supported by project Emerging Infectious Diseases One Health Basic and Translational Research Actions addressing Unmet Needs on Emerging Infectious Diseases,INF-ACT,Spoke 1 and Spoke 5,Project number PE00000007,CUP B53C20040570005(to PP and DN).
Introduction:One of the main events that regulate a cell’s well-being is cell-to-cell communication.This intercellular mechanism of information transfer is often mediated by vesicular trafficking.Mitochondrial-derive...
supported by the Natural Science Foundation of Chongqing,No.CSTB2023NSCQ-mSX0561(to WL).
Effective treatment methods for stroke,a common cerebrovascular disease with a high mortality rate,are still being sought.Exosome therapy,a form of acellular therapy,has demonstrated promising efficacy in various dise...
Metastasis remains a critical challenge in cancer treatment and the leading cause of cancer-related mortality.Ongoing research has demonstrated the key role of extracellular vesicles(EVs)in facilitating communication ...
supported by the National Natural Science Foundation of China,Nos.81901098(to TC),82201668(to HL);Fujian Provincial Health Technology Project,No.2021QNA072(to HL)。
The central nervous system, information integration center of the body, is mainly composed of neurons and glial cells. The neuron is one of the most basic and important structural and functional units of the central n...
Natural Science Foundation of Changsha city,China,Grant/Award Number:kq2403166;Hunan Provincial Clinical Medical Technology Innovation Guiding Project,Grant/Award Number:2020SK53307;Basic Public Welfare Research projects of Wenzhou Science and Technology Bureau,Grant/Award Number:Y20240087;Natural Science Foundation of Hunan Province,Grant/Award Number:2020JJ8043;Start-up Funding for Talented Scientific Research of the First Affiliated Hospital of Wenzhou Medical University,Grant/Award Number:2023QD026;Key Project of Hunan Provincial Health Commission,Grant/Award Number:20201902 and C2019133;National Natural Science Foundation of China,Grant/Award Number:82472495。
Background:Osteoarthritis(OA)is a long-term degenerative joint disease worsen-ing over time.Aging and chondrocyte senescence contribute to OA progression.MicroRNAs have been confirmed to regulate different cellular pr...
BACKGROUND Cold-inducible RNA-binding protein(CIRP)is related to a family of stressinduced RNA-binding proteins.It is primarily found in the nucleus,where it regulates transcription.Under stress,CIRP translocates to t...
supported by the National Cancer Institute(grants R01CA230339 and R37CA255948).
Extracellular vesicles(EVs)are lipid bilayer-enclosed vesicles released by cells.EVs encapsulate proteins and nucleic acids of their parental cell and efficiently deliver the cargo to recipient cells.These vesicles ac...
supported by the National Natural Science Foundation of China(82073756).
Epstein-Barr virus(EBV),the first identified human tumor virus,is implicated in various human malignancies,infectious mononucleosis,and more recently,multiple sclerosis.Prophylactic vaccines have the potential to effe...
supported by grants from the National Natural Science Foundation of China(grant numbers:82001045,82122014,82020108011,82071085)。
The oral and maxillofacial region is a highly complex area composed of multiple tissue types and bears various critical functions of the human body.Diseases in this region pose significant diagnostic and management ch...
Southern Illinois University,Carbondale,IL;Ministry of Higher Education&Scientific Research,Baghdad,Iraq;NIFA-USDA Hatch project accession#1016077(Multistate#W4171);USDAARS project 6066-31000-015-00D;NIH MS-IDeA network of Biomedical Research Excellence award 5P20GMI03476-19.GMI received a PhD scholarship from the Ministry of Higher Education&Scientific Research,Baghdad,Iraq.
Background Ovarian follicular fluid(FF)is a dynamic environment that changes with the seasons,affecting follicle development,ovulation,and oocyte quality.Cells in the follicles release tiny particles called extracellu...