EXTRACELLULAR

作品数:493被引量:1723H指数:16
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相关领域:医药卫生更多>>
相关作者:廖成水程相朝徐军丁宁杨利娟更多>>
相关机构:河南科技大学河北师范大学上海交通大学附属第六人民医院东南大学更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划中国博士后科学基金广东省自然科学基金更多>>
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Mitochondria-derived vesicles:New players in the game of neurodegeneration
《Neural Regeneration Research》2026年第2期679-680,共2页Laura Palumbo Domenico Nuzzo Antonella Girgenti Pasquale Picone 
supported by project Emerging Infectious Diseases One Health Basic and Translational Research Actions addressing Unmet Needs on Emerging Infectious Diseases,INF-ACT,Spoke 1 and Spoke 5,Project number PE00000007,CUP B53C20040570005(to PP and DN).
Introduction:One of the main events that regulate a cell’s well-being is cell-to-cell communication.This intercellular mechanism of information transfer is often mediated by vesicular trafficking.Mitochondrial-derive...
关键词:extracellular vesicles cell cell communication vesicular traffickingmitochondrial derived NEURODEGENERATION mitochondria derived vesicles vesicular trafficking extracellular vesicle ev first 
Exosomes in stroke management:A promising paradigm shift in stroke therapy
《Neural Regeneration Research》2026年第1期6-22,共17页Bo Wang Pinzhen Chen Wenyan Li Zhi Chen 
supported by the Natural Science Foundation of Chongqing,No.CSTB2023NSCQ-mSX0561(to WL).
Effective treatment methods for stroke,a common cerebrovascular disease with a high mortality rate,are still being sought.Exosome therapy,a form of acellular therapy,has demonstrated promising efficacy in various dise...
关键词:angiogenesis animal model cerebrovascular disorder extracellular vesicle mortality rates neural stem cell NEUROINFLAMMATION oxidative stress programmed cell death therapy 
Exploring the significance of extracellular vesicles:Key players in advancing cancer and possible theranostic tools
《Cancer Pathogenesis and Therapy》2025年第2期109-119,共11页Bhaumik Patel Shreyas Gaikwad Sahdeo Prasad 
Metastasis remains a critical challenge in cancer treatment and the leading cause of cancer-related mortality.Ongoing research has demonstrated the key role of extracellular vesicles(EVs)in facilitating communication ...
关键词:Extracellular vesicle(EV) Cancer metastasis BIOMARKER Bioengineered EV 
Potassium and calcium channels in different nerve cells act as therapeutic targets in neurological disorders
《Neural Regeneration Research》2025年第5期1258-1276,共19页Qing Qiu Mengting Yang Danfeng Gong Haiying Liang Tingting Chen 
supported by the National Natural Science Foundation of China,Nos.81901098(to TC),82201668(to HL);Fujian Provincial Health Technology Project,No.2021QNA072(to HL)。
The central nervous system, information integration center of the body, is mainly composed of neurons and glial cells. The neuron is one of the most basic and important structural and functional units of the central n...
关键词:ASTROCYTES calcium channels central nervous system extracellular ion concentration MICROGLIA neurological disorders NEURONS potassium channels 
The miR-6779/XIAP axis alleviates IL-1β-induced chondrocyte senescence and extracellular matrix loss in osteoarthritis
《Animal Models and Experimental Medicine》2025年第4期662-673,共12页Zongchao Li Aonan Dai Xiaoxiang Fang Kexing Tang Kun Chen Peng Gao Jingyue Su Xin Chen Shengwu Yang Zhenhan Deng Liangjun Li 
Natural Science Foundation of Changsha city,China,Grant/Award Number:kq2403166;Hunan Provincial Clinical Medical Technology Innovation Guiding Project,Grant/Award Number:2020SK53307;Basic Public Welfare Research projects of Wenzhou Science and Technology Bureau,Grant/Award Number:Y20240087;Natural Science Foundation of Hunan Province,Grant/Award Number:2020JJ8043;Start-up Funding for Talented Scientific Research of the First Affiliated Hospital of Wenzhou Medical University,Grant/Award Number:2023QD026;Key Project of Hunan Provincial Health Commission,Grant/Award Number:20201902 and C2019133;National Natural Science Foundation of China,Grant/Award Number:82472495。
Background:Osteoarthritis(OA)is a long-term degenerative joint disease worsen-ing over time.Aging and chondrocyte senescence contribute to OA progression.MicroRNAs have been confirmed to regulate different cellular pr...
关键词:CHONDROCYTE miR-6779 OSTEOARTHRITIS SENESCENCE X-linked inhibitor of apoptosis protein 
Plasma extracellular cold inducible RNA-binding protein levels are elevated for 1 month post-colectomy which may promote metastases
《World Journal of Gastrointestinal Oncology》2025年第4期318-326,共9页H M C Shantha Kumara Poppy Addison Xiao-Hong Yan Anuj Raj Sharma Neil Mitra Hansani N Angammana Yanni Hedjar Yi-Ru Chen Vesna Cekic Whelan L Richard 
BACKGROUND Cold-inducible RNA-binding protein(CIRP)is related to a family of stressinduced RNA-binding proteins.It is primarily found in the nucleus,where it regulates transcription.Under stress,CIRP translocates to t...
关键词:Effects of surgery Plasma extracellular cold-inducible RNA-binding protein levels Colorectal resection Colorectal cancer Angiogenesis 
Strategies for Small Extracellular Vesicle-Based Cancer Immunotherapy
《Research》2025年第1期765-781,共17页Yundi Chen Shasha Tang Fengfeng Cai Yuan Wan 
supported by the National Cancer Institute(grants R01CA230339 and R37CA255948).
Extracellular vesicles(EVs)are lipid bilayer-enclosed vesicles released by cells.EVs encapsulate proteins and nucleic acids of their parental cell and efficiently deliver the cargo to recipient cells.These vesicles ac...
关键词:extracellular vesicles therapeutic agents liquid biopsy extracellular vesicles evs drug delivery mediators intercellular communication drug delivery vehiclestherapeutic agentsand cancer immunotherapy 
An insect cell-derived extracellular vesicle-based gB vaccine elicits robust adaptive immune responses against Epstein-Barr virus
《Science China(Life Sciences)》2025年第3期734-745,共12页Qian Wu Kaiyun Chen Wenhui Xue Guosong Wang Yanbo Yang Shaowei Li Ningshao Xia Yixin Chen 
supported by the National Natural Science Foundation of China(82073756).
Epstein-Barr virus(EBV),the first identified human tumor virus,is implicated in various human malignancies,infectious mononucleosis,and more recently,multiple sclerosis.Prophylactic vaccines have the potential to effe...
关键词:Epstein-Barr virus glycoprotein gB extracellular vesicle humoral immune responses cellular immune responses 
Emerging roles of extracellular vesicles in oral and maxillofacial areas
《International Journal of Oral Science》2025年第1期32-51,共20页Qianting Wang Jiayu Sun Haci Jiang Mengfei Yu 
supported by grants from the National Natural Science Foundation of China(grant numbers:82001045,82122014,82020108011,82071085)。
The oral and maxillofacial region is a highly complex area composed of multiple tissue types and bears various critical functions of the human body.Diseases in this region pose significant diagnostic and management ch...
关键词:DIAGNOSIS SPECIFICITY EXTRACELLULAR 
Seasonal influence on miRNA expression dynamics of extracellular vesicles in equine follicular fluid
《Journal of Animal Science and Biotechnology》2025年第1期136-152,共17页Jean M.Feugang Ahmed Gad Nico G.Menjivar Ghassan M.Ishak Samuel Gebremedhn Melba O.Gastal Notsile H.Dlamini Radek Prochazka Eduardo L.Gastal Dawit Tesfaye 
Southern Illinois University,Carbondale,IL;Ministry of Higher Education&Scientific Research,Baghdad,Iraq;NIFA-USDA Hatch project accession#1016077(Multistate#W4171);USDAARS project 6066-31000-015-00D;NIH MS-IDeA network of Biomedical Research Excellence award 5P20GMI03476-19.GMI received a PhD scholarship from the Ministry of Higher Education&Scientific Research,Baghdad,Iraq.
Background Ovarian follicular fluid(FF)is a dynamic environment that changes with the seasons,affecting follicle development,ovulation,and oocyte quality.Cells in the follicles release tiny particles called extracellu...
关键词:Extracellular vesicle Follicle growth Follicular fluid HORSE MARE OVULATION Pre-ovulation Seasonal breeding 
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