REGENERATION

作品数：1613被引量：4728H指数：24
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Single-cell RNA sequencing reveals the heterogeneity and interactions of immune cells and Müller glia during zebrafish retina regeneration
《Neural Regeneration Research》2025年第12期3635-3648,共14页Hui Xu Lining Cao Yuxi Chen Cuiping Zhou Jie Xu Zhuolin Zhang Xiangyu Li Lihua Liu Jianfeng Lu 
supported by the National Natural Science Foundation of China,Nos.81970820(to HX),31771644(to JL),31930068(to JL),82371176(to JL),81801331(to LC);National Key Research and Development Project of China.Nos.2017YFA0104100(to JL),2017YFA0701304(to HX);Shanghai Yangzhi Rehabilitation Hospital(Shanghai Sunshine Rehabilitation Center)Talent Introduction Plan,No.KYPT202204(to LC);the Fundamental Research Funds for the Central Universities,No.22120230292(to JL)。
Inflammation plays a crucial role in the regeneration of fish and avian retinas.However,how inflammation regulates Müller glia(MG)reprogramming remains unclear.Here,we used single-cell RNA sequencing to investigate t...
关键词：immune cells inflammation Jak1-Stat3 signaling microglia Müller glia REGENERATION reprogramming RETINA single-cell RNAseq ZEBRAFISH 
Human induced pluripotent stem cell-derived therapies for regeneration after central nervous system injury
《Neural Regeneration Research》2025年第11期3063-3075,共13页Stephen Vidman Yee Hang Ethan Ma Nolan Fullenkamp Giles W.Plant 
supported by Ohio State Start Up Fund;National Institutes of Health(NIH);Department of Defense(DoD);Wings for Life Spinal Cord Research Foundation,Wings for Life Spinal Cord Research Foundation(Austria);California Institute of Regenerative Medicine(CIRM);International Spinal Research Trust(United Kingdom);Stanford University Bio-X Program Interdisciplinary Initiatives Seed Grant IIP-7;Dennis Chan Foundation;Klein Family Fund;Lucile Packard Foundation for Children's Health;Stanford Institute for Neuro-Innovation and Translational Neurosciences(SINTN);Saunders Family Neuroscience Fund;James Doty Neurosurgery Fund;Hearst Neuroscience Fund;Eileen Bond Research Fund(to GP)。
In recent years,the progression of stem cell therapies has shown great promise in advancing the nascent field of regenerative medicine.Considering the non-regenerative nature of the mature central nervous system,the c...
关键词：axon regeneration central nervous system regeneration induced pluripotent stem cells NEUROTRAUMA regenerative medicine spinal cord injury stem cell therapy 
Retraction:The effects of exercise interventions on brain-derived neurotrophic factor levels in children and adolescents:a meta-analysis
《Neural Regeneration Research》2025年第11期3075-3075,共1页
At the request of the authors,Neural Regeneration Research is retracting the research article titled"The effects of exercise interventions on brain-derived neurotrophic factor levels in children and adolescents:a meta...
关键词：SYNTHESIS FIGURE REGENERATION 
Crosstalk between androgen signaling and the chemokine receptor CXCR4:a novel strategy to promote myelin regeneration
《Neural Regeneration Research》2025年第9期2581-2582,共2页Marianne Bardy-Lagarde Narimène Asbelaoui Abdel Mouman Ghoumari 
supported by a grant from the French Multiple Sclerosis Society(ARSEP,Grant Number:R20163LL)(to AMG)。
Multiple sclerosis(MS)is the most common chronic disease of the central nervous system(CNS)in young adults and represents the first cause of severe handicap,originally non-traumatic(Oh et al.,2018).MS is chara cterize...
关键词：MYELIN CXCR4 
Neurocircuit regeneration by extracellular matrix reprogramming
《Neural Regeneration Research》2025年第8期2300-2301,共2页Shengzhang Su Ian N.Levasseur Kimberly M.Alonge 
supported by National Institute on Aging(NIH-NIA)R21 AG074152(to KMA);National Institute of Allergy and Infectious Diseases(NIAID)grant DP2 AI171150(to KMA);Department of Defense(DoD)grant AZ210089(to KMA)。
The brain's extracellular matrix(ECM),which is comprised of protein and glycosaminoglycan(GAG)scaffolds,constitutes 20%-40% of the human brain and is considered one of the largest influencers on brain cell functioning...
关键词：MATRIX PROGRAMMING 
Mechanism by which Rab5 promotes regeneration and functional recovery of zebrafish Mauthner axons
《Neural Regeneration Research》2025年第6期1816-1824,共9页Jiantao Cui Yueru Shen Zheng Song Dinggang Fan Bing Hu 
supported by the Research Funds of the Center for Advanced Interdisciplinary Science and Biomedicine of IHM,No.QYZD20220002;the National Natural Science Foundation of China,No.82071357;a grant from the Ministry of Science and Technology of China,No.2019YFA0405600 (all to BH)。
Rab5 is a GTPase protein that is involved in intracellular membrane trafficking. It functions by binding to various effector proteins and regulating cellular responses, including the formation of transport vesicles an...
关键词：axonal regeneration Mauthner cell nerve regeneration Rab5 ZEBRAFISH 
Combinatorial therapies for spinal cord injury repair
《Neural Regeneration Research》2025年第5期1293-1308,共16页Carla S.Sousa Andreia Monteiro António J.Salgado Nuno A.Silva 
funded by National funds,through the Foundation for Science and Technology (FCT)-project UIDB/50026/2020 (DOI 10.54499/UIDB/50026/2020),UIDP/50026/2020 (DOI 10.54499/UIDP/50026/2020) and LA/P/0050/2020 (DOI 10.54499/LA/P/0050/2020)(to NAS);Financial support was also provided by Prémios Santa Casa Neurociências–Prize Melo e Castro for Spinal Cord Injury Research (MC-18-2021);Wings for Life Spinal Cord Research Foundation (WFL-PT-14/23)(to NAS)。
Spinal cord injuries have profound detrimental effects on individuals, regardless of whether they are caused by trauma or non-traumatic events. The compromised regeneration of the spinal cord is primarily attributed t...
关键词：electric stimulation neural tissue regeneration NEUROPROTECTION POLYTHERAPY spinal cord injury 
Delaying liver aging:Analysis of structural and functional alterations
《World Journal of Gastroenterology》2025年第15期1-7,共7页Yu-Qin Yao Qiong-Yue Cao Zheng Li 
Supported by the National Natural Science Foundation of China,No.82104525;Open Foundation of Key Laboratory of Tropical Plant Resource Chemistry of Hainan Province,No.rdzw2024s01.
This article is based on a recent bibliometric analysis of research progress on liver aging.The liver is notable for its extraordinary ability to rejuvenate,thereby safeguarding and maintaining the organism’s integri...
关键词：Liver aging TELOMERE HEPATOCYTES Caloric restriction Physical exercise REGENERATION 
Inhibition of HIF-prolyl hydroxylase promotes renal tubule regeneration via the reprogramming of renal proximal tubular cells
《Acta Pharmacologica Sinica》2025年第4期1002-1015,共14页Jing Li Li-ting Chen You-liang Wang Mei-xia Kang Shi-ting Liang Xi-zhen Hong Fan Fan Hou Fu-jian Zhang 
supported by the National Natural Science Foundation of China(82470812 to FJZ);Guangdong Basic and Applied Basic Research Foundation(2024A1515012857 to FJZ);the National Natural Science Foundation of China(Key Program)(82030022 to FFH);the Program of Introducing Talents of Discipline to Universities,111 Plan(D18005 to FFH);the Key Technologies R&D Program of Guangdong Province(2023B1111030004 to FFH);the Guangdong Provincial Clinical Research Center for Kidney Disease(2020B1111170013 to FFH).
The ability of the mammalian kidney to repair or regenerate after acute kidney injury(AKI)is very limited.The maladaptive repair of AKI promotes progression to chronic kidney disease(CKD).Therefore,new strategies to p...
关键词：HYPOXIA prolyl hydroxylase domain inhibitor HIF-1α renal proximal tubular cells chemical reprogramming Sox9+renal progenitor cells renal regeneration 
Novel araucarene diterpenes from Agathis dammara exert hypoglycemic activity by promoting pancreatic β cell regeneration and glucose uptake
《Chinese Journal of Natural Medicines》2025年第4期492-503,共12页Zhewei Yu Yi Zhang Wenhui Wang XinYi Wu Shunzhi Liu Yanlin Bin Hongsheng Li Bangping Cai Zheng Wang Meijuan Fang Rong Qi Mingyu Li Yingkun Qiu 
supported by the Traditional Chinese Medicine Foundation of Xiamen City,China(No.XWZY-2023-0303);the Natural Science Foundation of Xiamen City,China(No.3502Z20227162)。
In this study,araucarene diterpenes,characterized by a pimarene skeleton with a variably oxidized side chain at C-13,were investigated.A total of 16 araucarene diterpenoids and their derivatives were isolated from the...
关键词：Agathis dammara Araucarene DITERPENES HYPOGLYCEMIC Pancreatic β Cells 
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