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Targeting Wallerian degeneration in glaucoma: 《Neural Regeneration Research》2026年第2期693-694,共2页Melissa Jöe Pete A.Williams; supported by St.Erik Eye Hospital philanthropic donations,Vetenskapsrådet 2022-00799(to PAW).; Neurodegenerative diseases account for a large and increasing health and economic burden worldwide.With an increasingly aged population,this burden is set to increase.Optic neuropathies make up a large proportion of n...; 关键词：health burden neurodegenerative diseases aged population Wallerian degeneration GLAUCOMA vision loss economic burden retinal ganglion cells their axons

Bidirectional causality of physical exercise in retinal neuroprotection: 《Neural Regeneration Research》2025年第12期3400-3415,共16页Stephen K.Agadagba Suk-yu Yau Ying Liang Kristine Dalton Benjamin Thompson; supported by the InnoHK Initiative and the Hong Kong Special Administrative Region Government, China (to SYY)。; Physical exercise is recognized as an effective intervention to improve mood,physical performance,and general well-being.It achieves these benefits through cellular and molecular mechanisms that promote the release of...; 关键词：age-related macular degeneration biomarkers diabetic retinopathy GLAUCOMA neuroprotective factors ocular diseases physical exercise retinal neuroprotection retinitis pigmentosa visual impairment

Polymorphic variants of ABCA1, PMM2, and ARHGEF12 genes and the risk of glaucoma in an Iranian population: 《International Journal of Ophthalmology(English edition)》2025年第5期846-852,共7页Asghar Shayannia Kobra Foroughi Mohammad Hassan Emamian Hassan Hashemi Akbar Fotouhi; Supported by the Noor Ophthalmology Research Center and Shahroud University of Medical Sciences(No.9449);Shahroud University of Medical Sciences(No.9449);Shahroud Eye Cohort Study is supported by the Noor Ophthalmology Research Center and Shahroud University of Medical Sciences(No.8737).; AIM:To examine whether rs2472493 and rs248032 in the ABCA1 gene,rs3785176 in the PMM2 gene,and rs11827818 in the ARHGEF12 gene contribute to primary open angle glaucoma(POAG)in an Iranian population.METHODS:Totally 82...; 关键词：ABCA1 PMM2 ARHGEF12 rs2472493 rs248032 rs3785176 rs11827818 Iran primary open angle glaucoma

Aqueous humor adipokine profile of primary open angle glaucoma patients and cataract patients with or without metabolic disorders: 《International Journal of Ophthalmology(English edition)》2025年第4期615-626,共12页Zi-Yao Xia Ke Xu Wei-Jia Zhang De-Fu Wu Zhe Pan Hao-Cheng Xian Xue-Min Li Huai-Zhou Wang Chun Zhang; Supported by National Key R&D Program of China(No.2023YFC2506100);the Changping Key Research Project of the Beijing Natural Science Foundation Program(No.L234016).; AIM:To investigate the role of adipokines in primary open angle glaucoma(POAG)by comparing the levels of these molecules in the aqueous humor among POAG patients and cataract patients with or without metabolic disorde...; 关键词：glaucoma biomarkers ADIPOKINE primary open angle glaucoma aqueous humor metabolic disorder

Navigating decisional conflict:laser peripheral iridotomy for primary angle-closure glaucoma prevention: 《International Journal of Ophthalmology(English edition)》2025年第4期627-636,共10页Yi-Jie Chen Jing-Yao Dai Rong-Rong Le Xiao-Xian Zhang Jia-Li Huang Hu-Jie Lu Yi-Wen Sun Yuan-Bo Liang Yan-Yan Chen Wen-Zhe Zhou; Supported by Basic Scientific Research Projects of Wenzhou(No.Y20220155).; AIM:To investigate decisional conflict among patients diagnosed with primary angle-closure suspect(PACS)or primary angle-closure(PAC)who are considering laser peripheral iridotomy(LPI)treatment.METHODS:A total of 111 ...; 关键词：GLAUCOMA primary angle-closure suspect primary angle-closure laser peripheral iridotomy decisional conflict

Bleb revision and transscleral cyclophotocoagulation for congenital glaucoma patient with Turner syndrome and DMPK gene mutation:a case report: 《International Journal of Ophthalmology(English edition)》2025年第4期744-747,共4页An-Qi Guo Wei-Jia Zhang Ying Hong Chun Zhang; Supported by Innovation&Transfer Fund of Peking University Third Hospital(No.Y77448-06).; Dear Editor,We report a case of congenital glaucoma patient with Turner syndrome(TS)and DMPK gene mutation whose intraocular pressure(IOP)was controlled by multiple bleb revision with antiproliferation medication foll...; 关键词：TURNER CONGENITAL GLAUCOMA

A Nature-Inspired AI Framework for Accurate Glaucoma Diagnosis: 《Computer Modeling in Engineering & Sciences》2025年第4期539-567,共29页Jahanzaib Latif Ahsan Wajahat Alishba Tahir Anas Bilal Mohammed Zakariah Abeer Alnuaim; Researchers Supporting Project number(RSP2025R314),King Saud University,Riyadh,Saudi Arabia.; Glaucoma,a leading cause of blindness,demands early detection for effective management.While AI-based diagnostic systems are gaining traction,their performance is often limited by challenges such as varying image back...; 关键词：GLAUCOMA fundus images machine learning nature-inspired algorithm SEGMENTATION classification

Glaucoma animal models in rabbits:State of the art and perspectives-A review: 《Animal Models and Experimental Medicine》2025年第3期429-440,共12页Rong Hu Kai Wu Jian Shi Juan Yu Xiao-lei Yao; The 64th batch of China Postdoctoral Science Foundation,Grant/Award Number:2018M640754;National Natural Science Foundation of China,Grant/Award Number:81860870;The“Wang Heng xin Scientific Research Fund”project of Hunan University of Chinese Medicine,Grant/Award Number:2023HX007。; Glaucoma,a visual thief,is characterized by elevated intraocular pressure(IOP)and the loss of retinal ganglion cells(RGCs).Selecting suitable animals for preclinical models is of great significance in research on the ...; 关键词：aqueous humor outflow GLAUCOMA intraocular pressure rabbit eye anatomy retinal ischemia-reperfusion

Efficacy of ultrasound cyclo-plasty in treatment of glaucoma in Asian population: 《International Journal of Ophthalmology(English edition)》2025年第3期549-556,共8页Ping Ge Jie Yang Jin-Wei Xi Wei Sang Xiang-Xiang Yang Zi-Wei Fu Jun Jia Yuan He; Supported by National Natural Science Foundation of China(No.82070964);Shaanxi Science Fund for Distinguished Young Scholars(No.2022JC-60);the International Scientific and Technological Cooperation Projects(No.2024GH-YBXM-20);Xi’an Medical University Undergraduate Open Experimental Research Fund(No.2024DXS02);Yizhen Genetic Talent Development Program(No.2023YZ10);The Open Research Funds of the State Key Laboratory of Ophthalmology(No.83000-32030002).; As a non-invasive surgical procedure ultrasound cycloplasty(UCP)has gained attention among ophthalmologists in recent years.Derived from the application of highintensity focused ultrasound,it has been utilized for the...; 关键词：ultrasound cyclo-plasty high-intensity focused ultrasound GLAUCOMA Asia populations ciliary body surgery

Monogenic gene therapy for glaucoma and optic nerve injury: 《Neural Regeneration Research》2025年第3期815-816,共2页Chikako Harada Xiaoli Guo Takayuki Harada; supported by Japan Society for the Promotion of Science (JSPS) KAKENHI Grants-in-Aid for Scientific Research (JP22K09804 to CH;JP21K09688 to XG;JP19KK0229, JP21H04786, JP21H02819 and JP21K18279 to TH);the Shiseido Female Researcher Science Grant (to XG);Mitsubishi Foundation;Takeda Science Foundation (to TH)。; The prevalence of glaucoma, the second leading cause of global blindness, is increasing due to aging populations. In glaucoma, degeneration of the optic nerve and retinal ganglion cells(RGCs) causes visual field defec...; 关键词：VISUAL GLAUCOMA DEGENERATION

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