NEURONAL

作品数:483被引量:973H指数:14
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相关领域:医药卫生生物学更多>>
相关作者:高昌俊孙绪德陶蕾刘磊徐如祥更多>>
相关机构:中国科学院华中科技大学复旦大学中国科学院遗传与发育生物学研究所更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划广东省自然科学基金中国博士后科学基金更多>>
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Sesquiterpene lactones as potential drugs treating nerve injury
《Neural Regeneration Research》2026年第2期671-672,共2页Philipp Gobrecht Marco Leibinger Dietmar Fischer 
supported by The German Research Foundation.
Traumatic axonal lesions of peripheral nerves disrupt neuronal connections with their targets,resulting in the loss of motor and sensory functions.Despite the peripheral nervous system’s capacity for axonal regrowth,...
关键词:traumatic axonal lesions peripheral nervous system s axonal regrowththis permanent impairements nerve injury peripheral nerves disrupt neuronal connections sesquiterpene lactones 
Neuronal autosis:the self-destructive side of autophagy involved in hypoxic-ischemic neuronal death
《Neural Regeneration Research》2025年第12期3517-3518,共2页Vanessa Ginet Pauline Depierre Julien Puyal 
supported by grants from the Swiss National Science Foundation(310030-182332 and 310030L-208141)(to JP)。
The challenge of protecting the brain resides in the unique characteristics of neurons,as they are postmitotic,long-lived,excitable,and polarized cells with long and fragile axons and dendrites.The complexity of the m...
关键词:DEATH HYPOXIC polarized 
Disruption of neuronal actin barrier promotes the entry of disease-implicated proteins to exacerbate amyotrophic lateral sclerosis pathology
《Neural Regeneration Research》2025年第9期2589-2590,共2页Mikio Shimizu Tatsusada Okuno 
supported in port by the JSPS KAKENHI(grant number 22K07539 to MS);funded by Mitsubishi Tanabe Pharma Corporation。
Amyotrophic lateral sclerosis(ALS)is a devastating neurological disease characterized by the accumulation of aberrant proteins in motor neurons of the brain and spinal cord.Patients with ALS develop skeletal muscle we...
关键词:PARALYSIS SCLEROSIS 
Many faces of neuronal activity manipulation in Drosophila
《Neural Regeneration Research》2025年第9期2574-2576,共3页Amber Krebs Steffen Kautzmann Christian Klämbt 
Animals exhibit complex responses to external and internal stimuli.The information is computed by interconnected neurons that express numerous ion channels,which modulate the neuronal membrane potential.How can neuron...
关键词:MANIPULATION potential. NEURONAL 
Apolipoprotein E elicits targetdirected miRNA degradation to maintain neuronal integrity
《Neural Regeneration Research》2025年第9期2577-2578,共2页Jiazi Tan Chin-Tong Ong 
supported by core funding provided by Temasek Life Sciences Laboratory(to CTO)。
Apolipoprotein E has diverse functions in neurons:Apolipoprotein E(ApoE)is a glycoprotein that primarily regulates lipid metabolism and transport in the central nervous system.There are three predominant human ApoE pr...
关键词:METABOLISM GLYCOPROTEIN MAINTAIN 
In vivo direct neuronal conversion as a therapeutic strategy for ischemic stroke被引量:1
《Neural Regeneration Research》2025年第8期2309-2310,共2页Takashi Irie Taito Matsuda 
supported by JSPS KAKENHI Grant Number JP24K18622(to TI);JSPS KAKENHI Grant Number JP23K18451(to TM)。
Stroke causes neuronal loss,which ultimately results in persistent neurological dysfunction.Globally,stroke was the third-leading cause of death and disability combined in all ages in 2019,after neonatal disorders and...
关键词:NEONATAL DEATH THERAPEUTIC 
Neuronal regulated cell death in aging-related neurodegenerative diseases:key pathways and therapeutic potentials
《Neural Regeneration Research》2025年第8期2245-2263,共19页Run Song Shiyi Yin Jiannan Wu Junqiang Yan 
supported by the Key Projects of Medical Science and Technology of Henan Province,No.SBGJ202002099(to JY)。
Regulated cell death(such as apoptosis,necroptosis,pyroptosis,autophagy,cuproptosis,ferroptosis,disulfidptosis)involves complex signaling pathways and molecular effectors,and has been proven to be an important regulat...
关键词:apoptosis autophagy cuproptosis disulfidptosis ferroptosis NECROPTOSIS neurodegenerative disease neurological aging diseases PANoptosis PYROPTOSIS 
Glycolytic dysregulation in Alzheimer's disease:unveiling new avenues for understanding pathogenesis and improving therapy
《Neural Regeneration Research》2025年第8期2264-2278,共15页You Wu Lijie Yang Wanrong Jiang Xinyuan Zhang Zhaohui Yao 
supported by the National Natural Science Foundation of China,No.82271214(to ZY);the Natural Science Foundation of Hubei Province of China,No.2022CFB109(to ZY)。
Alzheimer's disease poses a significant global health challenge owing to the progressive cognitive decline of patients and absence of curative treatments.The current therapeutic strategies,primarily based on cholinest...
关键词:Alzheimer’s disease glial cells GLYCOLYSIS neuronal metabolism PATHOGENESIS therapeutic targets 
NOX4 exacerbates Parkinson's disease pathology by promoting neuronal ferroptosis and neuroinflammation
《Neural Regeneration Research》2025年第7期2038-2052,共15页Zhihao Lin Changzhou Ying Xiaoli Si Naijia Xue Yi Liu Ran Zheng Ying Chen Jiali Pu Baorong Zhang 
supported by the National Natural Science Foundation of China,Nos.82271444(to JP),82271268(to BZ),and 82001346(to YL);the National Key Research and Development Program of China,No.2022YFE0210100(to BZ)。
Parkinson's disease is primarily caused by the loss of dopaminergic neurons in the substantia nigra compacta.Ferroptosis,a novel form of regulated cell death characterized by iron accumulation and lipid peroxidation,p...
关键词:dopaminergic neuron ferroptosis NADPH oxidase 4(NOX4) NEUROINFLAMMATION Parkinson's disease 
Neurogenesis dynamics in the olfactory bulb:deciphering circuitry organization, function, and adaptive plasticity
《Neural Regeneration Research》2025年第6期1565-1581,共17页Moawiah M.Naffaa 
Adult neurogenesis persists after birth in the subventricular zone, with new neurons migrating to the granule cell layer and glomerular layers of the olfactory bulb, where they integrate into existing circuitry as inh...
关键词:network adaptability NEUROGENESIS neuronal communication olfactory bulb olfactory learning olfactory memory synaptic plasticity 
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