supported by the Inha University Research Grant(to JKR).
Pericytes are multifunctional mural cells that surround the abluminal wall of endothelial cells and are associated with vascular development,vascular permeability,and angiogenesis.Additionally,pericytes demonstrate st...
supported by grants from the National Natural Science Foundation of China(Grant No. 82070983);the Natural Science Foundation of Jiangsu Province (Grant No.BK20211020);grants from the Medical Science and Technology Development Project Fund of Nanjing (Grant No. YKK22263)
Pericytes are located in the stromal membrane of the capillary outer wall and contain endothelial cells.They are pivotal in regulating blood flow,enhancing vascular stability,and maintaining the integrity of the blood...
supported by the National Key R&D Program of China(2019YFA0801603 to J.L.);National Natural Science Foundation of China(31701265 to X.P.);Shanghai Natural Science Foundation(22ZR1469700 to J.L.);SA-SIBS Scholarship Program(to J.L.);Youth Innovation Promotion Association of Chinese Academy of Sciences(to J.L.)。
Pericytes,the mural cells enveloping small vessels,play a crucial role in maintaining the integrity of the blood-brain barrier(BBB)(Armulik et al.,2010;Daneman et al.,2010).Their loss leads to significant defects in B...
Supported by National Natural Science Foundation of China(No.81900862)。
AIM:To investigate the involvement of pericyte-Müller glia interaction in retinal damage repair and assess the influence of suppressing the platelet-derived growth factor receptorβ(PDGFRβ)signaling pathway in retin...
supported by the Key Projects and Innovation Group of National Natural Science Foundation of China(81830065),the Innovation Groups of NSFC(81721001),and the Young Scientists Fund(82102279).
Background Vascular hyporeactivity and leakage are key pathophysiologic features that produce multi-organ damage upon sepsis.We hypothesized that pericytes,a group of pluripotent cells that maintain vascular integrity...
Neurological Foundation First Fellowship(2244 FFE)(to TJS);Health Research Council Hercus(21/034);a Neurologicalgrant(2026PRG);School of Medical Science,University of Auckland(to BVD)。
Pericytes are classically defined as contra ctile cells within the central nervous system that regulate blood flow and permeability of the blood-brain barrier(BBB).This one-sided view is gradually changing,and pericyt...
supported partly by the National Natural Science Foundation of China(Grant Nos.82073064 and 81874167 to LYL,and 82073233 to ZQZ);Haihe Laboratory of Cell Ecosystem Innovation Fund(Grant No.22HHXBSS00020 to LYL);Ministry of Education 111 Project(Grant No.B20016 to LYL)。
Objective:Immature vasculature lacking pericyte coverage substantially contributes to tumor growth,drug resistance,and cancer cell dissemination.We previously demonstrated that tumor necrosis factor superfamily 15(TNF...
This work was supported by the National Natural Science Foundation of China(32000670 and 82071779);Chongqing Research Program of Basic Research and Frontier Technology(cstc2017jcyjAX0338).
The brain pericyte is a unique and indispensable part of the blood-brain barrier(BBB),and contributes to several pathological processes in traumatic brain injury(TBI).However,the cellular and molecular mechanisms by w...
supported by startup funds from Medical College of Georgia at Augusta University(to HL);National Institutes of Health R01NS117918,R21NS104394,and R21NS119732(to HL)。
Spinal cord injury represents a devastating central nervous system injury that could impair the mobility and sensory function of afflicted patients.The hallmarks of spinal cord injury include neuroinflammation,axonal ...
partly supported by a research grant from the National Natural Science Funding of China (82172424,81972150,82172428);Zhejiang Medical and Health Science,and Technology Plan Project (2021KY212);supported in part by the Australian Health and Medical Research Council (NHMRC,No. 1107828)
Vascular regeneration is a challenging topic in tissue repair. As one of the important components of the neurovascular unit(NVU),pericytes play an essential role in the maintenance of the vascular network of the spina...