MICROENVIRONMENT

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相关机构：首都医科大学宣武医院山东大学中国农业科学院郑州果树研究所常州市武进人民医院更多>>
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Cross-talk between lactate metabolism and immunity reveals CEP55 as a potential regulator in the immunosuppressive microenvironment of hepatocellular carcinoma
《Genes & Diseases》2025年第3期42-45,共4页Jie Li Yuyuan Zhang Jinhai Deng Siyuan Weng Hui Xu Yuhao Ba Anning Zuo Shutong Liu Quan Cheng Jian Zhang Peng Luo Zhen Li Xinwei Han Zaoqu Liu 
supported by the Major Science and Technology projects of Henan Province,China(No.221100310100).
The interaction of lactate metabolism with immunity plays a crucial role in the remodeling of the immune microenvironment and even in the heterogeneous progression of hepatocellular carcinoma(HCC).The intratumor-accum...
关键词：cep hepatocellular carcinoma hepatocellular carcinoma hcc lactate metabolism IMMUNITY proliferation infiltration immunosuppressive cells remodeling immune microenvironment immunosuppressive microenvironment 
Accelerating C-C coupling in alkaline electrochemical CO_(2)reduction by optimized local water dissociation kinetics
《Chinese Journal of Catalysis》2025年第4期128-137,共10页Qingfeng Hua Hao Mei Guang Feng Lina Su Yanan Yang Qichang Li Shaobo Li Xiaoxia Chang Zhiqi Huang 
国家自然科学基金(22208019,22278002).
Electrochemical carbon dioxide reduction reaction(CO_(2)RR)produces valuable chemicals by consuming gaseous CO_(2)as well as protons from the electrolyte.Protons,produced by water dissociation in alkaline electrolyte,...
关键词：CO_(2)reduction PROTON MICROENVIRONMENT Optimized local water dissociation kinetics CO_(2)activation Asymmetric coupling 
The important role and core marker gene of tumor-infiltrating plasma cells in the microenvironment of lung adenocarcinoma
《Genes & Diseases》2025年第2期11-14,共4页Jianhong Zhang Chengyang Song Xiuqin Feng QianYu Xueying Yang 
supported by the support for High-quality Development of Scientific Research Funding Project of China Medical University (No.2023JH2/20200137).
Lung adenocarcinoma(LUAD)is the primary subtype of lung cancer,but its prognosis remains challenging.The tumor microenvironment plays a central role in the initiation and development of tumors,particularly regarding t...
关键词：ADENOCARCINOMA LUNG PROGNOSIS 
Microenvironment engineering of nitrogen-doped hollow carbon spheres encapsulated with Pd catalysts for highly selective hydrodeoxygenation of biomass-derived vanillin in water
《Chinese Journal of Catalysis》2025年第4期267-284,共18页Jun Wu Liqian Liu Xinyue Yan Gang Pan Jiahao Bai Chengbing Wang Fuwei Li Yong Li 
国家自然科学基金(21902094,22472177);陕西省自然科学基金(2023-JC-QN-0103);中国博士后面上基金(2020M683405);陕西省教育厅科研计划项目(23JK0344).
Development of efficient and stable metal catalysts for the selective aqueous phase hydrodeoxygenation(HDO)of biomass-derived oxygenates to value-added biofuels is highly desired.An innovative surface microenvironment...
关键词：Microenvironment modulation Nitrogen-doped hollow carbon sphere Pd-based catalyst Electronic metal-support interaction HYDRODEOXYGENATION VANILLIN 
Tissue Engineering and Spinal Cord Injury Repair
《Engineering》2025年第3期60-72,共13页Lai Xu Songlin Zhou Xiu Dai Xiaosong Gu Zhaolian Ouyang 
supported by grants from the National Natural Science Foundation of China(92368207);the Chinese Academy of Engineering(2023-SBZD-11);the Natural Science Foundation of Jiangsu Province(BK20232023).
Tissue engineering and regenerative medicine is a new interdisciplinary subject integrating life science,material science,engineering technology,and clinical medicine.Over the last ten years,significant advancements h...
关键词：Tissue engineering Spinal cord injury Regenerative microenvironment 
Dual functional nanoplatforms potentiate osteosarcoma immunotherapy via microenvironment modulation
《National Science Review》2025年第3期363-378,共16页Shunyi Lu Yuqi Yang Zhuorun Song Jie Cao Zhihui Han Linfu Chen Yunfei He Jiayi Wang Yun Teng Zengli Zhang Jun Zou Jun Ge Huilin Yang Liang Cheng 
suppor ted by the National Key Re-search and Development Program of China(2022YFB3804600);the National Natural Science Foundation of China(52472288,82172506 and 82030068);the Collaborative Innovation Center of Suzhou Nano Science and Technology,the Suzhou Key Laboratory of Nanotechnology and Biomedicine,the Science and Technology Development Fund,the Macao SAR(0118/2023/RIA2,0064/2024/AMJ and 0016/2024/RIA1);the Jiangsu Natural Science Fund for Distinguished Young Scholars(BK20211544);the Overseas Expertise Introduction Project for Discipline Innovation(111 Project);the Joint International Research Laboratory of Carbon-Based Functional Materials and Devices,the Jiangsu Funding Program for Excellent Postdoctoral Talent(2024ZB491);the China Postdoctoral Science Foundation(2024M752333);the Natural Science Foundation BoXi Cultivation Program Project of the First Affiliated Hospital of Soochow University(BXQN2023013).
Osteosarcoma(OS),a highly aggressive bone tumor,presents significant challenges in terms of effective treatment.We identified that cellular autophagy was impaired within OS by comparing clinical OS samples through bio...
关键词：OSTEOSARCOMA metal nanoplatform MnSx H2 S gas therapy AUTOPHAGY IMMUNOTHERAPY 
Harnessing multi-omics approaches to elucidate the role of Chinese herbal compounds in chemotherapy-induced gastrointestinal damage
《World Journal of Gastrointestinal Oncology》2025年第2期35-40,共6页Chang Qiao Hao-Xiang Zhang Xiao-Tong Tian Yan-Jing Zhang De-Hui Li 
Supported by 2023 Government-funded Project of the Outstanding Talents Training Program in Clinical Medicine,No.ZF2023165;Key Research and Development Projects of Hebei Province,No.18277731D;Natural Science Foundation of Hebei Province,No.H202423105.
In this editorial,we discuss the findings reported by Wang et al in the latest issue of the World Journal of Gastrointestinal Oncology.Various research methodologies,including microbiome analysis,assert that the Tzu-C...
关键词：Chinese herbal compounds Gastrointestinal microenvironment CHEMOTHERAPY Multi-omics Intestinal microecology 
In situ formed fluorescent gold nanoclusters inhibit hair follicle regeneration in oxidative stress microenvironment via suppressing NFκB signal pathway
《Chinese Chemical Letters》2025年第2期256-260,共5页Xiangdong Lai Tengfei Liu Zengchao Guo Yihan Wang Jiang Xiao Qingxiu Xia Xiaohui Liu Hui Jiang Xuemei Wang 
supported by the National Natural Science Foundation of China(Nos.82061148012,82027806,82372220,21974019);the National Key Research and Development Program of China(No.2017YFA0205300);the Primary Research&Development Plan of Jiangsu Province(No.BE2019716)。
Skins expose to kinds of risk factors for damage,such as the hormone drugs,skin care products and ultraviolet radiation,which is accompanied by the production of excessive reactive oxygen species(ROS)and eventually le...
关键词：Fluorescent gold nanoclusters Skin injury Reactive oxygen species Hair follicle regeneration Oxidative stress microenvironment 
Highly portable electrochemical oxygen removal device for microenvironmental low-oxygen control
《Nano Research》2025年第2期263-272,共10页Xin Wang Xingen Lin Wanyu Shen Yimin Li Yi Tan Zihan Wang Peng Jiang Song Gong Kong Chen Yu Zhang Yuen Wu 
This work was supported by China Ministry of Science and Technology(No.2021YFA1600800);the National Natural Science Foundation of China(Nos.92261105,22221003,and 22401194);the Joint Funds of the National Natural Science Foundation of China(No.U23A2081);China Postdoctoral Science Foundation funded project(No.2022M712178);the Anhui Provincial Natural Science Foundation(Nos.2108085UD06 and 2208085UD04);the Anhui Provincial Key Research and Development Project(Nos.2023z04020010 and 2022a05020053);the Fundamental Research Funds for the Centre Universities(No.WK9990000155);the Joint Funds from Hefei National Synchrotron Radiation Laboratory(Nos.KY2060000180 and KY2060000195);the USTC Research Funds of the Double First-Class Initiative(No.YD2060006005).
Low-oxygen(O_(2))environments are essential in various research and application fields,yet traditional methods like nitrogen flushing or chemical O_(2) absorbers face challenges in high equipment cost and low controll...
关键词：low-oxygen condition oxygen reduction reaction(ORR) oxygen level control for microenvironment electrochemical oxygen removal 
Maternal stress and the early embryonic microenvironment:investigating long‑term cortisol effects on bovine oviductal epithelial cells using air–liquid interface culture
《Journal of Animal Science and Biotechnology》2025年第1期153-166,共14页Fiona Wahl Jianchao Huo Shuaizhi Du Jennifer Schoen Shuai Chen 
German research Foundation(DFG,grant numbers:CH2321/1–1 and SCHO1231/7–1);JH has received a scholarship from the Chinese Scholarship Council(CSC No.:201908350115).
The oviduct epithelium is the initial maternal contact site for embryos after fertilization,offering the microenviron-ment before implantation.This early gestation period is particularly sensitive to stress,which can ...
关键词：Air–liquid interface BOVINE CORTISOL Early embryonic microenvironment Epithelial cells Maternal stress OVIDUCT 
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