NEUROTRAUMA

作品数：22被引量：46H指数：4
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Human induced pluripotent stem cell-derived therapies for regeneration after central nervous system injury
《Neural Regeneration Research》2025年第11期3063-3075,共13页Stephen Vidman Yee Hang Ethan Ma Nolan Fullenkamp Giles W.Plant 
supported by Ohio State Start Up Fund;National Institutes of Health(NIH);Department of Defense(DoD);Wings for Life Spinal Cord Research Foundation,Wings for Life Spinal Cord Research Foundation(Austria);California Institute of Regenerative Medicine(CIRM);International Spinal Research Trust(United Kingdom);Stanford University Bio-X Program Interdisciplinary Initiatives Seed Grant IIP-7;Dennis Chan Foundation;Klein Family Fund;Lucile Packard Foundation for Children's Health;Stanford Institute for Neuro-Innovation and Translational Neurosciences(SINTN);Saunders Family Neuroscience Fund;James Doty Neurosurgery Fund;Hearst Neuroscience Fund;Eileen Bond Research Fund(to GP)。
In recent years,the progression of stem cell therapies has shown great promise in advancing the nascent field of regenerative medicine.Considering the non-regenerative nature of the mature central nervous system,the c...
关键词：axon regeneration central nervous system regeneration induced pluripotent stem cells NEUROTRAUMA regenerative medicine spinal cord injury stem cell therapy 
Neurogenic potential of NG2 in neurotrauma:a systematic review
《Neural Regeneration Research》2024年第12期2673-2683,共11页Yuri R.Rigo Radharani Benvenutti Luis V.Portela Nathan R.Strogulski 
supported by funding from FAPERGS under Grant No.1010267;FAPERGS/PPSUS;No.17/2551-0001;FAPERGS/PRONEX;No.16/2551-0000499-4;FAPERGS/CAPES under Grant No.19/25510000717-5;Conselho Nacional de Desenvolvimento Científico e Tecnologico under Grants Nos.4011645/2012-6 and#5465346/2014-6;Irish Research Council Government of Ireland Postdoctoral Fellowship;No.GOIPD/2022/792;Irish Research Council Enterprise Postdoctoral Fellowship;No.EPSPD/2022/112。
Regenerative approaches towards neuronal loss following traumatic brain or spinal cord injury have long been considered a dogma in neuroscience and remain a cutting-edge area of research.This is reflected in a large d...
关键词：neural-glial antigen 2 neural-glial factor 2 neuron differentiation NG2 cell regeneration spinal cord injury(SCI) traumatic brain injury(TBI) 
Neutrophil extracellular traps mediate neuro-immunothrombosis被引量：2
《Neural Regeneration Research》2024年第8期1734-1740,共7页Jianbo Lou Jianning Zhang Quanjun Deng Xin Chen 
supported by the National Natural Science Foundation of China,No.82271399(to XC);the Project of Tianjin Applied Basic and Multiple Support Research,No.21JCZDJC00910(to XC);the Scientific Research Program of Tianjin Education Commission(Natural Science)of China,No.2019ZD034(to QD);the Science&Technology Program of Tianjin for Cultivation of Innovative Talents,No.22JRRCRC00020(to QD);the Tianjin Medical University"Clinical Talent Training 123 Climbing Plan"(to XC);the Tianjin Health Care Elite Prominent Young Doctor Development Program(to XC);the Young and Middle-aged Backbone Innovative Talent Program(to XC)。
Neutrophil extracellular traps are primarily composed of DNA and histones and are released by neutrophils to promote inflammation and thrombosis when stimulated by various inflammato ry reactions.Neutrophil extracellu...
关键词：inflammation neuro-immunothrombosis neurologic diseases NEUROTRAUMA neutrophil extracellular traps PLATELET THROMBOSIS traumatic brain injury 
Mechanisms of vascular injury in neurotrauma: A critical review of the literature
《World Journal of Meta-Analysis》2024年第3期6-16,共11页Jonathan Willman Annu Lisa Kurian Brandon Lucke-Wold 
One in every two individuals will experience a traumatic brain injury in their lifetime with significant impacts on the global economy and healthcare system each year.Neurovascular injury is a key aspect of neurotraum...
关键词：NEUROTRAUMA Neurovascular injury Primary neurotrauma Secondary neurotrauma Traumatic brain injury Traumatic spinal cord injury Glymphatic system Vascular Injury 
Basal cisternostomy for traumatic brain injury: A case report of unexpected good recovery被引量：1
《Chinese Journal of Traumatology》2022年第5期302-305,共4页Manuel De Jesus Encarnacion Ramirez Rossi Evelyn Barrientos Castilo Anton Vorobiev Nikita Kiselev Amaya Alvarez Aquino Ibrahim E.Efe 
In subarachnoid hemorrhage following traumatic brain injury (TBI), the high intracisternal pressure drives the cerebrospinal fluid into the brain parenchyma, causing cerebral edema. Basal cisternostomy involves openin...
关键词：Basal cisternostomy Cerebral edema Decompressive craniectomy NEUROTRAUMA Traumatic brain injury 
Critical role of mitochondrial aldehyde dehydrogenase 2 in acrolein sequestering in rat spinal cord injury被引量：2
《Neural Regeneration Research》2022年第7期1505-1511,共7页Seth A.Herr Liangqin Shi Thomas Gianaris Yucheng Jiao Siyuan Sun Nick Race Scott Shapiro Riyi Shi 
supported by a grant from National Institute of Neurological Disorders and Stroke R21(No.1R21NS115094-01)。
Lipid peroxidation-derived aldehydes,such as acrolein,the most reactive aldehyde,have emerged as key culprits in sustaining post-spinal cord injury(SCI)secondary pathologies leading to functional loss.Strong evidence ...
关键词：ACROLEIN acrolein-lysine adduct alda-1 enzymatic catalyst lipid peroxidation mitochondrial aldehyde dehydrogenase-2 NEUROTRAUMA oxidative stress reactive aldehydes spinal cord contusion 
Rapid GFAP and Iba1 expression changes in the female rat brain following spinal cord injury被引量：3
《Neural Regeneration Research》2022年第2期378-385,共8页Mawj Mandwie Jordan A.Piper Catherine A.Gorrie Kevin A.Keay Giuseppe Musumeci Ghaith Al-Badri Alessandro Castorina 
The University of Technology Sydney(UTS)Start-up Research Grant 2018 funded this study(to AC)。
Evidence suggests that rapid changes to supporting glia may predispose individuals with spinal cord injury(SCI) to such comorbidities. Here, we interrogated the expression of astrocyte-and microglial-specific markers ...
关键词：affective disorders ASTROCYTES glial fibrillary acidic protein ionized calcium binding adaptor molecule 1 memory MICROGLIA NEUROTRAUMA spinal cord injury 
Central nervous system injury meets nanoceria:opportunities and challenges
《Regenerative Biomaterials》2022年第1期1001-1017,共17页Wang Yang Maoting Zhang Jian He Mingfu Gong Jian Sun Xiaochao Yang 
supported by the Pre-research Project(2020XYY15)of Army Medical University。
Central nervous system(CNS)injury,induced by ischemic/hemorrhagic or traumatic damage,is one of the most common causes of death and long-term disability worldwide.Reactive oxygen and nitrogen species(RONS)resulting in...
关键词：nanoceria reactive oxygen species central nervous system injury STROKE NEUROTRAUMA 
Mechanism of olfactory deficit in neurotrauma and its related affective distress: A narrative review被引量：1
《World Journal of Psychiatry》2021年第12期1259-1266,共8页Mark Logan Siddharth Kapoor Luke Peterson Martin Oliveira Dong Y Han 
Traumatic brain injury(TBI)is among the leading causes of death and disability all over the globe.TBI is also commonly associated with clinical sequelae of posttraumatic depression,and reports of other subsequent affe...
关键词：Brain injuries Brain injuries traumatic ANOSMIA Depression Affective symptoms Smell 
Epidemiology and Challenges of Neurotraumas Care in the Emergency Department of a Semi-Urban Hospital in Guinea, West Africa被引量：1
《Open Journal of Modern Neurosurgery》2021年第3期129-136,共8页I. S. Souaré K. Kaba A. B. Bah I. Berete B. D. Tama I. S. Souaré L. K. Beavogui 
Trauma is one of the most common surgical emergencies admitted in the acute care departments of hospitals in Guinea, West Africa. We carried a study to assess the epidemiological pattern and clinical care of neurotrau...
关键词：NEUROTRAUMA GUINEA Rural Motor Vehicle Accident Emergency Department 
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