PHOTORECEPTOR

作品数:87被引量:120H指数:6
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相关领域:医药卫生生物学更多>>
相关作者:管玉圣欧阳杰郭爱克叶亦舟何永歆更多>>
相关机构:华中科技大学重庆市农业科学院南京医科大学中国科学院上海生命科学研究院更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划天津市自然科学基金安徽省自然科学基金更多>>
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Contribution of ferroptosis and SLC7A11 to light-induced photoreceptor degeneration
《Neural Regeneration Research》2026年第1期406-416,共11页Xiaoxu Huang Yumeng Zhang Yuxin Jiang Tong Li Shiqi Yang Yimin Wang Bo Yu Minwen Zhou Guanran Zhang Xiaohuan Zhao Junran Sun Xiaodong Sun 
supported by the National Natural Science Foundation of China,Nos. 82171076 (to XS) and U22A20311 (to XS), 82101168 (to TL);Shanghai Science and technology Innovation Action Plan,No. 23Y11901300 (to JS);Science and Technology Commission of Shanghai Municipality,No. 21ZR1451500 (to TL);Shanghai Pujiang Program,No. 22PJ1412200 (to BY)。
Progressive photoreceptor cell death is one of the main pathological features of age-related macular degeneration and eventually leads to vision loss. Ferroptosis has been demonstrated to be associated with retinal de...
关键词:age-related macular degeneration ferroptosis light exposure damage oxidative stress pathway PHOTORECEPTOR programmed cell death solute carrier family 7 member 11(SLC7A11) 
The dark activity of Arabidopsis blue-light receptor CRY2
《Science China(Life Sciences)》2025年第3期887-889,共3页Gao-Ping Qu Zeru Zhang Chentao Lin 
supported by the National Natural Science Foundation of China(32330009,32000155).
The functions of photoreceptors have been extensively investigated over the last two decades.However,whether those photoreceptors have any functions in the absence of light remained unclear.Recently,Prof.Hongtao Liu’...
关键词:PHOTORECEPTOR CRY2 ARABIDOPSIS 
Age-related driving mechanisms of retinal diseases and neuroprotection by transcription factor EB-targeted therapy
《Neural Regeneration Research》2025年第2期366-377,共12页Samuel Abokyi Dennis Yan-yin Tse 
supported by the Start-up Fund for new faculty from the Hong Kong Polytechnic University(PolyU)(A0043215)(to SA);the General Research Fund and Research Impact Fund from the Hong Kong Research Grants Council(15106018,R5032-18)(to DYT);the Research Center for SHARP Vision in PolyU(P0045843)(to SA);the InnoHK scheme from the Hong Kong Special Administrative Region Government(to DYT).
Retinal aging has been recognized as a significant risk factor for various retinal disorders,including diabetic retinopathy,age-related macular degeneration,and glaucoma,following a growing understanding of the molecu...
关键词:age-related macular degeneration anti-aging interventions autophagy calorie restriction diabetic retinopathy exercise glaucoma NEUROMODULATION PHAGOCYTOSIS photoreceptor outer segment degradation retinal aging transcription factor EB 
The retinal pigment epithelium:Functions and roles in ocular diseases
《Fundamental Research》2024年第6期1710-1718,共9页Shasha Wang Wanhong Li Min Chen Yihai Cao Weisi Lu Xuri Li 
supported by the State Key Laboratory of Ophthalmology,Zhongshan Ophthalmic Center,Sun Yat-Sen University,Guangzhou,China;the National Key R&D Program of China(2023YFC2506100 to X.L.);the National Natural Science Foundation of China(82150710555 and 82220108016 to X.L.);the Natural Science Foundation of Guangdong Province grant(2021A1515010684 to W.L.);the Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science(2020B1212060033 to W.L.),and the Guangzhou Basic Research Program(2023A03J0182 to W.L.).
The retinal pigment epithelium(RPE)between retinal photoreceptors and choroidal capillaries is a single layer of cells that are of critical importance to the eye.RPE cells are derived from the anterior neural plate of...
关键词:Retinal pigment epithelium RETINA PHOTORECEPTOR CHOROID Ocular disease Bloodretinal barrier 
Impaired pericyte-Müller glia interaction via PDGFRβ suppression aggravates photoreceptor loss in a rodent model of light-induced retinal injury
《International Journal of Ophthalmology(English edition)》2024年第10期1800-1808,共9页Wei Xu Li-Jin Cui Xiao-Ying Yang Xiao-Yuan Cui Jian Guo Guo-Xing Xu 
Supported by National Natural Science Foundation of China(No.81900862)。
AIM:To investigate the involvement of pericyte-Müller glia interaction in retinal damage repair and assess the influence of suppressing the platelet-derived growth factor receptorβ(PDGFRβ)signaling pathway in retin...
关键词:PERICYTE Müller glia light-induced retinal injury platelet-derived growth factor receptorβ signal pathway 
Protective effects of CY-09 and astaxanthin on NaIO_(3)-induced photoreceptor inflammation via the NLRP3/autophagy pathway
《International Journal of Ophthalmology(English edition)》2024年第7期1217-1231,共15页Xiao-Li Wang Yun-Xia Gao Qiong-Zhen Yuan Ming Zhang 
Supported by the National Key R&D Project(No.2018YFC1106103);Project of Sichuan Medical Association(No.S22058).
AIM:To study the effect of the NLRP3/autophagy pathway on the photoreceptor inflammatory response and the protective mechanism of CY-09 and astaxanthin(AST).METHODS:ICR mice were intraperitoneally injected NaIO_(3),CY...
关键词:CY-09 ASTAXANTHIN retinal degeneration photoreceptor cells INFLAMMATION NLRP3 
Retinitis pigmentosa and stem cell therapy
《International Journal of Ophthalmology(English edition)》2024年第7期1363-1369,共7页Xin-Ya Qi Chen-Hui Mi De-Rui Cao Xie-Qun Chen Peng Zhang 
Retinitis pigmentosa(RP)is a group of genetic disorders characterized by progressive degeneration of photoreceptors and retinal pigment epithelium(RPE)cells.Its main clinical manifestations include night blindness and...
关键词:retinitis pigmentosa PHOTORECEPTOR stem cell therapy 
Plant photobiology: From basic theoretical research to crop production improvement
《Journal of Integrative Plant Biology》2024年第5期847-848,共2页Hongtao Liu Jigang Li 
As one of the most important environmental signals for plants,light plays a profound role in regulating virtually every aspect of plant growth and development.Light signals are perceived by plants via several families...
关键词:UVR8 PHOTORECEPTOR DEVELOPMENT 
The endoplasmic reticulum membrane protein complex subunit Emc6 is essential for rhodopsin localization and photoreceptor cell survival
《Genes & Diseases》2024年第2期1035-1049,共15页Kuanxiang Sun Lu Liu Xiaoyan Jiang Heting Wang Lin Wang Yeming Yang Wenjing Liu Lin Zhang Xiaohui Zhao Xianjun Zhu 
supported by The National Natural Science Foundation of China(No.82121003,81970841,82101160);the program of Science and Technology International Cooperation Project of Qinghai province(China)(No.2022-HZ-814);the CAMS Innovation Fund for Medical Sciences(No.2019-12M-5-032);Sichuan Intellectual Property Office(China)(No.2022-ZS-0070);the Department of Chengdu Science and Technology(Sichuan,China)(No.2021-YF05-01316-SN).
The endoplasmic reticulum(ER)membrane protein complex(EMC)is responsible for monitoring the biogenesis and synthetic quality of membrane proteins with tail-anchored or multiple transmembrane domains.The EMC subunit EM...
关键词:ANO2 CILIUM EMC6 ER membrane protein complex Mislocalization Photoreceptor degeneration TMEM67 
The GmSTF1/2–GmBBX4 negative feedback loop acts downstream of blue-light photoreceptors to regulate isoflavonoid biosynthesis in soybean
《Plant Communications》2024年第2期198-214,共17页Zhaoqing Song Fengyue Zhao Li Chu Huan Lin Yuntao Xiao Zheng Fang Xuncheng Wang Jie Dong Xiangguang Lyu Deyue Yu Bin Liu Junyi Gai Dongqing Xu 
supported by the Natural Science Foundation of Jiangsu for Distinguished Young Scholars (BK20211525);the National Natural Science Foundation of China (32270256,31970258);the Core Technology Development for Breeding Program of Jiangsu Province (JBGS-2021-014);the Jiangsu Collaborative Innovation Center for Modern Crop Production (to D.X.);Nanjing Agricultural University (start-up funding to D.X.).
Isoflavonoids,secondary metabolites derived from the phenylalanine pathway,are predominantly bio-synthesized in legumes,especially soybean(Glycine max).They are not only essential for plant responses to biotic and abi...
关键词:PHOTORECEPTOR light signaling ISOFLAVONOID GmSTF GmBBX4 SOYBEAN 
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