HYPOXIC

作品数：309被引量：946H指数：15
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相关领域：医药卫生更多>>
相关作者：谭双香戴爱国胡瑞成丁艳洁蒋犁更多>>
相关机构：南华大学首都医科大学北京大学第一医院中国医科大学更多>>
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相关基金：国家自然科学基金国家重点基础研究发展计划中国博士后科学基金北京市自然科学基金更多>>
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Neuronal autosis:the self-destructive side of autophagy involved in hypoxic-ischemic neuronal death
《Neural Regeneration Research》2025年第12期3517-3518,共2页Vanessa Ginet Pauline Depierre Julien Puyal 
supported by grants from the Swiss National Science Foundation(310030-182332 and 310030L-208141)(to JP)。
The challenge of protecting the brain resides in the unique characteristics of neurons,as they are postmitotic,long-lived,excitable,and polarized cells with long and fragile axons and dendrites.The complexity of the m...
关键词：DEATH HYPOXIC polarized 
Brain scarring in infants:immunological insights from a neonatal hypoxic-ischemic encephalopathy model
《Neural Regeneration Research》2025年第10期2909-2910,共2页Pedro Moreno Pimentel-Coelho 
supported by Fundação de AmparoàPesquisa do Estado do Rio de Janeiro(FAPERJ,E-26/010.002160/2019,E-26/203.227/2017,E-260003/001177/2020,and E-26/201.279/2021);Conselho Nacional de Desenvolvimento Científico e Tecnológico(CNPq,313757/2020-8,311188/2023-0)(to PMPC).
Neonatal hypoxic-ischemic encephalopathy(HIE)is a significant cause of disability in children.Improving brain function and accelerating neurological recovery may require a combination of neuroprotective and pro-regene...
关键词：NEONATAL protective HYPOXIC 
Stem cell therapy for intervertebral disc degeneration:Clinical progress with exosomes and gene vectors
《World Journal of Stem Cells》2025年第4期20-35,共16页Zhi-Peng Li Han Li Yu-Hua Ruan Peng Wang Meng-Ting Zhu Wei-Ping Fu Rui-Bo Wang Xiao-Dong Tang Qi Zhang Sen-Li Li He Yin Cheng-Jin Li Yi-Gong Tian Rui-Ning Han Yao-Bin Wang Chang-Jiang Zhang 
Supported by Henan Province Key Research and Development Program,No.231111311000;Henan Provincial Science and Technology Research Project,No.232102310411;Henan Province Medical Science and Technology Key Project,No.LHGJ20220566 and No.LHGJ20240365;Henan Province Medical Education Research Project,No.WJLX2023079;and Zhengzhou Medical and Health Technology Innovation Guidance Program,No.2024YLZDJH022.
Intervertebral disc degeneration is a leading cause of lower back pain and is characterized by pathological processes such as nucleus pulposus cell apoptosis,extracellular matrix imbalance,and annulus fibrosus rupture...
关键词：EXOSOMES Extracellular matrix repair Gene vector system Hypoxic environment Intervertebral disc degeneration Mesenchymal stem cells Regenerative medicine Stem cell therapy 
Hypoxic endometrial epithelial cell-derived microRNAs effectively regulate the regenerative properties of mesenchymal stromal cells
《World Journal of Stem Cells》2025年第4期150-154,共5页Panagiotis Mallis 
Endometrial thickness plays an important role in successful embryo implantation and normal pregnancy achievement.However,a thin endometrial layer(≤7 mm)may have a significant effect on microenvironment tolerance,whic...
关键词：MICRORNAS Mesenchymal stromal cells Endometrial tissue Wound healing Tissue regeneration MiR-214-5p MiR-21-5p 
Impact of miR-214-5p and miR-21-5p from hypoxic endometrial exosomes on human umbilical cord mesen-chymal stem cell function
《World Journal of Stem Cells》2025年第2期137-140,共4页Jin-Wei Zhang 
the National Natural Science Foundation of China,No.82170406 and No.81970238;the Royal Society United Kingdom,No.IEC\NSFC\201094.
Exosomes derived from hypoxic endometrial epithelial cells are pivotal in cellular communication and tissue repair,offering new perspectives on reproductive health.This manuscript highlights the study by Zhang et al,w...
关键词：MiR-214-5p MiR-21-5p Hypoxic endometrial epithelial cells EXOSOMES Human umbilical cord mesenchymal stem cells Signal transducer and activator of transcription 3 signaling Thin endometrium INFERTILITY 
Nicotinamide adenine dinucleotide treatment confers resistance to neonatal ischemia and hypoxia:effects on neurobehavioral phenotypes
《Neural Regeneration Research》2024年第12期2760-2772,共13页Xiaowen Xu Xinxin Wang Li Zhang Yiming Jin Lili Li Meifang Jin Lianyong Li Hong Ni 
supported by the National Natural Science Foundation of China,Nos.81871024 (to HN),82301957 (to XW),82001382 (to LL),62127810 (to HN);the Natural Science Foundation of Jiangsu Province of China,No.SBK2020040785 (to LL)。
Neonatal hypoxic-ischemic brain injury is the main cause of hypoxic-ischemic encephalopathy and cerebral palsy.Currently,there are few effective clinical treatments for neonatal hypoxic-ischemic brain injury.Here,we i...
关键词：brain injury cerebral palsy HYPOXIA hypoxic-ischemic brain injury inflammation NEUROPROTECTION nicotinamide adenine dinucleotide NEONATE nicotinamide adenine dinucleotide PROTEOMICS 
Delayed post-hypoxic leukoencephalopathy (DPHL) after smoke inhalation from dry burning carbonization poisoning: a case report
《Journal of Translational Neuroscience》2024年第4期52-56,共5页Yuejiao Fu 
Objective:To describe the clinical fea-tures of delayed post-hypoxic leukoencephalopathy after smoke inhalation from dry burning.Methods:We col-lected the clinical history and examination data of a pa-tient who presen...
关键词：delayed post-hypoxic leukoencepha-lopathy dry burning CARBONIZATION 
A novel perspective in stroke neuroprotection:Leveraging hypoxic pocket insights for studying preconditioning and postconditioning
《Neuroprotection》2024年第4期288-295,共8页Heng Zhao Yan Meng Sijie Li Guiyou Liu Xunming Ji 
This perspective article delineates the significant role of hypoxic pockets—localized,transient reductions in cerebral oxygenation—and their implications for stroke neuroprotection strategies.It posits that precondi...
关键词：hypoxic pocket NEUROPROTECTION POSTCONDITIONING PRECONDITIONING STROKE 
Effects of miR-214-5p and miR-21-5p in hypoxic endometrial epithelial-cell-derived exosomes on human umbilical cord mesenchymal stem cells
《World Journal of Stem Cells》2024年第11期906-925,共20页Wan-Yu Zhang Han-Bi Wang Cheng-Yan Deng 
Supported by the National High Level Hospital Clinical Research Funding,No.2022-PUMCH-B-080 and No.2022-PUMCH-C-064.
BACKGROUND Thin endometrium seriously affects endometrial receptivity,resulting in a significant reduction in embryo implantation,and clinical pregnancy and live birth rates,and there is no gold standard for treatment...
关键词：Endometrial epithelial cells EXOSOMES Human umbilical cord mesenchymal stem cells MiR-214-5p/miR-21-5p Signal transducer and activator of transcription 3 
Spectrum of delayed post-hypoxic leukoencephalopathy syndrome:A systematic review
《World Journal of Clinical Cases》2024年第29期6285-6301,共17页Bahadar S Srichawla Maria A Garcia-Dominguez 
BACKGROUND Delayed post hypoxic leukoencephalopathy syndrome(DPHLS),also known as Grinker’s myelinopathy,is a rare but significant neurological condition that manifests days to weeks after a hypoxic event.Characteriz...
关键词：Delayed post hypoxic leukoencephalopathy syndrome Anoxic encephalopathy Delayed post hypoxic leukoencephalopathy Hypoxic-ischemic brain injury Grinker's myelinopathy Toxic leukoencephalopathy Toxic leukoencephalopathy Delayed postanoxic encephalopathy Carbon monoxide poisoning 
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