Supported by National Key R&D Program of China(No.2023YFC2506100);the Changping Key Research Project of the Beijing Natural Science Foundation Program(No.L234016).
AIM:To investigate the role of adipokines in primary open angle glaucoma(POAG)by comparing the levels of these molecules in the aqueous humor among POAG patients and cataract patients with or without metabolic disorde...
Introduction:Human chemerin is an adipokine that regulates chemotaxis,inflammation,and glucose metabolism.In addition,accumulating evidence suggests that chemerin promotes apoptosis,autophagy,and pyroptosis.However,th...
Supported by The Faculty of Medicine Research Fund,Chiang Mai University,Thailand,No.017/2564.
BACKGROUND The prevalence of gestational diabetes mellitus(GDM)has been increasing worldwide and is associated with multiple adverse pregnancy outcomes.Despite standard screening,some cases remain undiagnosed.Fibrobla...
supported by National Natural Science Foundation of China(31972582,U22A20516);Science and Technology Innovation Program of Hunan Province(2021RC4039);Key R&D Program of Hunan Province(2022NK2026);the Youth Innovation Promotion Association CAS(Y202079)
This study was conducted to explore the regulatory mechanism of leucine(Leu)on lipid metabolism of finishing pigs.Twenty-four Duroc×Landrace×Large cross pigs with an average body weight of68.33±0.97 kg were randoml...
BACKGROUND Patients with chronic hepatitis C virus(HCV)infection have increased serum omentin-1.Omentin-1 is an anti-inflammatory adipokine,and higher levels may be a direct effect of HCV infection.Successful eliminat...
supported by the Plan Nacional de Investigación Científca,Desarrollo e Innovación Tecnológica(I+D+I);Instituto de Salud Carlos III-Health Research Funding(FONDOS FEDER)(PI051968,PI1102042 and PI1600871);Maria C.Rico is funded by Redes temáticas de Investigación cooperativa RETIC(Red SAMID RD12/0026/0015)and the Mapfre Foundation.
Objectives To evaluate whether there is an association between the serum levels of the novel insulin-like adipokine isthmin-1(ISM1)and obesity-related phenotypes in a population of Spanish children and to investigate ...
supported by grants from the National Natural Science Foundation of China(No.82000792);General Project of Chongqing Natural Science Foundation(China)(No.cstc2020jcyj-msxm0409);Chongqing Science and Technology Bureau and Health Commission of Chinese Medicine Technology Innovation and Application Development Project(China)(No.2020ZY013540);General Project of Graduate Education and Teaching Reform of Chongqing University,Chongqing,China(No.cquyjg20329);Science and Health Joint Project of Dazu District Science and Technology Bureau(China)(No.DZKJ,2022CCC1001).
Metabolic cardiovascular diseases have become a global health concern,and some of their risk factors are linked to several metabolic disorders.They are the leading causes of death in developing countries.Adipose tissu...
The relationship between metabolic derangements and fatty liver development are undeniable,since more than 75% of patients with type 2 diabetes mellitus present with fatty liver.There is also significant epidemiologic...
supported by the National Natural Science Foundation of China(81871607 and 82070422);Youth Science and Technology Rising Star Project of Shaanxi Province(2020KJXX-036);High-end Foreign Expert Introduction Program of National Science and Technology(G2022040014L);Innovation Capability Strong Foundation Plan of Xi'an City(Medical Research Project,21YXYJ0037);Major Research Projects of Xian Science and Technology Plan[201805104YX12SF38(2)].
C1q/tumor necrosis factor(TNF)related proteins(CTRPs)is a newly discovered adipokine family with conservative structure and ubiquitous distribution and is secreted by adipose tissues.Recently,CTRPs have attracted incr...
The research was supported in part by the USA NIDDK DK129234,NIAAA AA026904;NIGMS P20GM144269;P30GM118247(to H.-M.Ni).
Background:Alcohol-associated liver disease(ALD)is a major chronic liver disease around the world without successful treatment.Acute alcoholic hepatitis is one of the most severe forms of ALD with high mortality,which...