 82220108016 to X.L.);the Natural Science Foundation of Guangdong Province grant(2021A1515010684 to W.L.);the Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science(2020B1212060033 to W.L.),and the Guangzhou Basic Research Program(2023A03J0182 to W.L.).
The retinal pigment epithelium(RPE)between retinal photoreceptors and choroidal capillaries is a single layer of cells that are of critical importance to the eye.RPE cells are derived from the anterior neural plate of...
National Key Research and Development Program of China(Grant No.2021YFA1101203).
In zebrafish,Müller glia(MG)cells retain the ability to proliferate and de-differentiate into retinal progenitor-like cells,subsequently differentiating into retinal neurons that can replace those damaged or lost due...