Mechanisms of vascular injury in neurotrauma: A critical review of the literature  

作　　者：Jonathan Willman Annu Lisa Kurian Brandon Lucke-Wold 

机构地区：[1]College of Medicine,University of Florida,Gainesville,FL 32610,United States [2]College of Medicine,Florida State University,Tallahassee,FL 32304,United States [3]Department of Neurosurgery,University of Florida,Gainesville,FL 32611,United States

出　　处：《World Journal of Meta-Analysis》2024年第3期6-16,共11页世界荟萃分析杂志

摘　　要：One in every two individuals will experience a traumatic brain injury in their lifetime with significant impacts on the global economy and healthcare system each year.Neurovascular injury is a key aspect of neurotrauma to both the brain and the spinal cord and an important avenue of current and future research seeking innovative therapies.In this paper,we discuss primary and secondary neurotrauma,mechanisms of injury,the glymphatic system,repair and recovery.Each of these topics are directly connected to the vasculature of the central ner-vous system,affecting severity of injury and recovery.Consequently,neurova-scular injury in trauma represents a promising target for future therapeutics and innovation.

关 键 词：NEUROTRAUMA Neurovascular injury Primary neurotrauma Secondary neurotrauma Traumatic brain injury Traumatic spinal cord injury Glymphatic system Vascular Injury 

分 类 号：R873[医药卫生—运动医学]