POTENTIAL

作品数:3519被引量:6314H指数:27
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相关领域:医药卫生更多>>
相关作者:韦峥姚泽恩王超牛彦徐萍更多>>
相关机构:北京大学复旦大学中国科学院上海交通大学更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划中国博士后科学基金国家教育部博士点基金更多>>
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P2X7 receptors and multiple sclerosis: A potential biomarker and therapeutic target?
《Neural Regeneration Research》2026年第1期318-319,共2页Cristina Agliardi Franca Rosa Guerini Mario Clerici 
supported by Italian Ministry of Health Ricerca Corrente [RC 2023] and RF-2016-02361294;supported by#NEXTGENERATIONEU (NGEU);funded by the Ministry of University and Research (MUR);National Recovery and Resilience Plan (NRRP);project MNESYS (PE0000006)–A Multiscale integrated approach to the study of the nervous system in health and disease (DN. 1553 11.10.2022)(to FRG);partially supported by a grant from Fondazione Romeo ed Enrica Invernizzi (to FRG)。
Multiple sclerosis(MS) is a chronic, autoimmune and neuroinflammatory disease of the central nervous system(CNS) with a neurodegenerative component, characterized by demyelination and degeneration of nerve fibers. It ...
关键词:SCLEROSIS DEGENERATION THERAPEUTIC 
Potential treatment of Alzheimer's disease astrocyte pathology based on nuclear lipid regulation
《Neural Regeneration Research》2026年第1期322-323,共2页Masato Komai Nobumasa Takasugi 
supported by a grant from the Japan Foundation for applied enzymology (to NT);the Grant-in-Aid for Scientific Research (C) from the Japan Society for the Promotion of Science (26430059, 17K08272, and 20K07014 to NT);the establishment of university fellowships toward the creation of science technology innovation (JPMJFS2128);a Grant-in-Aid for JSPS Fellows (23KJ1603)(to MK)。
The purpose of this perspective is to discuss the future development of a potential treatment of glial pathology in Alzheimer's disease(AD) and a new regulatory mechanism, nuclear lipids, which may be involved in the ...
关键词:PATHOLOGY ALZHEIMER 
Syndecans in Alzheimer's disease:pathogenetic mechanisms and potential therapeutic targets
《Neural Regeneration Research》2025年第9期2594-2595,共2页Carmela Rita Balistreri Roberto Monastero 
supported by grants from the Next Generation EU-MUR D.M.737/2021-Project PSEBPEHRD-CUP B79J21038330001(to CRB)。
With increasing age,humans become more susceptible to the onset of neurodegenerative diseases(NDs),and among these,Alzheimer's disease(AD)is the most frequent(Nicoletti et al.,2023).NDs are primarily characterized by ...
关键词:ALZHEIMER CARDIOVASCULAR 
Protein arginine methyltransferase-6 regulates heterogeneous nuclear ribonucleoprotein-F expression and is a potential target for the treatment of neuropathic pain
《Neural Regeneration Research》2025年第9期2682-2696,共15页Xiaoyu Zhang Yuqi Liu Fangxia Xu Chengcheng Zhou Kaimei Lu Bin Fang Lijuan Wang Lina Huang Zifeng Xu 
supported by the National Natural Science Foundation of China,Nos.82001178(to LW),81901129(to LH),82001175(to FX);Shanghai Sailing Program,No.20YF1439200(to LW);the Natural Science Foundation of Shanghai,China,No.23ZR1450800(to LH);and the Fundamental Research Funds for the Central Universities,No.YG2023LC15(to ZX)。
Protein arginine methyltransferase-6 participates in a range of biological functions,particularly RNA processing,transcription,chromatin remodeling,and endosomal trafficking.However,it remains unclear whether protein ...
关键词:dorsal root ganglion heterogeneous nuclear ribonucleoprotein F neuropathic pain protein arginine methyltransferase-6 sensory neurons 
Many faces of neuronal activity manipulation in Drosophila
《Neural Regeneration Research》2025年第9期2574-2576,共3页Amber Krebs Steffen Kautzmann Christian Klämbt 
Animals exhibit complex responses to external and internal stimuli.The information is computed by interconnected neurons that express numerous ion channels,which modulate the neuronal membrane potential.How can neuron...
关键词:MANIPULATION potential. NEURONAL 
The role of lncRNAs in AKI and CKD:Molecular mechanisms,biomarkers,and potential therapeutic targets
《Genes & Diseases》2025年第3期278-296,共19页Minhui Zheng Zixuan Yang Lei Shi Liyuan Zhao Kelan Liu Naping Tang 
Exosomes, a type of extracellular vesicle, are commonly found in different bodyfluids and are rich in nucleic acids (circRNA, lncRNAs, miRNAs, mRNAs, tRNAs, etc.), proteins,and lipids. They are involved in intercellul...
关键词:Acute kidney injury BIOMARKER Chronic kidney disease EXOSOME lncRNA Renal fibrosis 
Civil aviation emissions in China in 2019:Characteristics and abatement potential
《Journal of Environmental Sciences》2025年第5期225-237,共13页Haowen An Yu Wang Yaxin Wang Jun Liu Xiaolong Tang Honghong Yi 
supported by the National Natural Science Foundation of China(Nos.42375171 and 42105157);the Interdisciplinary Research Project for Young Teachers of USTB(No.06600083);Energy Foundation(Nos.G-2109-33379 and G-2306-34754);the Fundamental Research Funds for the Central Universities(No.06500166).
Civil aviation is one of the industries facing the greatest challenge in reaching carbon neutrality by the middle of this century,and this sector also contributes to adverse impacts on the regional air quality and hum...
关键词:Emission inventory Fuel flow method Cruise emission Age structure Reduction measures 
Investigation of oxidative potential of fresh and O_(3)-aging PM_(2.5)from various emission sources across urban and rural regions
《Journal of Environmental Sciences》2025年第5期608-615,共8页Shuaishuai Ma Dongsheng Cheng Yingying Tang Younuo Fan Qiong Li Chengxiang He Zhiqing Zhao Tianyou Xu 
supported by the National Natural Science Foundation of China(No.42305109);Quzhou Municipal Science and Technology Bureau(No.2023K222).
Inhalation of atmospheric PM_(2.5)can induce the generation of excessive reactive oxygen species(ROS)in human alveoli,triggering local and systemic inflammation,which can directly or indirectly result in respiratory a...
关键词:Atmospheric PM_(2.5) Oxidative potential Emission sources DTT assay O_(3)aging 
Numerical simulation of size contraction of Typhoon Cempaka(2021)
《Atmospheric and Oceanic Science Letters》2025年第2期29-35,共7页Lingfeng Sun Qingqing Li 
jointly supported by the National Natural Science Foundation of China[grant numbers U2342202 and 42175005];the Qing Lan Project[grant number R2023Q06]。
In 2021,Cempaka,a tiny tropical cyclone,made landfall in China.As the TC intensified prior to landfall,the tropical cyclone size measured with precipitation decreased significantly.A numerical simulation was conducted...
关键词:Typhoon cempaka Vortex size contraction Potential vorticity budget Asymmetric structure Outer rainband 
Application of Deep-Learning Potential in Simulating the Structural and Physical Characteristics of Platinum
《Computers, Materials & Continua》2025年第4期685-700,共16页Keyuan Chen Xingkao Zhang Li Ma Jueyi Ye Qi Qiu Haoxiang Zhang Ju Rong Yudong Sui Xiaohua Yu Jing Feng 
supported by the Kunming University of Science and Technology“Double First-Class”Joint Special Project(Grant No.202101BE070001-011);Yunnan Fundamental Research Projects(202201BE070001-008,202201AT070192);National Natural Science Foundation of China(52402077);Shaanxi Province Key R&D Program(2021ZDLGY11-08);Open Project of Shaanxi Laboratory(2021SXsyS01-05);Open Project of Yunnan Precious Metals Laboratory(YPML-2023050240);National Natural Science Foundation of China(Grant No.52462009);Yunnan Fundamental Research Projects(Grant Nos.202201AT070192,202101BE070001-011).
The deep potential(DP)is an innovative approach based on deep learning that uses ab initio calculation data derived from density functional theory(DFT),to create high-accuracy potential functions for various materials...
关键词:Deep learning ab initio calculations phase transitions molecular dynamics simulations 
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